Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Shirisha Amatya"'
Autor:
Christina Chaivorapol, Chamith Fonseka, Terry J. Fry, Shirisha Amatya, Zach Frye, Saurabh Paliwal, Jagesh V Shah, Samantha Davis, Patricia Cruite, Christopher Bandoro, Hina Iftikhar, Nikolas Balanis, Michael Laska, Lauren Pepper
Publikováno v:
Blood. 138:3983-3983
Introduction: The ability to deliver genes to specific cell types in vivo would have a profound therapeutic impact for a diverse set of diseases. For example, targeting T cells for in vivo delivery of a chimeric antigen receptor (CAR) to treat B cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3e0369233ad2f653cfce37fdbb546ce
https://doi.org/10.1182/blood-2021-149990
https://doi.org/10.1182/blood-2021-149990
Autor:
Heather Jewell, Akinola Olumide Emmanuel, Albert Ruzo, Boris Gorovits, Caspian Harding, Bindu Varghese, Yonatan Lipsitz, Vidur Patel, Justine Cunningham, Sundeep Chandra, Victoria Duback, Hemant Chavan, Joohwan Kim, Michelle Nguyen-McCarty, Shannon Joyce, Aaron E. Foster, Carmela Passaro, Sergey Lyubinetsky, Lauren Pepper, Jason Rodriguez, Trevor McGill, Kelan Hlavaty, Misha Shamashkin, Paige Baldwin, Terry J. Fry, Shirisha Amatya, Carl Co, Salvatore Iovino, Jagesh V Shah, Hanane Ennajdaoui, Jess Elman, Allyse Mazzarelli, Donna Dambach, Kutlu G. Elpek, Carrie Rocca, Vasily Vagin, James Kaczmarek, Pattie Cruite, Michael Laska
Publikováno v:
Blood. 138:2769-2769
Introduction: Ex vivo manufactured chimeric antigen receptor (CAR) T cell therapies are highly effective for treating B cell malignancies. However, the complexity, cost and time required to manufacture CAR T cells limits access. To overcome conventio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46946ed5099ec17431d5555f68d3aae8
https://doi.org/10.1182/blood-2021-148709
https://doi.org/10.1182/blood-2021-148709
Autor:
Sergey Lyubinetsky, Allyse Mazarelli, Jess Elman, Kutlu G. Elpek, Patty Cruite, Caspian Harding, Trevor McGill, Donna Dambach, Terry J. Fry, Salvatore Iovino, Carmela Passaro, Vidur Patel, Shirisha Amatya, Albert Ruzo, Kelan Hlavaty, Victoria Duback, Lauren Pepper, Anna Liang, Avani Parikh, Akinola Olumide Emmanuel, Jagesh V Shah, Samantha Crocker, Michael Laska, Jason Rodriguez, Hanane Ennajdaoui, Paige Baldwin
Publikováno v:
Cancer Research. 81:LB105-LB105
CAR T cells are highly effective at inducing remissions in patients with refractory B cell malignancies. The ex vivo process used to manufacture these therapies limits patient access and exposes T cells to non-physiologic conditions in culture. Viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9060fe6670dabb0084870caeaeacae6e
https://doi.org/10.1158/1538-7445.am2021-lb105
https://doi.org/10.1158/1538-7445.am2021-lb105