Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Shirisha Jonnalagadda"'
Autor:
Angelica V. Carmona, Shirisha Jonnalagadda, Alfie M. Case, Krishnaiah Maddeboina, Sravan K. Jonnalagadda, Louise F. Dow, Ling Duan, Trevor M. Penning, Paul C. Trippier
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Aldo-keto reductase 1C3 (AKR1C3) is a protein upregulated in prostate cancer, hematological malignancies, and other cancers where it contributes to proliferation and chemotherapeutic resistance. Androgen receptor splice variant 7 (ARv7) is t
Externí odkaz:
https://doaj.org/article/e4ce2a22fe6441639dc3ca4d9f796b99
Autor:
Chinnadurai Mani, Shirisha Jonnalagadda, Jojireddy Lingareddy, Sanjay Awasthi, William H. Gmeiner, Komaraiah Palle
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-14 (2019)
Abstract Background Breast cancer remains as one of the most lethal types of cancer in women. Among various subtypes, triple-negative breast cancer (TNBC) is the most aggressive and hard to treat type of breast cancer. Mechanistically, increased DNA
Externí odkaz:
https://doaj.org/article/63ccb4a51a8e47938273acfb56ab4b11
Autor:
Masoud Sadeghzadeh, Barbara Wenzel, Daniel Gündel, Winnie Deuther-Conrad, Magali Toussaint, Rareş-Petru Moldovan, Steffen Fischer, Friedrich-Alexander Ludwig, Rodrigo Teodoro, Shirisha Jonnalagadda, Sravan K. Jonnalagadda, Gerrit Schüürmann, Venkatram R. Mereddy, Lester R. Drewes, Peter Brust
Publikováno v:
Molecules, Vol 25, Iss 10, p 2309 (2020)
Monocarboxylate transporters 1-4 (MCT1-4) are involved in several metabolism-related diseases, especially cancer, providing the chance to be considered as relevant targets for diagnosis and therapy. [18F]FACH was recently developed and showed very pr
Externí odkaz:
https://doaj.org/article/0dea2432e8824c31a2e76d505164a53f
Autor:
Yong Zhang, Sejal Sharma, Shiva H. Esfahani, Shirisha Jonnalagadda, Aarfa Queen, Saeideh Nozohouri, Dhavalkumar Patel, Paul C. Trippier, Vardan T. Karamyan, Thomas J. Abbruscato
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Drug Discovery and Development.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0209a62d6175d80b022ee38c9291db58
https://doi.org/10.1124/jpet.122.533120
https://doi.org/10.1124/jpet.122.533120
Autor:
Sravan K. Jonnalagadda, Bader I. Huwaimel, Shirisha Jonnalagadda, Jered C. Garrison, Paul C. Trippier
Publikováno v:
J Org Chem
Synthesis of highly strained fused substituted dihydrobenzopyran cyclopropyl lactones derived from coumarin carboxylates are reported. Substrate scope tolerates a variety of 6- and 8-substituents on the coumarin ring. Substitution at the 5- or 7-posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75396225825283b133620ac115c17884
https://pubmed.ncbi.nlm.nih.gov/35258961
https://pubmed.ncbi.nlm.nih.gov/35258961
Autor:
Bader I. Huwaimel, Sravan K. Jonnalagadda, Shirisha Jonnalagadda, Shikha Kumari, Alessio Nocentini, Claudiu T. Supuran, Paul C. Trippier
Publikováno v:
Drug Development Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::291b6365befff40725158a254358c7b6
https://doi.org/10.1002/ddr.22049
https://doi.org/10.1002/ddr.22049
Autor:
Greeshma P. Kumpati, Michael J. Williams, Srinidhi Mereddy, Joseph L. Johnson, Shirisha Jonnalagadda
Publikováno v:
International Journal of Organic Chemistry. 12:53-63
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a22823c912c82a718e942855f0eeb791
https://doi.org/10.4236/ijoc.2022.122005
https://doi.org/10.4236/ijoc.2022.122005
Autor:
Bader Huwaimel, Sravan Jonnalagadda, Shirisha Jonnalagadda, Shikha Kumari, Alessio Nocentinic, Claudiu Supuran, Trippier Paul
Inhibition of specific carbonic anhydrase (CA) enzymes is a validated strategy for the development of agents to target cancer. The CA isoforms IX and XII are overexpressed in various human solid tumors wherein they play a critical role in regulating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c42b1c4495703dd386680082f9e387cf
https://doi.org/10.26434/chemrxiv-2023-7l7d0
https://doi.org/10.26434/chemrxiv-2023-7l7d0
Autor:
Chinnadurai Mani, Grady L. Nelson, Shirisha Jonnalagadda, Sravan K. Jonnalagadda, Conor T. Ronayne, Hithardha Palle, Lucas N. Solano, Jon M Holy, Jon N. Rumbley, Venkatram R. Mereddy
Publikováno v:
Biochemical and Biophysical Research Communications. 562:127-132
A novel nitrogen mustard CBISC has been synthesized and evaluated as an anticancer agent. CBISC has been shown to exhibit enhanced cell proliferation inhibition properties against mutant p53 cell lines colorectal cancer WiDr, pancreatic cancer (MIAPa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0582a924ef6da62c18ccdeb4776fa9a
https://doi.org/10.1016/j.bbrc.2021.05.062
https://doi.org/10.1016/j.bbrc.2021.05.062
Publikováno v:
Pathology and Oncology Research
The human papilloma virus (HPV) high-risk variants (HPV-HR) such as HPV16 and HPV18 are responsible for most HPV related cancers, including anogenital and head and neck cancers. Here, we present two patients with HPV-HR-associated gynecological malig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5dcd27e4b870a49741f6c7460075d36
http://europepmc.org/articles/PMC8720759
http://europepmc.org/articles/PMC8720759