Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Shirley Xu"'
Autor:
Liang Hu, Shiming Zhang, John Sienkiewicz, Hua Zhou, Robert Berahovich, Jinying Sun, Michael Li, Adrian Ocampo, Xianghong Liu, Yanwei Huang, Hizkia Harto, Shirley Xu, Vita Golubovskaya, Lijun Wu
Publikováno v:
Vaccines, Vol 12, Iss 7, p 808 (2024)
The human epidermal growth factor receptor 2 (HER2) is a transmembrane tyrosine kinase receptor and tumor-associated antigen abnormally expressed in various types of cancer, including breast, ovarian, and gastric cancer. HER2 overexpression is highly
Externí odkaz:
https://doaj.org/article/5e9fef36bc994280ab60b2abc79c145c
Autor:
Paul S. Kwon, Shirley Xu, Hanseul Oh, Seok-Joon Kwon, Andre L. Rodrigues, Maisha Feroz, Keith Fraser, Peng He, Fuming Zhang, Jung Joo Hong, Robert J. Linhardt, Jonathan S. Dordick
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Suramin, a polysulfated synthetic drug, binds to the ACE2 receptor and heparan sulfate binding sites on SARS-CoV-2 RBDs with preferential binding for Omicron RBD and inhibition of infection by the Omicron variant in vitro.
Externí odkaz:
https://doaj.org/article/f9c4ce0ff01c4a649d774200f246e2fd
Autor:
Shirley Xu, David Perkins
Publikováno v:
IEEE Access, Vol 10, Pp 115869-115883 (2022)
The Closest String Problem (CSP) is an NP-Complete problem which seeks to find the geometrical center of a set of input strings: given $k$ strings of length $L$ and a non-negative integer $d$ , construct a solution string $t$ , if it exists, such tha
Externí odkaz:
https://doaj.org/article/72cf20552d524234b567ab1bba023593
Autor:
Swati D. Sonkawade, Shirley Xu, Minhyung Kim, Sarmila Nepali, Victoire-Grace Karambizi, Sandra Sexton, Steven G. Turowski, Kunpeng Li, Joseph A. Spernyak, Jonathan F. Lovell, Anthony George, Sujit Suwal, Umesh C. Sharma, Saraswati Pokharel
Publikováno v:
Cells, Vol 12, Iss 12, p 1589 (2023)
Background: Cardioprotective effects of N-acetyl-ser-asp-lys-pro (Ac-SDKP) have been reported in preclinical models of myocardial remodeling. However, the rapid degradation of this endogenous peptide in vivo limits its clinical use. Method: To prolon
Externí odkaz:
https://doaj.org/article/5d1e6d7baa66477393818bb394aeef47
Autor:
Kriti Kapil, Shirley Xu, Inseon Lee, Hironobu Murata, Seok-Joon Kwon, Jonathan S. Dordick, Krzysztof Matyjaszewski
Publikováno v:
Polymers, Vol 15, Iss 12, p 2723 (2023)
Infectious diseases caused by pathogens are a health burden, but traditional pathogen identification methods are complex and time-consuming. In this work, we have developed well-defined, multifunctional copolymers with rhodamine B dye synthesized by
Externí odkaz:
https://doaj.org/article/44e0573cdad54635bf5884718dbbbc8a
Autor:
Li-Sheng Wang, Shirley Xu, Sneha Gopal, Eunsol Kim, Domyoung Kim, Matthew Brier, Kusum Solanki, Jonathan S. Dordick
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In situ generation of antibacterial and antiviral agents by harnessing the catalytic activity of enzymes on surfaces provides an effective eco-friendly approach for disinfection. The perhydrolase (AcT) from Mycobacterium smegmatis catalyzes
Externí odkaz:
https://doaj.org/article/f64f9a76d16c46ce93991347d097aebd
Autor:
Xin Li, Robert Berahovich, Hua Zhou, Xianghong Liu, Feng Li, Shirley Xu, Yuehua Wei, Djamila Ouaret, Walter Bodmer, Lijun Wu, Vita Golubovskaya
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 9, Pp 1765-1786 (2020)
Placental alkaline phosphatase, PLAP encoded by ALPP gene in humans is mainly expressed in placenta and testis, and not expressed in any other normal tissues. PLAP is overexpressed in colorectal cancers which makes it an attractive target for CAR (ch
Externí odkaz:
https://doaj.org/article/5bfdc71ff5d94eb9bc0e7c838cc4f713
Autor:
Michael Valentine, Le Li, Hua Zhou, Shirley Xu, Jinying Sun, Chengjing Liu, Hizkia Harto, Robert Berahovich, Vita Golubovskaya, Lijun Wu
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 25, Iss 2, Pp 270-282 (2020)
Chimeric antigen receptor (CAR) T cell immunotherapy has demonstrated clinical success in treatment of B-cell hematologic cancers. In this study, we compared human Transferrin epitope tagged CAR-T cells with non-tagged CAR-T cells for cytotoxicity, I
Externí odkaz:
https://doaj.org/article/687fefd540d744319cd8c15256868f67
Autor:
Eric Galbraith, William Fajzel, Shirley Xu, Veronica Xia, Elena Frie, Christopher Barrington-Leigh, Victoria Reyes-García
Publikováno v:
PLoS ONE, Vol 17, Iss 7, p e0270583 (2022)
Time use studies quantify what people do, over particular time intervals. The results of these studies have illuminated diverse and important aspects of societies and economies, from populations around the world. Yet, these efforts have advanced in a
Externí odkaz:
https://doaj.org/article/8831fbf759b64ee4b808fe07fc44059a
Autor:
Umesh C. Sharma, Swati D. Sonkawade, Andrew Baird, Min Chen, Shirley Xu, Sandra Sexton, Anurag K. Singh, Adrienne Groman, Steven G. Turowski, Joseph A. Spernyak, Supriya D. Mahajan, Saraswati Pokharel
Publikováno v:
Cardio-Oncology, Vol 4, Iss 1, Pp 1-14 (2018)
Abstract Background Cancer survivors treated with thoracic ionizing radiation are at higher risk of premature death due to myocardial ischemia. No therapy is currently available to prevent or mitigate these effects. We tested the hypothesis that an e
Externí odkaz:
https://doaj.org/article/5f16c7bc9a434402adff2aa1fdd3c689