Zobrazeno 1 - 10
of 171
pro vyhledávání: '"Shirley, Luckhart"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Quantitative phase imaging (QPI) has become a vital tool in bioimaging, offering precise measurements of wavefront distortion and, thus, of key cellular metabolism metrics, such as dry mass and density. However, only a few QPI applications h
Externí odkaz:
https://doaj.org/article/35f3bdff09c542f881e9e55e800332d4
Autor:
Taylor A. Coles, Anna M. Briggs, Malayna G. Hambly, Nora Céspedes, Abigail M. Fellows, Hannah L. Kaylor, Alexandria D. Adams, Grace Van Susteren, Ronald E. Bentil, Michael A. Robert, Jeffrey A. Riffell, Edwin E. Lewis, Shirley Luckhart
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Blood levels of histamine and serotonin (5-HT) are altered in human malaria, and, at these levels, we have shown they have broad, independent effects on Anopheles stephensi following ingestion by this invasive mosquito. Given that histamine and 5-HT
Externí odkaz:
https://doaj.org/article/21a83eee51d844d2a39bd0ce779d544a
Autor:
Carolyne M. Kifude, Ashleigh Roberds, Janet Oyieko, Stephen Ocholla, Solomon Otieno, John N. Waitumbi, Jack Hutter, Hunter Smith, Nathanial K. Copeland, Shirley Luckhart, V. Ann Stewart
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Interactions between malaria and HIV-1 have important public health implications. Our previous cross-sectional studies showed significant associations between HIV-1 positivity and malarial parasitemia with an increased risk of gametocytemia. In this
Externí odkaz:
https://doaj.org/article/dee5820f319942d1950f169cb68fa38a
Autor:
Ashleigh Roberds, Carolyne Kifude, Janet Oyieko, Stephen Ocholla, James Mutunga, David Oullo, Charles Waga, Zhaozhang Li, Shirley Luckhart, V. Ann Stewart
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Despite significant developments towards malaria reduction, parasite transmission in the common context of HIV-1 co-infection and treatment for one or both infections has not been fully characterized. This is particularly important given that HIV-1 a
Externí odkaz:
https://doaj.org/article/bf71ba9d93054f74a4cbe12730166750
Autor:
Anna M. Briggs, Malayna G. Hambly, Raquel M. Simão-Gurge, Sarah M. Garrison, Zainab Khaku, Grace Van Susteren, Edwin E. Lewis, Jeffrey A. Riffell, Shirley Luckhart
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Approximately 3.4 billion people are at risk of malaria, a disease caused by infection with Plasmodium spp. parasites, which are transmitted by Anopheles mosquitoes. Individuals with severe falciparum malaria often exhibit changes in circulating bloo
Externí odkaz:
https://doaj.org/article/8d76778a29f244b595814af3226638c7
Autor:
Kimberly R. Andrews, Samuel S. Hunter, Brandi K. Torrevillas, Nora Céspedes, Sarah M. Garrison, Jessica Strickland, Delaney Wagers, Gretchen Hansten, Daniel D. New, Matthew W. Fagnan, Shirley Luckhart
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-12 (2021)
Abstract Background Speed congenics is an important tool for creating congenic mice to investigate gene functions, but current SNP genotyping methods for speed congenics are expensive. These methods usually rely on chip or array technologies, and a d
Externí odkaz:
https://doaj.org/article/f495c48afecc4d9c983ddd53e3f15cb4
Autor:
Chasity E Trammell, Gabriela Ramirez, Irma Sanchez-Vargas, Laura A St Clair, Oshani C Ratnayake, Shirley Luckhart, Rushika Perera, Alan G Goodman
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010411 (2022)
The recent global Zika epidemics have revealed the significant threat that mosquito-borne viruses pose. There are currently no effective vaccines or prophylactics to prevent Zika virus (ZIKV) infection. Limiting exposure to infected mosquitoes is the
Externí odkaz:
https://doaj.org/article/aeda74fc590d496b8e754a899cc1b9cc
Autor:
Nora Céspedes, Erinn L. Donnelly, Casey Lowder, Gretchen Hansten, Delaney Wagers, Anna M. Briggs, Joseph Schauer, Lori Haapanen, Magnus Åbrink, Judy Van de Water, Shirley Luckhart
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
An increase in mast cells (MCs) and MCs mediators has been observed in malaria-associated bacteremia, however, the role of these granulocytes in malarial immunity is poorly understood. Herein, we studied the role of mouse MC protease (Mcpt) 4, an ort
Externí odkaz:
https://doaj.org/article/985c41b206bb44cd853a4a634cd60748
Publikováno v:
Current Research in Microbial Sciences, Vol 2, Iss , Pp 100036- (2021)
Globally, malaria continues to be an enormous public health burden, with concomitant parasite-induced damage to the gastrointestinal (GI) barrier resulting in bacteremia-associated morbidity and mortality in both adults and children. Infected red blo
Externí odkaz:
https://doaj.org/article/ed97630db984447aa5dfb8b431b7633f
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Malaria/HIV-1 co-infection has become a significant public health problem in the tropics where there is geographical overlap of the two diseases. It is well described that co-infection impacts clinical progression of both diseases; however, less is k
Externí odkaz:
https://doaj.org/article/90830b64346f4fb3be0ed74d2fa4ee09