Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shirin Elhaik"'
Autor:
Hila Israelov, Orly Ravid, Dana Atrakchi, Daniel Rand, Shirin Elhaik, Yael Bresler, Rachel Twitto-Greenberg, Liora Omesi, Sigal Liraz-Zaltsman, Fabien Gosselet, Michal Schnaider Beeri, Itzik Cooper
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Abstract Background Excessive inflammation might activate and injure the blood-brain barrier (BBB), a common feature of many central nervous system (CNS) disorders. We previously developed an in vitro BBB injury model in which the organophosphate par
Externí odkaz:
https://doaj.org/article/0fb820df750949eeb24a86b3cdf76c1e
Autor:
Orly Ravid, Shirin Elhaik Goldman, David Macheto, Yael Bresler, Raquel Ines De Oliveira, Sigal Liraz-Zaltsman, Fabien Gosselet, Lucie Dehouck, Michal Schnaider Beeri, Itzik Cooper
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Organophosphorus compounds (OPs) are highly toxic chemicals widely used as pesticides (e.g., paraoxon (PX)- the active metabolite of the insecticide parathion) and as chemical warfare nerve agents. Blood-brain barrier (BBB) leakage has been shown in
Externí odkaz:
https://doaj.org/article/0340d799720b412390389fd8d5b637c5
Autor:
Shirin Elhaik Goldman, Itay Moshkovits, Avishai Shemesh, Ayelet Filiba, Yevgeny Tsirulsky, Elena Vronov, Marilou Shagan, Ron N Apte, D Aniel Benharroch, Danielle Karo-Atar, Ron Dagan, Ariel Munitz, Yaffa Mizrachi Nebenzahl, Angel Porgador
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160779 (2016)
The function of NCR1 was studied in a model of experimental asthma, classified as a type 1 hypersensitivity reaction, in mice. IgE levels were significantly increased in the serum of OVA immunized NCR1 deficient (NCR1gfp/gfp) mice in comparison to OV
Externí odkaz:
https://doaj.org/article/85d3c6e64b2c4cd1a39c19a88d679f26
Autor:
Shirin Elhaik-Goldman, Daniel Kafka, Rami Yossef, Uzi Hadad, Moshe Elkabets, Alexandra Vallon-Eberhard, Luai Hulihel, Steffen Jung, Hormas Ghadially, Alex Braiman, Ron N Apte, Ofer Mandelboim, Ron Dagan, Yaffa Mizrachi-Nebenzahl, Angel Porgador
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23472 (2011)
Natural killer (NK) cells serve as a crucial first line of defense against tumors, viral and bacterial infections. We studied the involvement of a principal activating natural killer cell receptor, natural cytotoxicity receptor 1 (NCR1), in the innat
Externí odkaz:
https://doaj.org/article/7d246dad28934f37a92a20806a227238
Autor:
Daniel Rand, Sigal Liraz-Zaltsman, Liora Omesi, Orly Ravid, Fabien Gosselet, Dana Atrakchi, Shirin Elhaik, Rachel Twitto-Greenberg, Michal Schnaider Beeri, Yael Bresler, Itzik Cooper, Hila Israelov
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation, BioMed Central, 2020, 17 (1), ⟨10.1186/s12974-020-01927-w⟩
Journal of Neuroinflammation
Journal of Neuroinflammation, BioMed Central, 2020, 17 (1), ⟨10.1186/s12974-020-01927-w⟩
Background Excessive inflammation might activate and injure the blood-brain barrier (BBB), a common feature of many central nervous system (CNS) disorders. We previously developed an in vitro BBB injury model in which the organophosphate paraoxon (PX
Autor:
Ariel Ohayon, Galia Feldman, Moshe Elkabets, Shahar Dotan, Yaffa Mizrachi Nebenzahl, Maxim Portnoi, Ditza Levin, Angel Porgador, Rosa Azhari, Eduard Ling, Itay Malka, Shirin Elhaik Goldman, Amir Talias, Edwin Swiatlo, Amit Lilo, Shalhevet Azriel, Ron Dagan, Daniel Kafka, Michael Tal, Ronald Ellis
Publikováno v:
International Journal of Molecular Medicine. 37:1127-1138
Streptococcus pneumoniae (S. pneumoniae) is a major pathogen worldwide. The currently available polysaccharide-based vaccines significantly reduce morbidity and mortality. However, the inherent disadvantages of the currently available polysaccharide-
Autor:
Itzik Cooper, David Last, David Guez, Shirley Sharabi, Shirin Elhaik Goldman, Irit Lubitz, Dianne Daniels, Sharona Salomon, Gregory Tamar, Tzur Tamir, Ronni Mardor, Mati Fridkin, Yoram Shechter, Yael Mardor
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 35:967-976
Despite aggressive therapy, existing treatments offer poor prognosis for glioblastoma multiforme patients, in part due to poor penetration of most drugs across the blood–brain barrier (BBB). We propose a minimal-invasive combined treatment approach
Akademický článek
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Akademický článek
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Autor:
Aviv Shish, Dana Atrakchi-Baranes, Sharone Naor, David Goez, Alicia Leikin-Frenkel, Shirin Elhaik Goldman, Michal Schnaider Beeri, Chen Shemesh, Yael Mardor, Rachel Twitto-Greenberg, Roni Lotan, Sigal Liraz Zaltsman, Shoval Tsach, Inbal Sharvit-Ginon, Itzik Cooper
Publikováno v:
Aging Cell
Type 2 diabetes (T2D) is associated with increased risk of Alzheimer's disease (AD). There is evidence for impaired blood–brain barrier (BBB) in both diseases, but its role in the interplay between them is not clear. Here, we investigated the effec