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pro vyhledávání: '"Shireen Shiraz Khayat"'
Autor:
Megan M Dacek, Keifer Kurtz, Patrick Wallisch, Stephanie A Pierre, Shireen Shiraz Khayat, Christopher M Bourne, Thomas J Gardner, Kristen C Vogt, Nica Aquino, Anas Younes, David A Scheinberg
Publikováno v:
Blood.
Chimeric antigen receptor (CAR) T cell therapy has shown success in the treatment of hematopoietic malignancies; however, relapse remains a significant issue. To overcome this, we engineered "Orexi" CAR T cells to locally secrete a high affinity CD47