Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shireen Kahai"'
Autor:
Shireen Kahai, Shao-Chen Lee, Daniel Y Lee, Jennifer Yang, Minhui Li, Chia-Hui Wang, Zide Jiang, Yaou Zhang, Chun Peng, Burton B Yang
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7535 (2009)
MicroRNAs (miRNAs) are small fragments of single-stranded RNA containing 18-24 nucleotides, and are generated from endogenous transcripts. MicroRNAs function in post-transcriptional gene silencing by targeting the 3'-untranslated region (UTR) of mRNA
Externí odkaz:
https://doaj.org/article/64fe0f206d8d4b82b9f685e58aee0ba8
Autor:
Chia-Hui Wang, Daniel Y Lee, Zhaoqun Deng, Zina Jeyapalan, Shao-Chen Lee, Shireen Kahai, Wei-Yang Lu, Yaou Zhang, Burton B Yang
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2420 (2008)
Morphogenesis is crucial to initiate physiological development and tumor invasion. Here we show that a microRNA controls zonation morphogenesis by targeting hyaluronan receptor CD44. We have developed a novel system to study microRNA functions by gen
Externí odkaz:
https://doaj.org/article/00c96f8598424fb48c6aa9919d29b5ec
Autor:
Peng-Sheng Zheng, Burton B. Yang, Chung-Kwun Amy Wong, Jianping Wen, Marciano Reis, Daniel Y. Lee, Cathy Sparling, Zhaoqun Deng, David P. La Pierre, Shireen Kahai
Publikováno v:
Journal of Biological Chemistry. 281:8175-8182
We have detected versican, a member of the large chondroitin sulfate proteoglycans, and its degraded C-terminal G3 fragments in human plasma and observed that the versican G3 domain promoted blood coagulation. Silencing G3 expression with small inter
Publikováno v:
Matrix Biology. 23:445-455
Bone matrix contains high concentrations of growth factors that are known to play important regulatory roles during osteogenesis, particularly transforming growth factor-beta (TGF-beta). Divergent effects of TGF-beta on bone formation have been repor
Publikováno v:
FEBS letters. 584(1)
We found that nephronectin was significantly down-regulated by TGF-β1. To determine the function of nephronectin in osteogenesis, we generated various constructs to produce stable MC3T3-E1 cell lines, expressing and secreting nephronectin protein, i
Autor:
Chia Hui Wang, Yaou Zhang, Shireen Kahai, Daniel Y. Lee, Chun Peng, Minhui Li, Jennifer Yang, Burton B. Yang, Shao-Chen Lee, Zide Jiang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 10, p e7535 (2009)
PLoS ONE, Vol 4, Iss 10, p e7535 (2009)
MicroRNAs (miRNAs) are small fragments of single-stranded RNA containing 18-24 nucleotides, and are generated from endogenous transcripts. MicroRNAs function in post-transcriptional gene silencing by targeting the 3′-untranslated region (UTR) of mR
Autor:
Shao-Chen Lee, Chia-Hui Wang, Zhaoqun Deng, Burton B. Yang, Daniel Y. Lee, Zina Jeyapalan, Shireen Kahai, Yaou Zhang, Wei-Yang Lu
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 6, p e2420 (2008)
PLoS ONE, Vol 3, Iss 6, p e2420 (2008)
Morphogenesis is crucial to initiate physiological development and tumor invasion. Here we show that a microRNA controls zonation morphogenesis by targeting hyaluronan receptor CD44. We have developed a novel system to study microRNA functions by gen
Publikováno v:
Matrix Biology. 25:S76-S77
Publikováno v:
FEBS Letters. (13):2877-2882
We used cDNA microarray to identify transforming growth factor beta (TGF-beta) responsive target genes during osteoblast development and found that nephronectin (Npnt) is one such gene that is significantly down-regulated. Here we report the role of