Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Shirly Becker-Herman"'
Autor:
Stav Rabani, Emine Gulsen Gunes, Martin Gunes, Bianca Pellegrino, Bar Lampert, Keren David, Raju Pillai, Aimin Li, Shirly Becker-Herman, Steven T. Rosen, Idit Shachar
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114920- (2024)
Summary: Triple-negative breast cancer (TNBC) is the most aggressive breast cancer subtype. The tumor microenvironment (TME) plays a major regulatory role in TNBC progression and is highly infiltrated by suppressive immune cells that reduce anti-tumo
Externí odkaz:
https://doaj.org/article/07986e34a7fa4417aebf0d3aa8f5f5cf
Autor:
Hadas Lewinsky, Emine G. Gunes, Keren David, Lihi Radomir, Matthias P. Kramer, Bianca Pellegrino, Michal Perpinial, Jing Chen, Ting-fang He, Anthony G. Mansour, Kun-Yu Teng, Supriyo Bhattacharya, Enrico Caserta, Estelle Troadec, Peter Lee, Mingye Feng, Jonathan Keats, Amrita Krishnan, Michael Rosenzweig, Jianhua Yu, Michael A. Caligiuri, Yosef Cohen, Olga Shevetz, Shirly Becker-Herman, Flavia Pichiorri, Steven Rosen, Idit Shachar
Publikováno v:
JCI Insight, Vol 8, Iss 14 (2023)
Externí odkaz:
https://doaj.org/article/fac6727535924d42be070993ae2438ba
Autor:
Ariel Ogran, Tal Havkin-Solomon, Shirly Becker-Herman, Keren David, Idit Shachar, Rivka Dikstein
Publikováno v:
eLife, Vol 11 (2022)
The transformation of normal to malignant cells is accompanied by substantial changes in gene expression programs through diverse mechanisms. Here, we examined the changes in the landscape of transcription start sites and alternative promoter (AP) us
Externí odkaz:
https://doaj.org/article/4a07f29a457d4718a1b3bfb50f6d062c
Autor:
Lihi Radomir, Matthias P. Kramer, Michal Perpinial, Nofar Schottlender, Stav Rabani, Keren David, Anna Wiener, Hadas Lewinsky, Shirly Becker-Herman, Rina Aharoni, Ron Milo, Claudia Mauri, Idit Shachar
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Regulatory B (Breg) cells suppress excessive inflammation primary via the production of interleukin 10 (IL-10). Here the authors show that the function and homeostasis of mouse and human IL-10+ Breg cells are negatively regulated by the cell surface
Externí odkaz:
https://doaj.org/article/9e0225d58b0f4b71aa42bed1e5fd6e18
Autor:
Shirly Becker-Herman, Milena Rozenberg, Carmit Hillel-Karniel, Naama Gil-Yarom, Mattias P Kramer, Avital Barak, Lital Sever, Keren David, Lihi Radomir, Hadas Lewinsky, Michal Levi, Gilgi Friedlander, Richard Bucala, Amnon Peled, Idit Shachar
Publikováno v:
PLoS Biology, Vol 19, Iss 3, p e3001121 (2021)
Hematopoietic stem and progenitor cells (HSPCs) are a small population of undifferentiated cells that have the capacity for self-renewal and differentiate into all blood cell lineages. These cells are the most useful cells for clinical transplantatio
Externí odkaz:
https://doaj.org/article/31d2b909abae4ae2830454e4fdbfdedf
Autor:
Hadas Lewinsky, Emine G. Gunes, Keren David, Lihi Radomir, Matthias P. Kramer, Bianca Pellegrino, Michal Perpinial, Jing Chen, Ting-fang He, Anthony G. Mansour, Kun-Yu Teng, Supriyo Bhattacharya, Enrico Caserta, Estelle Troadec, Peter Lee, Mingye Feng, Jonathan Keats, Amrita Krishnan, Michael Rosenzweig, Jianhua Yu, Michael A. Caligiuri, Yosef Cohen, Olga Shevetz, Shirly Becker-Herman, Flavia Pichiorri, Steven Rosen, Idit Shachar
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
Multiple myeloma (MM) is characterized by an accumulation of malignant plasma cells (PCs) within the BM. The BM microenvironment supports survival of the malignant cells and is composed of cellular fractions that foster myeloma development and progre
Externí odkaz:
https://doaj.org/article/d7a411db996948a2b5bdffc9677fbefe
Autor:
Keren David, Gilgi Friedlander, Bianca Pellegrino, Lihi Radomir, Hadas Lewinsky, Lin Leng, Richard Bucala, Shirly Becker-Herman, Idit Shachar
Publikováno v:
Cell Reports. 41:111572
CD74 is receptor for the cytokine macrophage migration inhibitory factor (MIF). MIF binding to CD74 induces a signaling cascade resulting in the release of its cytosolic intracellular domain (CD74-ICD) that serves as a transcriptional regulator in ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::101baa19eeb07884576b8ae81058231e
https://doi.org/10.1016/j.celrep.2022.111572
https://doi.org/10.1016/j.celrep.2022.111572
Autor:
Shirly Becker-Herman, Keren David, Michal Perpinial, Hadas Lewinsky, Ron Milo, Anna Wiener, Claudia Mauri, Rina Aharoni, Nofar Schottlender, Lihi Radomir, Idit Shachar, Matthias P. Kramer, Stav Rabani
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
B cells have essential functions in multiple sclerosis and in its mouse model, experimental autoimmune encephalomyelitis, both as drivers and suppressors of the disease. The suppressive effects are driven by a regulatory B cell (Breg) population that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d2082394f3fa1fba4da56deb528acca
https://doi.org/10.1038/s41467-021-22230-z
https://doi.org/10.1038/s41467-021-22230-z
Autor:
Amrita Krishnan, Michael Rosenzweig, Supriyo Bhattacharya, Mingye Feng, Kun Yu Teng, Jonathan J. Keats, Lihi Radomir, Enrico Caserta, Idit Shachar, Hadas Lewinsky, Michal Perpinial, Shirly Becker-Herman, Yosef Cohen, Ting-Fang He, Steven D. Rosen, Olga Shevetz, Flavia Pichiorri, Estelle Troadec, Keren David, Michael A. Caligiuri, Peter P. Lee, Jing Chen, Matthias P. Kramer, Anthony Mansour, Jianhua Yu, Emine Gulsen Gunes, Bianca Pellegrino
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
JCI Insight
JCI Insight
Multiple myeloma (MM) is characterized by an accumulation of malignant plasma cells (PCs) within the BM. The BM microenvironment supports survival of the malignant cells and is composed of cellular fractions that foster myeloma development and progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ff3899d3875798127061e3c699753b2
https://doaj.org/article/d7a411db996948a2b5bdffc9677fbefe
https://doaj.org/article/d7a411db996948a2b5bdffc9677fbefe