Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shirley Mihardja"'
Autor:
Shenda Gu, Irene Tang, Shirley Mihardja, Wei Wei Prior, Hieu V. Tran, Allan Chan, Anna McClain, Aaron Kurtzman, Shihao Chen, Youguang Luo, Xiaoyan Kang, Xiaoran Wu, Qingmei Zheng, Guodong Jia
Publikováno v:
Cancer Research. 82:4245-4245
4-1BB (CD137, TNFRSF9) is a potent co-stimulatory receptor found on T and NK cells. Activation of 4-1BB requires receptor clustering, which is naturally mediated by the endogenous trimeric 4-1BB ligand. Cross-linking via agnostic monoclonal antibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b3715e44649446dc7b19df5fe395ce3
https://doi.org/10.1158/1538-7445.am2022-4245
https://doi.org/10.1158/1538-7445.am2022-4245
Autor:
Jie Liu, Shirley Mihardja, Irving L. Weissman, Ravindra Majeti, Jens-Peter Volkmer, Balaji Agoram, Kavitha Sompalli, Sharline Chen, Seethu Xavy, Timothy S Choi, Dongdong Feng
Publikováno v:
JCI Insight
The CD47/signal regulatory protein α (Cd47/SIRPα)interaction provides a macrophage immune checkpoint pathway that plays a critical role in cancer immune evasion across multiple cancers. Here, we report the engineering of a humanized anti-SIRPα mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d47165cdac3a638bd37ce609e8658616
https://pubmed.ncbi.nlm.nih.gov/32427583
https://pubmed.ncbi.nlm.nih.gov/32427583
Autor:
Jonathan B. Houze, Andrea Boden, Ning Li, Dongming M. Liu, Xun Li, Jing Man Wong, Paul John Dransfield, Khanh Nguyen, Sridharan Rajamani, Gayathri Swaminath, Weston Sutherland, Yaping Sun, Ying Zhang, Vatee Pattaropong, Rhonda Chen, Vishnu Chintalgattu, Xiaochuan Ma, Murielle M. Véniant, Jim R. Turk, Ray W. Chui, Jinghong Wang, BaoXi Gao, Mark R. Fielden, Joyce Chi Yee Chan, Hugo M. Vargas, Kimberly M. Hoagland, Yinhong Chen, Yusheng Qu, Aarif Y. Khakoo, Shirley Mihardja, Qi Guo, Brandon Ason, Liaoyuan A. Hu, Ji Ma
Publikováno v:
JCI Insight
Heart failure (HF) remains a grievous illness with poor prognosis even with optimal care. The apelin receptor (APJ) counteracts the pressor effect of angiotensin II, attenuates ischemic injury, and has the potential to be a novel target to treat HF.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3042c04a79fb6373e3d1699adde8eb0a
https://pubmed.ncbi.nlm.nih.gov/32208384
https://pubmed.ncbi.nlm.nih.gov/32208384