Zobrazeno 1 - 10
of 178
pro vyhledávání: '"Shirng Wern Tsaih"'
Autor:
Anjali Geethadevi, Zhiqiang Ku, Shirng-Wern Tsaih, Deepak Parashar, Ishaque P. Kadamberi, Wei Xiong, Hui Deng, Jasmine George, Sudhir Kumar, Sonam Mittal, Ningyan Zhang, Sunila Pradeep, Zhiqiang An, Pradeep Chaluvally-Raghavan
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract Chemotherapy such as cisplatin is widely used to treat ovarian cancer either before or after surgical debulking. However, cancer relapse due to chemotherapy resistance is a major challenge in the treatment of ovarian cancer. The underlying m
Externí odkaz:
https://doaj.org/article/ef81d450abe040d3a9700614472c2f15
Autor:
Roshan Kumar, Marissa Iden, Shirng-Wern Tsaih, Rachel Schmidt, Akinyemi I. Ojesina, Janet S. Rader
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Cervical cancer remains a significant health challenge for women worldwide, with a disproportionate impact on developing regions like sub-Saharan Africa. Taking advantage of recent advancements in developing suitable preclinical models to study cell
Externí odkaz:
https://doaj.org/article/4be3415c744a4e9eb91c0e9b20cb6b7a
Autor:
Rachel Cusatis, Colin Johnson, Katherine D. Schoyer, Shirng-Wern Tsaih, Joanna Balza, Jay Sandlow, Kathryn E. Flynn
Publikováno v:
Reproductive Health, Vol 20, Iss 1, Pp 1-13 (2023)
Abstract Background Decisions for how to resolve infertility are complex and may lead to regret. We examined whether couples and individuals who sought a consultation from a reproductive specialist for infertility later expressed decisional regret ab
Externí odkaz:
https://doaj.org/article/c1030ff89fc84b2e83cdf9d580adac6c
Autor:
Sonam Mittal, Ishaque Pulikkal Kadamberi, Hua Chang, Feng Wang, Sudhir Kumar, Shirng-Wern Tsaih, Christopher J. Walker, Pradeep Chaluvally-Raghavan, John Charlson, Yosef Landesman, Sunila Pradeep
Publikováno v:
Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-6 (2023)
Abstract Leiomyosarcoma (LMS) is a rare soft tissue sarcoma (STS) that begins in smooth muscle tissue and most often initiates in the abdomen or uterus. Compared with other uterine cancers, uterine LMS (ULMS) is an aggressive tumor with poor prognosi
Externí odkaz:
https://doaj.org/article/91fda5397a8d4c568f9244b8871df4be
Publikováno v:
Molecular Medicine, Vol 29, Iss 1, Pp 1-12 (2023)
Abstract Background Neuronatin (NNAT) was recently identified as a novel mediator of estrogen receptor-positive (ER+) breast cancer cell proliferation and migration, which correlated with decreased tumorigenic potential and prolonged patient survival
Externí odkaz:
https://doaj.org/article/f7cb67d9f1ff47ecbff12c988d02021d
Autor:
Bridget Riley-Gillis, Shirng-Wern Tsaih, Emily King, Sabrina Wollenhaupt, Jonas Reeb, Amy R. Peck, Kelsey Wackman, Angela Lemke, Hallgeir Rui, Zoltan Dezso, Michael J. Flister
Publikováno v:
iScience, Vol 26, Iss 9, Pp 107576- (2023)
Summary: Heritability in the immune tumor microenvironment (iTME) has been widely observed yet remains largely uncharacterized. Here, we developed a machine learning approach to map iTME modifiers within loci from genome-wide association studies (GWA
Externí odkaz:
https://doaj.org/article/c7ce89221a684130966eeb85e931f3cc
Autor:
Jasmine George, Yongsheng Li, Ishaque P. Kadamberi, Deepak Parashar, Shirng-Wern Tsaih, Prachi Gupta, Anjali Geethadevi, Changliang Chen, Chandrima Ghosh, Yunguang Sun, Sonam Mittal, Ramani Ramchandran, Hallgeir Rui, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Gustavo Leone, Janet S. Rader, Anil K. Sood, Madhusudan Dey, Sunila Pradeep, Pradeep Chaluvally-Raghavan
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112228- (2023)
Externí odkaz:
https://doaj.org/article/a5654581f76b41b8a9797d688793a04d
Autor:
Prachi Gupta, Ishaque Pulikkal Kadamberi, Sonam Mittal, Shirng‐Wern Tsaih, Jasmine George, Sudhir Kumar, Dileep K. Vijayan, Anjali Geethadevi, Deepak Parashar, Paytsar Topchyan, Lindsey McAlarnen, Brian F Volkman, Weiguo Cui, Kam Y. J. Zhang, Dolores Di Vizio, Pradeep Chaluvally‐Raghavan, Sunila Pradeep
Publikováno v:
Advanced Science, Vol 9, Iss 14, Pp n/a-n/a (2022)
Abstract SPHK1 (sphingosine kinase‐1) catalyzes the phosphorylation of sphingosine to sphingosine‐1‐phosphate (S1P), is found to be highly expressed in solid tumors. Here, extracellular vesicles (EVs) are identified as the key transporters of S
Externí odkaz:
https://doaj.org/article/f06bbfca07794a258533a5731cd75e20
Autor:
Jasmine George, Yongsheng Li, Ishaque P. Kadamberi, Deepak Parashar, Shirng-Wern Tsaih, Prachi Gupta, Anjali Geethadevi, Changliang Chen, Chandrima Ghosh, Yunguang Sun, Sonam Mittal, Ramani Ramchandran, Hallgeir Rui, Gabriel Lopez-Berestein, Cristian Rodriguez-Aguayo, Gustavo Leone, Janet S. Rader, Anil K. Sood, Madhusudan Dey, Sunila Pradeep, Pradeep Chaluvally-Raghavan
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109934- (2021)
Summary: Fragile X-related protein-1 (FXR1) gene is highly amplified in patients with ovarian cancer, and this amplification is associated with increased expression of both FXR1 mRNA and protein. FXR1 expression directly associates with the survival
Externí odkaz:
https://doaj.org/article/1bda5605c1c8465997ff1e6038dd99f9
Autor:
Kevin D. Wright, Bradley S. Miller, Sarah El-Meanawy, Shirng-Wern Tsaih, Anjishnu Banerjee, Aron M. Geurts, Yuri Sheinin, Yunguang Sun, Balaraman Kalyanaraman, Hallgeir Rui, Michael J. Flister, Andrey Sorokin
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-12 (2019)
Abstract Background SHC1 proteins (also called SHCA) exist in three functionally distinct isoforms (p46SHC, p52SHC, and p66SHC) that serve as intracellular adaptors for several key signaling pathways in breast cancer. Despite the broad evidence impli
Externí odkaz:
https://doaj.org/article/38936579b97f4f199df72a29402941f9