Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shiri Shahmoon"'
Autor:
Ido Wolf, Shiri Shahmoon, Michal Ben Ami, Yael Levy-Shraga, Kineret Mazor-Aronovitch, Orit Pinhas-Hamiel, Yonatan Yeshayahu, Rina Hemi, Hannah Kanety, Tami Rubinek, Dalit Modan-Moses
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107174 (2014)
Klotho is an aging-modulating protein expressed mainly in the kidneys and choroid plexus, which can also be shed, released into the circulation and act as a hormone. Klotho deficient mice are smaller compared to their wild-type counterparts and their
Externí odkaz:
https://doaj.org/article/fadcd7d0c514418c87d4bce1dd47e6a7
Autor:
Ido Wolf, Sarit Aviel-Ronen, Shiri Shahmoon, Rotem Sertchook, Adva Yeheskel, Keren Merenbakh-Lamin, Tami Rubinek, Hagai Ligumsky
Secretion analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::732386dc7847ea4c4a075db5da0a11de
https://doi.org/10.1158/1541-7786.22514886
https://doi.org/10.1158/1541-7786.22514886
Autor:
Raun D. Melmed, Robert L. Findling, Carmen M. Schröder, Paul Gringras, Shiri Shahmoon, Nava Zisapel, Athanasios Maras, John Breddy, Beth A. Malow, Tali Nir
Publikováno v:
Journal of Autism and Developmental Disorders
A randomized, 13-weeks, placebo-controlled double-blind study in 125 subjects aged 2–17.5 years with Autism Spectrum Disorder or Smith-Magenis syndrome and insomnia demonstrated efficacy and safety of easily-swallowed prolonged-release melatonin mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1269cc099804d9a5361b333e96d8e8eb
https://doi.org/10.1007/s10803-019-04046-5
https://doi.org/10.1007/s10803-019-04046-5
Autor:
Shiri Shahmoon, Tali Nir, Nava Zisapel, Carmen M. Schröder, John Breddy, Robert L. Findling, Athanasios Maras, Beth A. Malow, Paul Gringras
Publikováno v:
Journal of Child and Adolescent Psychopharmacology
Objective: A recent double-blind randomized placebo-controlled study demonstrated 3-month efficacy and safety of a novel pediatric-appropriate prolonged-release melatonin (PedPRM) for insomnia in children and adolescents with autism spectrum disorder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dadf4228100c066e11f03984da85ee
https://doi.org/10.1089/cap.2018.0020
https://doi.org/10.1089/cap.2018.0020
Autor:
Tami Rubinek, Shiri Shahmoon, Rina Hemi, Ido Wolf, Yael Levy-Shraga, Hannah Kanety, Yonatan Yeshayahu, Ram Doolman, Dalit Modan-Moses, Ayelet Shabtay-Orbach, Kineret Mazor-Aronovitch, Michal Ben Ami
Publikováno v:
Metabolism. 65:1597-1604
Klotho is an aging-modulating protein expressed mainly in the kidneys, which can be cleaved and shed to act as a circulating hormone. Several lines of evidence suggest a tight interaction between klotho and the GH-IGF-I axis. We showed previously tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34aa6856f3a5d468d6554c3933dd747
https://doi.org/10.1016/j.metabol.2016.08.004
https://doi.org/10.1016/j.metabol.2016.08.004
Autor:
Tammi Rubinstein, Chen Varol, Gilad W. Vainer, Ehud Zigmond, Gil Har-Zahav, Tal Etan, Nir Skalka, Iris Barshack, Rina Rosin-Arbesfeld, Keren Merenbakh-Lamin, Shiri Shahmoon, Metsada Pasmanik-Chor, Tami Rubinek, Ido Wolf
Publikováno v:
Oncogene. 38(6)
Klotho is an anti-aging transmembrane protein, which can be shed and function as a hormone. Accumulating data indicate klotho as a tumor suppressor in a wide array of malignancies and indicate the subdomain KL1 as the active region of the protein. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62525922d5194febd82f5b27a8f28088
https://pubmed.ncbi.nlm.nih.gov/30232408
https://pubmed.ncbi.nlm.nih.gov/30232408
Autor:
Tami Rubinek, Sarit Aviel-Ronen, Rotem Sertchook, Adva Yeheskel, Hagai Ligumsky, Ido Wolf, Keren Merenbakh-Lamin, Shiri Shahmoon
Publikováno v:
Molecular cancer research : MCR. 13(10)
Klotho is a transmembrane protein containing two internal repeats, KL1 and KL2, both displaying significant homology to members of the β-glycosidase family. Klotho is expressed in the kidney, brain, and various endocrine tissues, but can also be cle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3580badf8bf1a507bcc3552cd1fa751b
https://pubmed.ncbi.nlm.nih.gov/26113466
https://pubmed.ncbi.nlm.nih.gov/26113466
Autor:
Chen Varol, Tal Etan, Tammi Rubinstein, Tami Rubinek, Ido Wolf, Shiri Shahmoon, Rina Rosin-Arbesfeld, Iris Barshack, Ehud Zigmond
Publikováno v:
Cancer Research. 77:4507-4507
Klotho is a transmembrane protein, which can be shed and act as a circulating hormone. Klotho-deficient mice manifest a syndrome resembling accelerated aging, while klotho overexpression extends life span. We previously identified klotho as a breast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::948cf02e0001645fa3a46074da4d8c18
https://doi.org/10.1158/1538-7445.am2017-4507
https://doi.org/10.1158/1538-7445.am2017-4507
Autor:
Shimrit Ilana Ziv, Hannah Kanety, Ido Wolf, Rina Hemi, Daniel Stein, Dalit Modan-Moses, Shiri Shahmoon, Tami Rubinek
Publikováno v:
Clinical nutrition (Edinburgh, Scotland). 35(4)
Summary Background & aims Klotho is a trans-membrane protein which can be shed to act as a hormone; its blood levels may be regulated by the GH/IGF-1 axis. Klotho deficient mice exhibit short lifespan and characteristics of aging and malnutrition, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad60d86080d79fe08c8d33a19b6bcdc
https://pubmed.ncbi.nlm.nih.gov/26243062
https://pubmed.ncbi.nlm.nih.gov/26243062
Autor:
Tami Rubinek, Ilan Shimon, Shiri Shahmoon, Zvi R. Cohen, Moshe Hadani, Hadara Rubinfeld, Ido Wolf
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 307(3)
Klotho is a transmembranal protein highly expressed in the kidneys, choroid plexus, and anterior pituitary. Klotho can also be cleaved and shed and acts as a circulating hormone. Klotho-deficient mice ( kl/kl mice) develop a phenotype resembling earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cd719a81f0783c3020da6ca7f511df5
https://pubmed.ncbi.nlm.nih.gov/24939736
https://pubmed.ncbi.nlm.nih.gov/24939736