Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shirley Clift"'
Autor:
Satoshi Takahashi, Reiko Kunisaki, Dale Ando, Noriharu Satoh, Kenzaburo Tani, Richard C. Mulligan, Junko Ohata, Hiroki Yoshikawa, K. Kawai, Miyuki Azuma, Shigetaka Asano, Yukoh Nakazaki, Taira Maekawa, Masazumi Eriguchi, Yusuke Inoue, Hideaki Tahara, Shinji Tomikawa, Yoshitsugu Yamada, Naoki Oyaizu, Arinobu Tojo, Kiyoshi Watari, Hideyuki Akaza, Yasushi Soda, Keisuke Takahashi, Maki Oiwa-Monna, Tadao Kakizoe, Masayuki Noguchi, Aikichi Iwamoto, Koh Okumura, Makoto Fujime, Hidenori Hase, Kisaburo Hanazawa, Yoshiaki Wakumoto, Utako Machida, Hirofumi Hamada, Naohide Yamashita, Shirley Clift
Publikováno v:
Molecular Therapy. 10(4):799-816
We produced lethally irradiated retrovirally GM-CSF-transduced autologous renal tumor cell vaccines (GVAX) from six Japanese patients with stage IV renal cell cancer (RCC). Four patients received GVAX ranging from 1.4 × 108 to 3.7 × 108 cells on 6
Autor:
Cathleen Lynch, Thomas R. Lynch, Shirley Clift, Jean Lukanich, Iain J. Webb, Panos Fidias, David J. Sugarbaker, John C. Wain, Cameron D. Wright, Steve Mentzer, Scott J. Swanson, Ravi Salgia, Michael T. Jaklitsch, Joan Lucca, Richard C. Mulligan, Kenneth Jung, F. Stephen Hodi, Martin C. Mihm, Arthur T. Skarin, Glenn Dranoff, Douglas J. Mathisen, Donna Neuberg, Raphael Bueno, Steve Hardy, Dean M. Donahue
Publikováno v:
Journal of Clinical Oncology. 21:624-630
Purpose: We demonstrated that vaccination with irradiated tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor (GM-CSF) stimulates potent, specific, and long-lasting antitumor immunity in multiple murine models and patie
Autor:
Keisuke Takahashi, Stephan Sherwin, Noriharu Satoh, Shinji Tomikawa, Taro Shuin, Atsuko Masunaga, Reiko Kitamura, Naohide Yamashita, Tomoko Yamazaki, Arinobu Tojo, Hidenori Hase, Kiyoshi Watari, Taira Maekawa, Makoto Fujime, Kisaburo Hanazawa, Shigetaka Asano, Yukoh Nakazaki, Muneomi Endo, Yoshiaki Wakumoto, Miyuki Azuma, Masazumi Eriguchi, K. Kawai, Hirofumi Hamada, Daiki Adachi, Hideyuki Akaza, Richard C. Mulligan, Junko Ohata, Utako Machida, Dale Ando, Koh Okumura, Fumihiko Komine, Yasushi Soda, Maki Oiwa, Shirley Clift, Kenzaburo Tani
Publikováno v:
Cancer Chemotherapy and Pharmacology. 46:S73-S76
There is no effective treatment for patients with stage IV renal cell cancer (RCC), although the introduction of new therapy is imminent. Cancer gene therapy is currently considered to be one of the most promising therapeutic modalities in the field
Autor:
Robert J. Soiffer, A Berns, Arthur J. Sober, T Lynch, R P Johnson, K Jung, P Lam, L Richards, Richard C. Mulligan, Gordon Parry, L Liebster, K Kolesar, Atul K. Bhan, J Rokovich, Martin Mihm, Shirley Clift, J Drayer, Rosemary B. Duda, Kenneth K. Tanabe, Samuel Singer, Glenn Dranoff, Lawrence K. Cohen, Steven J. Mentzer
Publikováno v:
Human Gene Therapy. 8:111-123
Autor:
Principal InvestigatorJonathan W. Simons, Richard C. Mulligan, William G. Nelson, Gordon Parry, Alan H. Partin, Hyam I. Levitsky, Investigators: Anton J. M. Berns, Lawrence K. Cohen, James Zabora, Audrey J. Lazenby, Glenn Dranoff, Drew M. Pardoll, Fray F. Marshall, Shirley Clift, Elizabeth M. Jaffee, Karen M. Hauda, Jonathan W. Simons, Ross C. Donehower, Steven Piantadosi, Albert H. Owens
Publikováno v:
Human Gene Therapy. 6:347-368
Autor:
Robert J. Soiffer, Steve Hardy, Frank G. Haluska, Kenneth Jung, Raphael Bueno, Silke Gillessen, Rosemary B. Duda, Steven J. Mentzer, Kenneth K. Tanabe, Samuel Singer, Shirley Clift, Donna Neuberg, Richard C. Mulligan, Glenn Dranoff, F. Stephen Hodi, Martin C. Mihm, Iain J. Webb, Michael T. Jaklitsch
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 21(17)
Purpose: Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor (GM-CSF) by retroviral-mediated gene transfer generates potent antitumor immunity in patients with metastatic melan
Autor:
Shigetaka Asano, Masazumi Eriguchi, Shirley Clift, Hideyuki Akaza, Makoto Fujime, Dale Ando, Naohide Yamashita, Ko Okumura, Shinji Tomikawa, Atsusi Yamauchi, Richard C. Mulligan, Tadao Kakizoe, Masayuki Noguchi, Kenzaburo Tani, Koji Kawai
Publikováno v:
International journal of urology : official journal of the Japanese Urological Association. 9(8)
A phase I study of granulocyte-macrophage colony-stimulating factor (GM-CSF) gene-transduced tumor vaccine for patients with metastatic renal cell carcinoma (RCC) was initiated in 1998, as the first cancer gene therapy in Japan. The study is still on
Autor:
Martin G. Sanda, Shirley Clift, Glenn Dranoff, Drew M. Pardoll, Richard C. Mulligan, Elizabeth M. Jaffee, Sujatha R. Ayyagari, Jonathan W. Simons, Lawrence K. Cohen, Jonathan I. Epstein
Publikováno v:
The Journal of urology. 151(3)
The potential efficacy and clinical feasibility of gene therapy for prostate cancer were tested. Efficacy was tested using the Dunning rat prostate carcinoma model. Rats with anaplastic, hormone refractory prostate cancer treated with irradiated pros
Autor:
Ryo Kurita, Yukoh Nakazaki, Dale G. Ando, Shirley Clift, Fuyumi Takano, Kenzaburo Tani, Shigetaka Asano, Takao Hashiguchi
Publikováno v:
Blood. 104:5279-5279
Vaccination of GM-CSF-transduced tumor cells (GVAX®) has been demonstrated to induce cellular and humoral immune response to tumors in animal studies as well as human clinical trials. We have recently done clinical trials of GVAX® using autologous
Autor:
Kenzaburo Tani, Shigetaka Asano, Takao Hashiguchi, Dale G. Ando, Yukoh Nakazaki, Shirley Clift
Publikováno v:
Molecular Therapy. 9:S220
Vaccination of GM-CSF-transduced tumor cells (GVAX®) have been demonstrated to induce cellular and humoral immune response to tumors in animal studies as well as human clinical trials. We have recently done clinical trials of GVAX® using autologous