Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shishang Qin"'
Autor:
Boxi Kang, Jordi Camps, Biao Fan, Hongpeng Jiang, Mahmoud M. Ibrahim, Xueda Hu, Shishang Qin, Dennis Kirchhoff, Derek Y. Chiang, Shan Wang, Yingjiang Ye, Zhanlong Shen, Zhaode Bu, Zemin Zhang, Helge G. Roider
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-25 (2022)
Abstract Background The tumor microenvironment (TME) has been shown to strongly influence treatment outcome for cancer patients in various indications and to influence the overall survival. However, the cells forming the TME in gastric cancer have no
Externí odkaz:
https://doaj.org/article/f607a81be80f4944938163ec4f1a798d
Autor:
Liqin Xu, Yuxiang Ma, Chao Fang, Zhuobing Peng, Fangfang Gao, Janne Marie Moll, Shishang Qin, Qichao Yu, Yong Hou, Karsten Kristiansen, Wenfeng Fang, Susanne Brix, Li Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Antibodies targeting the programmed cell death protein-1 (PD-1) molecule have been reported to hold promising antitumor activities in patients with nasopharyngeal carcinoma (NPC). However, only a small subset of NPC patients benefits from the anti-PD
Externí odkaz:
https://doaj.org/article/9c735f4571e9471cb0345bbecb45a53d
Autor:
Rui Yang, Amanda S. Meyer, Ilia A. Droujinine, Namrata D. Udeshi, Yanhui Hu, Jinjin Guo, Jill A. McMahon, Dominique K. Carey, Charles Xu, Qiao Fang, Jihui Sha, Shishang Qin, David Rocco, James Wohlschlegel, Alice Y. Ting, Steven A. Carr, Norbert Perrimon, Andrew P. McMahon
Publikováno v:
Open Biology, Vol 12, Iss 8 (2022)
Organ functions are highly specialized and interdependent. Secreted factors regulate organ development and mediate homeostasis through serum trafficking and inter-organ communication. Enzyme-catalysed proximity labelling enables the identification of
Externí odkaz:
https://doaj.org/article/781665c34c2f419d899d2789c6add7ce
Autor:
Chao Fang, Wenfeng Fang, Liqin Xu, Fangfang Gao, Yong Hou, Hua Zou, Yuxiang Ma, Janne Marie Moll, Yunpeng Yang, Dan Wang, Yan Huang, Huahui Ren, Hongyun Zhao, Shishang Qin, Huanzi Zhong, Junhua Li, Sheng Liu, Huanming Yang, Jian Wang, Susanne Brix, Karsten Kristiansen, Li Zhang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundProgrammed death 1 (PD-1) and the ligand of PD-1 (PD-L1) are central targets for immune-checkpoint therapy (ICT) blocking immune evasion-related pathways elicited by tumor cells. A number of PD-1 inhibitors have been developed, but the effi
Externí odkaz:
https://doaj.org/article/6816f9ad31964128974dbb2fef4abee4
Autor:
Bing Yang, Zhen Zhang, Xiangjun Chen, Xu-Yan Wang, Shishang Qin, Liaoqi Du, Changjiang Yang, Liyu Zhu, Wenbo Sun, Yongjie Zhu, Qinwen Zheng, Shidong Zhao, Quan Wang, Long Zhao, Yilin Lin, Jinghe Huang, Fan Wu, Lu Lu, Fei Wang, Wenjie Zheng, Xiao-Hua Zhou, Xiaozhen Zhao, Ziye Wang, Sun Xiao-Lin, Yingjiang Ye, Shan Wang, Zhanguo Li, Hai Qi, Zemin Zhang, Dong-Ming Kuang, Lei Zhang, Zhanlong Shen, Wanli Liu
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 6 (2022)
Emerging studies have focused on ways to treat cancers by modulating T cell activation. However, whether B cell receptor signaling in the tumor microenvironment (TME) can be harnessed for immunotherapy is unclear. Here, we report that an Asia-specifi
Externí odkaz:
https://doaj.org/article/d41a1a865d6e485499d5512428741ed4
