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Akademický článek

Two cases of acute‐onset cystoid macular edema and serous retinal detachment associated with combined use of encorafenib and binimetinib for advanced melanoma: A possible confounding risk for drug intolerance

Autor: Takumi Hasegawa, Shiro Iino, Misako Fujisaki, Sayuri Okamura, Natsuki Baba, Nami Tanaka, Yuko Takeuchi, Noritaka Oyama, Minoru Hasegawa

Publikováno v: Journal of Cutaneous Immunology and Allergy, Vol 6, Iss 6, Pp 231-233 (2023)

Abstract While combined use of BRAF/MEK inhibitors has elicited dramatic clinical efficacy in incurable melanoma, drug‐associated retinopathy has become an emerging adverse event. We present two Japanese men with advanced melanoma who developed vis

Externí odkaz: https://doaj.org/article/bb4af40162b643dfa7e29d30ab02af2e

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Akademický článek

Retrospective evaluation of the utility of two-step surgery for facial basal cell carcinoma and squamous cell carcinoma

Autor: Shiro Iino, Natsuki Baba, Takumi Hasegawa, Hiroshi Kasamatsu, Noritaka Oyama, Takahiro Tokunaga, Minoru Hasegawa

Publikováno v: Frontiers in Surgery, Vol 9 (2022)

In older patients with facial basal cell carcinoma (BCC) or squamous cell carcinoma (SCC), surgery should be aimed to reduce treatment-related sequelae and burden with achieving local tumor care. Therefore, we adopted a two-step surgery (TSS) involvi

Externí odkaz: https://doaj.org/article/db0836913c7b43849a39ff106c527b44

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Akademický článek

A Case of Erythema Multiforme Major Developed after Sequential Use of Two Immune Checkpoint Inhibitors, Nivolumab and Ipilimumab, for Advanced Melanoma: Possible Implication of Synergistic and/or Complementary Immunomodulatory Effects

Autor: Akira Utsunomiya, Noritaka Oyama, Shiro Iino, Natsuki Baba, Takenao Chino, Natsuko Utsunomiya, Minoru Hasegawa

Publikováno v: Case Reports in Dermatology, Vol 10, Iss 1, Pp 1-6 (2018)

Immune checkpoint inhibitors, such as ipilimumab and nivolumab, reverse the imbalance of antitumor self-tolerance and enhance T-cell responses. Currently, ipilimumab and nivolumab have a reported therapeutic impact on unresectable or metastatic melan

Externí odkaz: https://doaj.org/article/f7e24a47aab74697bea91e1630fc01b5

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A rare case of eosinophilic gastritis induced by nivolumab therapy for metastatic melanoma

Autor: Arisa Tsuji, Katsushi Hiramatsu, Shouichi Namikawa, Arisa Yamamoto, Yohei Midori, Yosuke Murata, Tomoko Tanaka, Takuto Nosaka, Tatsushi Naito, Kazuto Takahashi, Kazuya Ofuji, Hidetaka Matsuda, Masahiro Ohtani, Yoshiaki Imamura, Shiro Iino, Minoru Hasegawa, Yasunari Nakamoto

Publikováno v: Clinical Journal of Gastroenterology. 15:876-880

Cancer immunotherapy using immune checkpoint inhibitors can cause immune reactions at various sites as a side effect called immune-related adverse events (irAEs). The gastrointestinal tract is susceptible to irAEs, however, the degree and presentatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b57d0b86585f4aac9e4127dddb0a494
https://doi.org/10.1007/s12328-022-01680-y

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Narrower clinical margin in high or very high‐risk squamous cell carcinoma: a retrospective, multicenter study of 1,000 patients

Publikováno v: JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 20:1088-1099

In cutaneous squamous cell carcinoma (cSCC), adherence to guideline-recommended fixed surgical margins is often difficult, and narrower margins are preferable. This study aimed to evaluate relapse and disease-specific death with narrower margins for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f37be5158b5aef675659d8f2a8579c34
https://doi.org/10.1111/ddg.14810

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Long‐standing refractory hidradenitis suppurativa responded to a brodalumab monotherapy in a patient with psoriasis: A possible involvement of Th17 across the spectrum of both diseases

Autor: Yasuyuki Yoshida, Noritaka Oyama, Minoru Hasegawa, Chihiro Shimizu, Shiro Iino

Publikováno v: The Journal of Dermatology. 48:916-920

Hidradenitis suppurativa (HS), also known as acne inversa, is a chronic inflammatory skin disease mainly affecting apocrine gland-rich areas of the body with painful nodules, persisted abscess, sinus tracts, and scarring. The etiopathology of HS rema

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1674650469b33100698a65a7bc05309d
https://doi.org/10.1111/1346-8138.15807

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