Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shirley Ben Joseph"'
Autor:
Ido Rippin, Netaly Khazanov, Shirley Ben Joseph, Tania Kudinov, Eva Berent, Sara Melisa Arciniegas Ruiz, Daniele Marciano, Laura Levy, Arie Gruzman, Hanoch Senderowitz, Hagit Eldar-Finkelman
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 22, p 8709 (2020)
The serine/threonine kinase, GSK-3, is a promising drug discovery target for treating multiple pathological disorders. Most GSK-3 inhibitors that were developed function as ATP competitive inhibitors, with typical limitations in specificity, safety a
Externí odkaz:
https://doaj.org/article/ff762e800dab45ae811f661ea1aa2c29
Autor:
Shirley Ben Joseph, Lilach Vaks, Amar Sarsor, Ido Rippin, Katherina Bonder, Hagit Eldar-Finkelman
Publikováno v:
Neurobiology of Disease, Vol 154, Iss, Pp 105336-(2021)
In Huntington's disease (HD), the mutant huntingtin (mHtt) accumulates as toxic aggregates in the striatum tissue, with deleterious effects on motor-coordination and cognitive functions. Reducing the levels of mHtt is therefore a promising therapeuti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82430bd6e6a6fc9dbff5516f0ea00373
https://pubmed.ncbi.nlm.nih.gov/33753290
https://pubmed.ncbi.nlm.nih.gov/33753290
Autor:
Hanoch Senderowitz, Ido Rippin, Laura Levy, Tania Kudinov, Sara Melisa Arciniegas Ruiz, Daniele Marciano, Shirley Ben Joseph, Netaly Khazanov, Eva Berent, Arie Gruzman, Hagit Eldar-Finkelman
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8709, p 8709 (2020)
Volume 21
Issue 22
International Journal of Molecular Sciences, Vol 21, Iss 8709, p 8709 (2020)
The serine/threonine kinase, GSK-3, is a promising drug discovery target for treating multiple pathological disorders. Most GSK-3 inhibitors that were developed function as ATP competitive inhibitors, with typical limitations in specificity, safety a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef57b445cdb274e3b6d433dad64dd8a
Autor:
Shannon M. Soucy, Anita Marchfelder, Mor Zarkor, Kim Eizenshtein, Israela Turgeman-Grott, Aris-Edda Stachler, Adit Naor, Sam Marton, Leah Reshef, Uri Gophna, Neta Altman-Price, Yarden Shalev, Shirley Ben Joseph
Publikováno v:
Nature microbiology
Nature Microbiology
Nature Microbiology
CRISPR–Cas systems provide prokaryotes with sequence-specific immunity against viruses and plasmids based on DNA acquired from these invaders, known as spacers. Surprisingly, many archaea possess spacers that match chromosomal genes of related spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414a510c2130d9258b2717405adc29bf
https://doi.org/10.1038/s41564-018-0302-8
https://doi.org/10.1038/s41564-018-0302-8
Autor:
Rippin I; Department of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Khazanov N; Department of Chemistry, Bar-Ilan University, Ramat Gan 5290002, Israel., Shirley Ben Joseph; Department of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Kudinov T; Department of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Berent E; Department of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Arciniegas Ruiz SM; Department of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel., Marciano D; Israel Institute for Biological Research, Ness Ziona 7410001, Israel., Levy L; Department of Chemistry, Bar-Ilan University, Ramat Gan 5290002, Israel., Gruzman A; Department of Chemistry, Bar-Ilan University, Ramat Gan 5290002, Israel., Senderowitz H; Department of Chemistry, Bar-Ilan University, Ramat Gan 5290002, Israel., Eldar-Finkelman H; Department of Human Molecular Genetics & Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 6997801, Israel.
Publikováno v:
International journal of molecular sciences [Int J Mol Sci] 2020 Nov 18; Vol. 21 (22). Date of Electronic Publication: 2020 Nov 18.