Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Shiro Shigeta"'
Publikováno v:
Biomedicine & Pharmacotherapy
The anti-RNA virus activity of polyoxometalates (POM) is reviewed, with a special emphasis on the anti-respiratory virus activities. There are many causative agents of acute viral respiratory infections; and it is rather difficult to identify the rel
Autor:
Shiro Shigeta, Toshihiro Yamase
Publikováno v:
Antiviral Chemistry and Chemotherapy. 16:23-31
Severe acute respiratory syndrome (SARS) is a disease that has newly emerged in the 21st century, and is both severe and highly contagious. SARS first surfaced in late 2002 and spread within a few months from its origin in Guandong province, China, t
Autor:
Shuichi Mori, Mitsuaki Hosoya, Hitoshi Suzuki, Kenji Mori, Hiroshi Kimura, Shiro Shigeta, Akemi Tomoda, Yukio Sawaishi
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:4631-4635
Ribavirin is a broad-spectrum antiviral drug with inhibitory activity against many RNA viruses, including measles virus. Five patients with subacute sclerosing panencephalitis (SSPE) were treated with ribavirin by intraventricular administration. Alt
Autor:
Tomohiro Iida, Tatsuo Suzutani, Hisatoshi Kaneko, Osamu Suzuki, Koki Aoki, Shigeaki Ohno, Shuichi Mori, Masafumi Abe, Shiro Shigeta
Publikováno v:
Antiviral Research. 61:63-66
To determine the antiviral effects of compounds against ocular adenovirus (AdV) infection, we established an animal model of AdV infection in cotton rat eyes. Cotton rat eyes were inoculated intrastromally and topically with four AdV serotypes 4, 5,
Publikováno v:
Antiviral Research. 52:281-288
NMSO3, a sulfated sialyl lipid, was evaluated for its efficacy against adenovirus (AdV) in vitro. The median effective concentration (50% effective concentration, EC(50)) of NMSO3 against replication of AdV type 2 (AdV2), type 4 (AdV4), type 8 (AdV8)
Autor:
Manabu Tamura, Kazuo Takahashi, Mitsuo Shichinohe, Koichi Yamanishi, Shiro Shigeta, Toshiya Aono, Yasuhide Iwata
Publikováno v:
Microbiology and Immunology. 45:635-638
Herpes simplex virus-1 (HSV) or varicella zoster virus (VZV) DNA was detected by nested polymerase chain reaction in peripheral blood mononuclear cells of patients with Meniere's disease (one of 28 patients for HSV-1, 2 of 28 patients for VZV) during
Autor:
Hiroshi Takaku, Kazuyuki Takai, Shiro Shigeta, Naoko Miyano-Kurosaki, Masatoshi Fujiwara, Takayuki Abe, Tadashi Mizuta, Toshifumi Hatta, Tomoyuki Yokota
Publikováno v:
European Journal of Pharmaceutical Sciences. 13:61-69
The liposomally encapsulated and the free antisense phosphorothioate oligonucleotides (S-ODNs) with four target sites (PB1, PB2, PA, and NP) were tested for their abilities to inhibit virus-induced cytopathogenic effects by a MTT assay using MDCK cel
Autor:
Kiyoko Tomita, Shiro Shigeta, Kazufumi Kimura, Kouei Ohno, Shuichi Mori, Kazuo Takahashi, Masaki Terada
Publikováno v:
Antiviral Research. 47:41-51
NMSO3, a sulfated sialyl lipid was evaluated for its efficacy against respiratory syncytial virus (RSV) and other myxovirus infections in cell culture. The median effective concentration (50% effective concentration, EC(50)) of NMSO3 against replicat
Autor:
Shiro Shigeta
Publikováno v:
Expert Opinion on Investigational Drugs. 9:221-235
The recent progress in antiviral chemotherapy against respiratory syncytial virus (RSV) infections was reviewed. RSV infections among high risk individuals, such as premature babies, infants with congenital disease of cardiopulmonary system or immune
Autor:
Shuichi Mori, Eiichi Kodama, Kazuo Takahashi, Mineo Saneyoshi, Shiro Shigeta, T Wakayama, T. Kira, T Nagata, N Koike, H Kato, K Konno
Publikováno v:
Antiviral Chemistry and Chemotherapy. 10:195-209
Twenty 2-thiopyrimidine nucleoside analogues were synthesized and examined for inhibitory activity against herpes simplex virus (HSV) type 1 and 2, varicella-zoster virus (VZV), human cytomegalovirus (HCMV) and thymidine kinase-deficient HSV (HSV-TK)