Autor:
Jun Wang, Sarah Gaughan, James T. Lamer, Cao Deng, Wanting Hu, Michael Wachholtz, Shishang Qin, Hu Nie, Xiaolin Liao, Qufei Ling, Weitao Li, Lifeng Zhu, Louis Bernatchez, Chenghui Wang, Guoqing Lu
Publikováno v:
Evolutionary Applications, Vol 13, Iss 2, Pp 263-277 (2020)
Abstract The genetic paradox of biological invasions is complex and multifaceted. In particular, the relative role of disparate propagule sources and genetic adaptation through postintroduction hybridization has remained largely unexplored. To add re
Externí odkaz:
https://doaj.org/article/b9757d2f7dd04ad2ab6959026df237b8
Autor:
Kedar Nath Natarajan, Zhichao Miao, Miaomiao Jiang, Xiaoyun Huang, Hongpo Zhou, Jiarui Xie, Chunqing Wang, Shishang Qin, Zhikun Zhao, Liang Wu, Naibo Yang, Bo Li, Yong Hou, Shiping Liu, Sarah A. Teichmann
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-8 (2019)
Abstract Single-cell RNA-seq technologies require library preparation prior to sequencing. Here, we present the first report to compare the cheaper BGISEQ-500 platform to the Illumina HiSeq platform for scRNA-seq. We generate a resource of 468 single
Externí odkaz:
https://doaj.org/article/66b4691e7a7a49749d396ac0be8abd99
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The extensive environmental adaptability of the genus Paenibacillus is related to the enormous diversity of its gene repertoires. Paenibacillus sp. SSG-1 has previously been reported, and its agar-degradation trait has attracted our attentio
Externí odkaz:
https://doaj.org/article/eb66f21eec3d4582b2f61edcc8a081d4
Autor:
Liqin, Xu, Yuxiang, Ma, Chao, Fang, Zhuobing, Peng, Fangfang, Gao, Janne Marie, Moll, Shishang, Qin, Qichao, Yu, Yong, Hou, Karsten, Kristiansen, Wenfeng, Fang, Susanne, Brix, Li, Zhang
Publikováno v:
Xu, L, Ma, Y, Fang, C, Peng, Z, Gao, F, Moll, J M, Qin, S, Yu, Q, Hou, Y, Kristiansen, K, Fang, W, Brix, S & Zhang, L 2022, ' Genomic and microbial factors affect the prognosis of anti-pd-1 immunotherapy in nasopharyngeal carcinoma ', Frontiers in Oncology, vol. 12, 953884 . https://doi.org/10.3389/fonc.2022.953884
Antibodies targeting the programmed cell death protein-1 (PD-1) molecule have been reported to hold promising antitumor activities in patients with nasopharyngeal carcinoma (NPC). However, only a small subset of NPC patients benefits from the anti-PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da2604e20e28d71ade58b1e4ecb60f2a
https://curis.ku.dk/portal/da/publications/genomic-and-microbial-factors-affect-the-prognosis-of-antipd1-immunotherapy-in-nasopharyngeal-carcinoma(b35db124-f959-4452-a62d-0c449d3cf929).html
https://curis.ku.dk/portal/da/publications/genomic-and-microbial-factors-affect-the-prognosis-of-antipd1-immunotherapy-in-nasopharyngeal-carcinoma(b35db124-f959-4452-a62d-0c449d3cf929).html
Autor:
Liangtao Zheng, Shishang Qin, Wen Si, Anqiang Wang, Baocai Xing, Ranran Gao, Xianwen Ren, Li Wang, Xiaojiang Wu, Ji Zhang, Nan Wu, Ning Zhang, Hong Zheng, Hanqiang Ouyang, Keyuan Chen, Zhaode Bu, Xueda Hu, Jiafu Ji, Zemin Zhang
Publikováno v:
Science. 374
An atlas of cancer-associated T cells The tumor microenvironment contains many different kinds of immune cells, the composition, function, and roles of which are unclear. Using single-cell RNA sequencing of T cells in 21 cancer types from more than 3