Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shirley P. Levine"'
Autor:
T. Andrew Albritton, Meenakshy Aiyer, Shirley P. Levine, Paul A. Hemmer, Shalini Reddy, Lynne Meyer
Publikováno v:
Southern Medical Journal. 95:1389-1395
Background.Although evidence-based medicine (EBM) has become widely accepted, the extent of its implementation during clinical clerkships is not well described. This study was done to characterize the implementation of formal EBM curricula in interna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85f69fc3f5b04d80b73efc4b5afdeec3
https://doi.org/10.1097/00007611-200212000-00007
https://doi.org/10.1097/00007611-200212000-00007
Publikováno v:
Journal of Laboratory and Clinical Medicine. 129:364-375
We report studies on a new patient with gray platelet syndrome (GPS, alpha-storage pool deficiency). Her lifelong bleeding history is associated with platelet abnormalities characteristic of GPS including mild to moderate thrombocytopenia, a populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49f0e15afc8c3592fd08d6bed1a1dbf
https://doi.org/10.1016/s0022-2143(97)90185-2
https://doi.org/10.1016/s0022-2143(97)90185-2
Publikováno v:
Blood. 75:902-910
Platelet factor 4 (PF4) is a hydrophobic, alpha-granule protein with potent antiheparin activity. It also binds to a chondroitin sulfate- containing proteoglycan (PG) isolated from platelets. In order to evaluate further the relationship between PF4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::720b72be6905666f35fb830a59123e8c
https://doi.org/10.1182/blood.v75.4.902.902
https://doi.org/10.1182/blood.v75.4.902.902
Publikováno v:
Journal of the American Society of Nephrology : JASN. 7(7)
Platelet factor 4(PF4), an abundant platelet secretory product, is a strong candidate for modulating glomerular pathology. Because PF4 might be released from platelets and influence intrinsic cell growth during glomerular injury, the effect of PF4 on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b47c72d9c3300f76456b0eabb6478c
https://pubmed.ncbi.nlm.nih.gov/8829113
https://pubmed.ncbi.nlm.nih.gov/8829113
Publikováno v:
The Journal of Immunology. 123:2835-2841
Basophil-derived platelet activating factor (PAF) was shown to induce the release of platelet factor 4 (PF4), a specific platelet protein, from isolated, washed rabbit platelets. The kinetics and dose response of this release were similar to that of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47117ad1331fc9752050e9961a02c9d
https://doi.org/10.4049/jimmunol.123.6.2835
https://doi.org/10.4049/jimmunol.123.6.2835
Autor:
Shirley P. Levine, Marc A. Shuman
Publikováno v:
Journal of Clinical Investigation. 65:307-313
We have studied the effects of both impaired prothrombin activation and direct inhibition of thrombin on the platelet release reaction in clotting blood to determine the role of thrombin in this process. In blood from two patients with congenital Fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51416a3cb19b1759cce42f68883dbdf4
https://doi.org/10.1172/jci109673
https://doi.org/10.1172/jci109673
Autor:
Shirley P. Levine, Linda S. Krentz
Publikováno v:
Thrombosis Research. 11:673-686
Human platelet factor 4 (PF4), a secreted protein with antiheparin activity, was purified by affinity chromatography on heparinepsilon aminocaproic acid-SepharoseR and used to prepare antibodies in rabbits. The resulting antibodies reacted in immunod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07f7becf1ae726b4dad503d331c449ff
https://doi.org/10.1016/0049-3848(77)90025-1
https://doi.org/10.1016/0049-3848(77)90025-1
Publikováno v:
The Histochemical Journal. 16:983-1001
The distribution of beta-thromboglobulin, platelet factor 4, and fibrinogen in unstimulated platelets was investigated by several immunocytochemical techniques. All three substances were found to be localized in the majority of platelet alpha granule
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07b9701b84349d85c71fb7f16ebd45e9
https://doi.org/10.1007/bf01003853
https://doi.org/10.1007/bf01003853
Autor:
Shirley P. Levine, Brenda L. Towell
Publikováno v:
The American Journal of Medicine. 82:371-375
Massive compensatory hepatic myeloid metaplasia occurs infrequently after splenectomy for myeloid metaplasia, and it usually develops gradually over several years if it does occur. In this report, a patient is described in whom massive hepatomegaly a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3360fbd1d96b1443fb8d350c22404de
https://doi.org/10.1016/0002-9343(87)90091-x
https://doi.org/10.1016/0002-9343(87)90091-x
Publikováno v:
Kidney International. 25:759-765
Binding of platelet factor four (PF 4) to glomerular polyanion. Synthetic polycations have been shown to bind to glomerular polyanion (GPA) and increase glomerular permeability. Here, we show that human platelet factor 4 (PF 4), a platelet secretory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618f1f2976706411112e1698a95688ed
https://doi.org/10.1038/ki.1984.87
https://doi.org/10.1038/ki.1984.87