Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Shiro Aizawa"'
Autor:
Yoko Hirabayashi, Fumiko Watanabe, Sachiko Wada, Keiko Watanabe, Kazuko Yoshida, Tohru Inoue, Shiro Aizawa
Publikováno v:
Radiation Research. 167(6):703-710
Mice exposed to a lethal dose of radiation were repopulated with heterozygous p53(+/-) (TRP53(+/-)) bone marrow cells and then exposed to doses of 1, 3 and 5 Gy 1 month later. This resulted in the transplanted bone marrow-specific diseases other than
Publikováno v:
International Journal of Radiation Biology. 83(4):259-267
Purpose: The appearance of tumor suppressor protein 53 (p53) -/- thymocytes at an early stage of radiation-induced lymphomagenesis was investigated in the p53 heterozygous (+/-) B10 mice following a single dose of irradiation, since most thymic lymph
Autor:
Masanobu Kitagawa, Kaoru Tanaka, Shiro Aizawa, Kazuko Yoshida, Kouichi Tatsumi, Yuko Noda, Maki Hasegawa, Shuichi Yamaguchi, Katsuiku Hirokawa
Publikováno v:
Leukemia Research. 29(3):307-316
Friend leukemia virus (FLV) infection strongly enhances γ-irradiation-induced apoptosis of hematopoietic cells of C3H hosts leading to a lethal anemia. Experiments using p53 knockout mice with the C3H background have clarified that the apoptosis is
Publikováno v:
Leukemia Research. 26:1085-1092
C3H/He mice produce myeloid leukemias after whole body irradiation of 1–3 Gy as compared with non-irradiated controls that produce fewer than 1% of leukemia [Radiatiton Research 127 (1991) 146]. Thus, p53-deficient C57BL/6 strain, a malignant lymph
Autor:
Masanobu Kitagawa, Toshihiko Sado, Katsuiku Hirokawa, Kaoru Tanaka, Maki Hasegawa, Shiro Aizawa, Shuichi Yamaguchi
Publikováno v:
Journal of Virology. 76:7790-7798
Exposure of hematopoietic progenitors to gamma irradiation induces p53 -dependent apoptosis. However, host responses to DNA damage are not uniform and can be modified by various factors. Here, we report that a split low-dose total-body irradiation (T
Autor:
Kimio Tanaka, Masahiko Mori, H. Tsuji, Shiro Aizawa, Kazuko Yoshida, Keiko Watanabe, Tohru Inoue, Yoko Hirabayashi, Hitoko Kamisaku
Publikováno v:
International Journal of Radiation Biology. 78:165-172
Cellular and cytogenetic events in radiation-induced thymic lymphomagenesis were investigated in the p53 heterozygous (+/-) mouse following a single dose of whole-body irradiation.The loss of the wild-type p53 allele and microsatellite markers of chr
Autor:
Hidetoshi Ikeda, Sayaka Takase-Yoden, Takako Suzuki, Rihito Watanabe, Yutaka Matsubara, Shiro Aizawa, Hiroshi Kitani, Kanako Kato, Masanobu Kitagawa
Publikováno v:
Journal of Virology. 74:1815-1826
Ecotropic murine leukemia virus (MuLV) infection is initiated by the interaction between the surface glycoprotein (SU) of the virus and its cell-surface receptor mCAT-1. We investigated the SU-receptor interaction by using a naturally occurring solub
Publikováno v:
International Journal of Radiation Biology. 76:1105-1111
B10 strain mice are susceptible to the induction of thymic lymphomas by fractionated whole-body X-irradiation (FI), whereas C3H and STS mice are resistant. The nature of the factors responsible for the strain difference in the susceptibility to thymi
Publikováno v:
Transplantation. 65:893-898
We previously indicated that intensity of the graft-versus-leukemia (GVL) effect varied among different leukemias in MHC-compatible, allogeneic bone marrow transplantation (BMT). Cellular factors responsible for differences in intensity of the GVL ef
Publikováno v:
Pathology International. 46:719-725
Resistance to retroviral infection is often regulated by multiple genes that control different aspects of the host-virus interaction. Genetically distinct inbred strains of mice differ in their susceptibility to retrovirus and have allowed the identi