Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Shiro Morimoto"'
Low-density lipoprotein (LDL) is a well-known causal factor in the development of arteriosclerosis. In the present study, we evaluated LDL-evoked cellular signal transduction in cultured rat vascular smooth muscle cells (VSMC). The addition of LDL at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::693849a0355c390120937ce9adac34e6
https://doi.org/10.1159/000420133
https://doi.org/10.1159/000420133
Autor:
Toshio Ogihara, K. Fukuo, Eio Koh, Y. Miyashita, Shunji Imanaka, Shoichi Kitano, M. Imaoka, Shiro Morimoto
Renal handling of Na and Ca in response to physiological saline infusion (20 ml/kg i.v. for 2 h) was compared between 27 hypertensive (mean +/- SD age 79.8 +/- 9.2 years) and 44 normotensive (79.1 +/- 4.1 years) senile females. Compared to the normot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0968be7dd116dbc039c148ec1ffefa7
https://doi.org/10.1159/000420129
https://doi.org/10.1159/000420129
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 24:487-491
SUMMARY 1. The effects of sarafotoxin S6c (S6c), a selective endothelin ETB receptor agonist, on renal haemodynamics and urine formation were examined in anaesthetized dogs. 2. Intrarenal arterial infusion of S6c at a rate of 1 or 5 ng/kg per min pro
Publikováno v:
European Journal of Pharmacology. 321:195-200
Renal hemodynamic and excretory responses to (+/-)-(E)-4-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (FK409), a novel nitric oxide (NO) donor, were examined using anesthetized rats. When FK409 was infused into the renal artery of normal rats at 1
Autor:
Yasuo Matsumura, Shiro Morimoto, Yasunori Suzuki, Masanori Takaoka, Toshiyoshi Umekawa, Kazutaka Hayashi
Publikováno v:
Journal of Cardiovascular Pharmacology. 28:278-284
The effects of endothelin-3 (ET-3) on changes in renal hemodynamics, urine formation, and norepinephrine (NE) overflow induced by renal nerve stimulation (RNS) were examined in anesthetized dogs. RNS at a low frequency (0.5-2.0 Hz) produced significa
Publikováno v:
Life Sciences. 58:1067-1074
Incubation of cultured porcine aortic endothelial cells (ECs) with plasmin resulted in a significant and concentration-dependent increase in endothelin-1 (ET-1 ) release from the cells. This increasing effect was completely inhibited by aprotinin but
Publikováno v:
Journal of Cardiovascular Pharmacology. 27:211-217
To investigate the role of nitric oxide (NO) in the regulation of renal sympathetic nerve activity and renal function, we examined the effect of sodium nitroprusside (SNP), a NO donor, on renal actions induced by renal nerve stimulation (RNS) in anes
Autor:
Yasuo Matsumura, Katsuya Fujita, Yohko Miyazaki, Shiro Morimoto, Norio Hashimoto, Masanori Takaoka
Publikováno v:
Life Sciences. 58:PL1-PL7
Renal effects of FR139317, an endothelin ETA receptor antagonist, were examined using anesthetized normotensive and deoxycorticosterone acetate (DOCA)-salt hypertensive rats. The intravenous bolus injection of FR139317 (10 mg/kg) produced a slight de
Publikováno v:
European Journal of Pharmacology. 280:311-316
We examined the effect of long-term nitric oxide (NO) synthase inhibition on vascular and renal endothelin-1 levels and evaluated the antihypertensive effect of endothelin ETA receptor antagonist FR139317 ((R)2(-)[(R)-2(-)[(S)-2(-)[[1-(hexahydro-1H-a
Publikováno v:
Journal of Cardiovascular Pharmacology. 25:187-193
We examined the effects of NG-nitro-L-arginine (NOARG) on antidiuresis and norepinephrine (NE) overflow in anesthetized dogs, induced by renal nerve stimulation (RNS), with or without blockade of an action of endogenous angiotensin II (AII) on the AT