Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shirley J. Godwin"'
Publikováno v:
Autonomic Neuroscience. 107:20-31
The present study examined the role of the rostral ventrolateral medulla (RVLM) in mediating the pressor and renal sympathetic baroreflex effects of intraventricularly administered angiotensin II (Ang II) in urethane anaesthetised rabbits. Microinjec
Publikováno v:
Journal of Hypertension. 21:167-178
Objective To determine the involvement of central imidazoline receptors in the cardiovascular actions of the chronically administered antihypertensive agents moxonidine, rilmenidine and clonidine. Design and methods In 21 rabbits with implanted fourt
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 278:H558-H566
The effect of chronic activation or inhibition of central ANG II receptors on cardiac baroreflex function in conscious normotensive rabbits was examined. Animals received a fourth ventricular (4V) infusion of ANG II (30 and 100 ng/h), losartan (3 and
Publikováno v:
Journal of the Autonomic Nervous System. 72:195-204
In 10 conscious rabbits, the baroreceptor–heart rate (HR) reflex effects of centrally acting antihypertensive agents with high affinity for imidazoline receptors (IRs), moxonidine and rilmenidine, were compared with clonidine which acts predominant
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 275:R1174-R1184
In the present study, we examined the effect of blockade of the brain stem renin-angiotensin system on renal sympathetic baroreflexes and chemoreflexes in conscious rabbits and examined the role of central catecholaminergic pathways in these response
Publikováno v:
Pharmacological Research. 34:135-141
Short-term (one week) and chronic (six week) cardiovascular effects of orally administered perindopril were examined in the rabbit to demonstrate if short-term results can predict chronic outcomes. In short-term treatment, five doses of perindopril w
Autor:
Geoffrey A. Head, Roger A. L. Dampney, Shirley J. Godwin, P.D Potts, Yoshitaka Hirooka, Robert D. Bendle
Publikováno v:
Hypertension. 27:287-296
Abstract Previous studies have shown that angiotensin II (Ang II) can activate cardiovascular neurons within the medulla oblongata via an action on specific receptors. The purpose of this study was to determine the distribution of neurons within the
Publikováno v:
Clinical and experimental hypertension (New York, N.Y. : 1993). 19(5-6)
This study examined the possible contribution of the brain renin-angiotensin system on the sympathetic activation induced by hypoxia in conscious rabbits. Blood pressure (BP), heart rate (HR) and renal sympathetic nerve activity (RSNA) were recorded
Publikováno v:
Neurochemistry international. 30(1)
Agmatine, an endogenous clonidine-displacing substance, has been shown to have an affinity for both alpha 2-adrenoceptors and imidazoline receptors (IR). In conscious rabbits, we have examined the cardiovascular effects of agmatine and its interactio
Publikováno v:
Fundamental & Clinical Pharmacology. 11:104s-104s