Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shiting Gu"'
Publikováno v:
Analytical Chemistry. 93:2706-2712
Accurate and sensitive detection of targets in practical biological matrixes such as blood, plasma, serum, or tissue fluid is a frontier issue for most biosensors since the coexistence of both potential reducing agents and protein molecules has the p
Publikováno v:
Electrochimica Acta. 318:100-107
A promising electrode with three-dimensional (3D) AuNPs/ZnO/Cu2O heterojunction nanowires (NWs) was developed and applied as photocathode for sensitive photoelectrochemical (PEC) immunoassay toward carcinoembryonic antigen (CEA, Ag). Firstly, Cu2O NW
Publikováno v:
Biosensorsbioelectronics. 168
Photocathodic bioassays have shown great potential to apply in real bio-sample detection owning to their intrinsic abilities against interference from reductive species. However, the pursuit of photocathodic bioassays with excellent detection perform
Publikováno v:
Sensors and Actuators B: Chemical. 343:130060
Herein, a novel and robust two-electrode photoelectrochemical (PEC) biosensing platform amplified by bilirubin oxidase (BOD) labelling was reported. This two-electrode operating system was composed of photoanode and sensing biocathode. Carcinoembryon
Publikováno v:
Sensors and Actuators B: Chemical. 330:129331
Photocathodic immunoassays show brilliant prospect for practical detection in biological matrix owning to the inherent strength against signal interference from potential reductive molecules. However, their exploration with advanced and efficient sig
Autor:
Dan Xiao, Wen Zhang, Xiaoting Guo, Yidong Liu, Chunxia Hu, Shiting Guo, Zhaoqi Kang, Xianzhi Xu, Cuiqing Ma, Chao Gao, Ping Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
d-2-hydroxyglutarate (d-2-HG) is a metabolite that can be aberrantly accumulated and acts as a biomarker in many cancers. Here the authors report a d-2-HG biosensor based on the allosteric transcription factor DhdR which they use for detection in ser
Externí odkaz:
https://doaj.org/article/1248620f2af4490098671ea1ea56cc9b
Autor:
Wensi Meng, Lijie Zhang, Menghao Cao, Yongjia Zhang, Yipeng Zhang, Ping Li, Zhaoqi Kang, Shiting Guo, Ping Xu, Cuiqing Ma, Chao Gao
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-12 (2021)
Abstract Overflow metabolism-caused acetate accumulation is a major problem that restricts industrial applications of various bacteria. 2,3-Butanediol (2,3-BD) synthesis in microorganisms is an ancient metabolic process with unidentified functions. W
Externí odkaz:
https://doaj.org/article/d9d18904b4ea49aab08d5971979dbd20
Autor:
Zhaoqi Kang, Manman Zhang, Kaiyu Gao, Wen Zhang, Wensi Meng, Yidong Liu, Dan Xiao, Shiting Guo, Cuiqing Ma, Chao Gao, Ping Xu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
L-2-hydroxyglutarate (L-2-HG) is an important metabolite but its regulation is poorly understood. Here the authors report an L-2-HG FRET biosensor based on the allosteric transcription factor, LhgR, to monitor L-2-HG in cells and biological samples.
Externí odkaz:
https://doaj.org/article/f6f1f3484bad43509543b1abe04c2573
Autor:
Manman Zhang, Chao Gao, Xiaoting Guo, Shiting Guo, Zhaoqi Kang, Dan Xiao, Jinxin Yan, Fei Tao, Wen Zhang, Wenyue Dong, Pan Liu, Chen Yang, Cuiqing Ma, Ping Xu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
It is known that the five carbon platform chemical glutarate can be catabolized by the glutaryl-CoA dehydrogenation pathway. Here, the authors discover an additional glutarate catabolic pathway involving l-2-hydroxyglutarate and show increased glutar
Externí odkaz:
https://doaj.org/article/410d386a718d45bba309100ab02c7216
Autor:
Manman Zhang, Zhaoqi Kang, Xiaoting Guo, Shiting Guo, Dan Xiao, Yidong Liu, Cuiqing Ma, Ping Xu, Chao Gao
Publikováno v:
mBio, Vol 10, Iss 4 (2019)
ABSTRACT Glutarate, a metabolic intermediate in the catabolism of several amino acids and aromatic compounds, can be catabolized through both the glutarate hydroxylation pathway and the glutaryl-coenzyme A (glutaryl-CoA) dehydrogenation pathway in Ps
Externí odkaz:
https://doaj.org/article/859c880cd71348b2b576a7b894a35865