Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shirley A. Southern"'
Publikováno v:
British Journal of Cancer
We have demonstrated previously that high-risk human papillomaviruses (HPVs) induce tetrasomy in low-grade squamous intraepithelial lesions of the cervix. In this study we show that the E6 and E7 genes of high-risk HPV-16, but not those of low-risk H
Publikováno v:
Human Pathology. 32:1351-1355
In a recent study of low-grade cervical squamous intraepithelial lesions (SILs), we reported that infection with both low- and high-risk human papillomaviruses (HPVs) upregulated cyclin A, B, E, and Ki67 expression in basal and suprabasal cells. In v
Publikováno v:
British Journal of Cancer
Human papillomavirus (HPV) infection appears to be an early event in cervical carcinogenesis with additional abnormalities being required for biological transformation. We have analysed 179 low-grade cervical squamous intra-epithelial lesions (SILs)
Publikováno v:
International Journal of Cancer. 83:66-69
A polymorphism at codon 72 of the p53 gene, resulting in either an arginine or a proline residue in the protein, has been reported to affect the susceptibility of p53 to human papillomavirus (HPV) E6-mediated degradation in cultured cells. However, t
Publikováno v:
Human Pathology. 30:906-910
We have previously identified an inverse relationship between p53 and retinoblastoma protein (pRb) immunoreactivity in non-small cell carcinoma of the cervix. Because pRb is infrequently expressed in small cell carcinoma of the lung, we analyzed 25 s
Publikováno v:
International Journal of Cancer. 70:502-507
Human papillomavirus (HPV) infection has been widely implicated in cervical carcinogenesis, but it appears to be an early event, with other genetic abnormalities being required for biological transformation. In this study, interphase cytogenetic anal
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 80(4)
In this study, we demonstrate that expression of cyclin B protein is up-regulated and persists into the upper epithelial layers in parallel with cyclin A expression in high-grade squamous intraepithelial lesions (SIL) infected with human papillomavir
Publikováno v:
Diagnostic molecular pathology : the American journal of surgical pathology, part B. 7(2)
We have previously demonstrated that cross-hybridization between probe and target occurs in the analysis of human papillomavirus (HPV) 6 and 11, and HPV 16, 31 and 33 infection by in situ hybridization (ISH) in archival tissue biopsies. In this study