Small molecules block the polymerization of Z alpha1-antitrypsin and increase the clearance of intracellular aggregates.

Autor: Mallya M; Department of Medicine, University of Cambridge, Cambridge Institute for Medical Research, Wellcome Trust/MRC building, Cambridge CB2 2XY, UK., Phillips RL, Saldanha SA, Gooptu B, Brown SC, Termine DJ, Shirvani AM, Wu Y, Sifers RN, Abagyan R, Lomas DA

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2007 Nov 01; Vol. 50 (22), pp. 5357-63. Date of Electronic Publication: 2007 Oct 05.