Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shirley A. Hanley"'
Autor:
Joana Cabral, Shirley A. Hanley, Jared Q. Gerlach, Neil O’Leary, Stephen Cunningham, Thomas Ritter, Rhodri Ceredig, Lokesh Joshi, Matthew D. Griffin
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Regulatory T-cells (Treg) are essential for maintaining immune homeostasis and tolerance. Surface glycosylation is ubiquitous on mammalian cells and regulates diverse biological processes. While it is currently well accepted that surface glycan expre
Externí odkaz:
https://doaj.org/article/af50a38afd7a440a8040dbc7099b4c0b
Autor:
Christine E. Schnitzler, Sofia N. Barreira, James M Gahan, Timothy Q. DuBuc, Uri Frank, Andreas D. Baxevanis, Eleni Chrysostomou, Paul Gonzalez, Shirley A. Hanley, Sebastian G. Gornik, Tara Buggie, Febrimarsa, Emma T. McMahon
Publikováno v:
Science
Conserved gene specifies germ cell Germ cells are the exclusive progenitors of gametes. In most studied animals, including humans, germ cells are produced only once during embryogenesis and are not replenished in adult life. DuBuc et al. studied germ
Autor:
Jared Q Gerlach, Anja Krüger, Susan Gallogly, Shirley A Hanley, Marie C Hogan, Christopher J Ward, Lokesh Joshi, Matthew D Griffin
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74801 (2013)
Urinary extracellular vesicles (uEVs) are released by cells throughout the nephron and contain biomolecules from their cells of origin. Although uEV-associated proteins and RNA have been studied in detail, little information exists regarding uEV glyc
Externí odkaz:
https://doaj.org/article/0124fd17aa1746c7a5c9b05a10927c96
Publikováno v:
Cytotherapy. 22:S84
Background & Aim Bone marrow-derived mesenchymal stromal cells (BM-MSCs) are an attractive candidate for use in regenerative therapies and are being widely investigated for the treatment of a broad spectrum of diseases. Despite this, the efficacy of
Autor:
Timothy O'Brien, Rhodri Ceredig, Eanna P. Connaughton, Shirley A. Hanley, Matthew D. Griffin, Stephanie M. Slevin, Noel F. Lowndes, Michael Conall Dennedy, Serika D. Naicker, John K. Eykelenboom
Publikováno v:
Immunology and Cell Biology
Human blood monocytes are subclassified as classical, intermediate and nonclassical. In this study, it was shown that conventionally defined human intermediate monocytes can be divided into two distinct subpopulations with mid- and high-level surface
Autor:
Rhodri Ceredig, Matthew D. Griffin, Shirley A. Hanley, Neil O'Leary, Jared Q. Gerlach, Thomas Ritter, Joana Cabral, Stephen Cunningham, Lokesh Joshi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Regulatory T-cells (T-reg) are essential for maintaining immune homeostasis and tolerance. Surface glycosylation is ubiquitous on mammalian cells and regulates diverse biological processes. While it is currently well accepted that surface glycan expr
Autor:
Robert A. Whiley, Xiaoju Shi, Stuart C. Fawell, Marie-Claire Faray-Kele, Shirley A. Hanley, Lucinda M. C. Hall, Michael A. Curtis, Joseph Aduse-Opoku
Publikováno v:
Infection and Immunity. 75:2071-2074
The rag locus of Porphyromonas gingivalis encodes a putative TonB-dependent outer membrane receptor, RagA, and a 55-kDa immunodominant antigen, RagB. Inactivation of either ragA or ragB prevented expression of both RagA and RagB. Both the ragA and ra
Publikováno v:
Stem Cell Research & Therapy
Introduction Conventionally cultured mouse bone marrow mesenchymal stromal cells (mBM-MSC) are a heterogeneous population that often initially contain contaminating haematopoietic cells. Variability in isolation methods, culture protocols and the lac
Autor:
Bairbre McNicholas, Howard O. Fearnhead, Michelle M. Duffy, David A. Monaghan, Matthew D. Griffin, Senthilkumar Alagesan, Jana Pindjakova, Shirley A. Hanley, Jill McMahon
Publikováno v:
American journal of physiology. Renal physiology. 307(12)
Mesenchymal stem cells (MSCs) suppress T helper (Th)17 cell differentiation and are being clinically pursued for conditions associated with aberrant Th17 responses. Whether such immunomodulatory effects are enhanced by coadministration of MSCs with o
Autor:
Alessia Stocca, Claas Baustian, Matthew D. Griffin, Rhodri Ceredig, Sonia Prado-López, Senthilkumar Alagesan, Shirley A. Hanley, Michelle M. Duffy
Publikováno v:
Immunology and cell biology. 92(7)
Multipotent mesenchymal stromal cells are multipotent cells capable of differentiating into different mesodermal cell types. Enigmatically, mesenchymal stromal cells present in the bone marrow support early lymphopoiesis yet can inhibit mature lympho