Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shirleen Soh"'
Publikováno v:
Viruses, Vol 13, Iss 7, p 1196 (2021)
Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying drug resistance mutations can guide the cli
Externí odkaz:
https://doaj.org/article/261e315c249942e9b7aaaeeaa1d0ef05
Publikováno v:
eLife, Vol 8 (2019)
Viruses like influenza are infamous for their ability to adapt to new hosts. Retrospective studies of natural zoonoses and passaging in the lab have identified a modest number of host-adaptive mutations. However, it is unclear if these mutations repr
Externí odkaz:
https://doaj.org/article/eeefa0aa9b104993becc20dc2cb8d6e5
Autor:
Y Q Shirleen Soh, Maria M Mikedis, Mina Kojima, Alexander K Godfrey, Dirk G de Rooij, David C Page
Publikováno v:
PLoS Genetics, Vol 13, Iss 4, p e1006704 (2017)
The meiosis-specific chromosomal events of homolog pairing, synapsis, and recombination occur over an extended meiotic prophase I that is many times longer than prophase of mitosis. Here we show that, in mice, maintenance of an extended meiotic proph
Externí odkaz:
https://doaj.org/article/d3d9eaae61064bb9bce366404b6f56be
Autor:
Y Q Shirleen Soh, Jan Philipp Junker, Mark E Gill, Jacob L Mueller, Alexander van Oudenaarden, David C Page
Publikováno v:
PLoS Genetics, Vol 11, Iss 9, p e1005531 (2015)
The chromosomal program of meiotic prophase, comprising events such as laying down of meiotic cohesins, synapsis between homologs, and homologous recombination, must be preceded and enabled by the regulated induction of meiotic prophase genes. This g
Externí odkaz:
https://doaj.org/article/8d5c0dc0df6e4619b022f3d266d114cd
Autor:
Yueh-Chiang Hu, Peter K Nicholls, Y Q Shirleen Soh, Joseph R Daniele, Jan Philipp Junker, Alexander van Oudenaarden, David C Page
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005019 (2015)
In mouse embryos at mid-gestation, primordial germ cells (PGCs) undergo licensing to become gametogenesis-competent cells (GCCs), gaining the capacity for meiotic initiation and sexual differentiation. GCCs then initiate either oogenesis or spermatog
Externí odkaz:
https://doaj.org/article/616a45d8b6c04c3ea2e837d2cad6cd0c
Publikováno v:
Viruses
Volume 13
Issue 7
Viruses, Vol 13, Iss 1196, p 1196 (2021)
Volume 13
Issue 7
Viruses, Vol 13, Iss 1196, p 1196 (2021)
Antivirals are used not only in the current treatment of influenza but are also stockpiled as a first line of defense against novel influenza strains for which vaccines have yet to be developed. Identifying drug resistance mutations can guide the cli
Autor:
Yong-An Lee, Chee Chong Lek, Amanpreet Kaur, Rong Gao, Agnes Bee Leng Ong, Yee Siang Lim, Shirleen Soh, Winston Chan, Yock Young Dan, Huck Hui Ng, Torsten Wuestefeld
Publikováno v:
Journal of Hepatology. 77:S694
Autor:
Jana Koubova, Yueh-Chiang Hu, Tanmoy Bhattacharyya, Y Q Shirleen Soh, Mark E Gill, Mary L Goodheart, Cathryn A Hogarth, Michael D Griswold, David C Page
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004541 (2014)
In all sexually reproducing organisms, cells of the germ line must transition from mitosis to meiosis. In mice, retinoic acid (RA), the extrinsic signal for meiotic initiation, activates transcription of Stra8, which is required for meiotic DNA repli
Externí odkaz:
https://doaj.org/article/08f3a1f3bfa04e63878513edce665a0c
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Viruses like influenza are infamous for their ability to adapt to new hosts. Retrospective studies of natural zoonoses and passaging in the lab have identified a modest number of host-adaptive mutations. However, it is unclear if these mutations repr