Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shireby, Gemma L"'
Autor:
Steg, Leonard C.1 (AUTHOR), Shireby, Gemma L.1 (AUTHOR), Imm, Jennifer1 (AUTHOR), Davies, Jonathan P.1 (AUTHOR), Franklin, Alice1 (AUTHOR), Flynn, Robert1 (AUTHOR), Namboori, Seema C.1 (AUTHOR), Bhinge, Akshay1 (AUTHOR), Jeffries, Aaron R.1 (AUTHOR), Burrage, Joe1 (AUTHOR), Neilson, Grant W. A.1 (AUTHOR), Walker, Emma M.1 (AUTHOR), Perfect, Leo W.2 (AUTHOR), Price, Jack2 (AUTHOR), McAlonan, Grainne3,4,5 (AUTHOR), Srivastava, Deepak P.2,4 (AUTHOR), Bray, Nicholas J.6 (AUTHOR), Cope, Emma L.7 (AUTHOR), Jones, Kimberley M.7 (AUTHOR), Allen, Nicholas D.7 (AUTHOR)
Publikováno v:
Molecular Brain. 6/26/2021, Vol. 14 Issue 1, p1-11. 11p.
Autor:
Hop, Paul J., Zwamborn, Ramona A. J., Hannon, Eilis, Shireby, Gemma L., Nabais, Marta F., Walker, Emma M., van Rheenen, Wouter, van Vugt, Joke J. F. A., Dekker, Annelot M., Westeneng, Henk-Jan, Tazelaar, Gijs H. P., Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Bert A., Isaacs, Aaron, Uitterlinden, Andre G., van Eijk, Kristel R., van Meurs, Joyce, Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, Moisse, Matthieu, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha V., Jansen, Rick, van ‘t Hof, Peter, Deelen, Patrick, Nooren, Irene, t Hoen, Peter A. C., Heijmans, Bastiaan T., Moed, Matthijs, Baird, Denis, Franke, Lude, Vermaat, Martijn, Luijk, Rene, Jan Bonder, Marc, van Dijk, Freerk, Arindrarto, Wibowo, Al Khleifat, Ahmad, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik W., Al-Chalabi, Ammar, Wray, Naomi R., Bensimon, Gilbert, Hardiman, Orla, Iacoangeli, Alfredo, Chio, Adriano, Smith, George Davey, Mill, Jonathan, Ticozzi, Nicola, Ratti, Antonia, Cooper-Knock, Jonathan, Morrison, Karen E., Shaw, Pamela J., Basak, A. Nazli, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Brunetti, Maura, Grassano, Maurizio, Gotkine, Marc, Lerner, Yossef, Zabari, Michal, Vourc’h, Patrick, Corcia, Philippe, Couratier, Philippe, Mora Pardina, Jesus S., Salas, Teresa, Dion, Patrick, Ross, Jay P., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Nicholson, Garth, Rowe, Dominic B., Pamphlett, Roger, Mather, Karen A., Sachdev, Perminder S., Furlong, Sarah, Garton, Fleur C., Henders, Anjali K., Lin, Tian, Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Williams, Kelly L., Neto, Miguel Mitne, Cauchi, Ruben J., Blair, Ian P., Kiernan, Matthew C., Drory, Vivian, Povedano, Monica, Carvalho, Mamede, Pinto, Susana, Weber, Markus, Rouleau, Guy A., Silani, Vincenzo, Landers, John E., Shaw, Christopher E., Andersen, Peter M., McRae, Allan F., van Es, Michael A., Pasterkamp, R. Jeroen, McLaughlin, Russell L., Kenna, Kevin P., Tsai, Ellen, Runz, Heiko, Van Damme, Philip, Boomsma, Dorret I., Pool, Rene, van Dongen, Jenny, Hottenga, Joukje J., van Greevenbroek, Marleen M. J., Stehouwer, Coen D.A., van der Kallen, Carla J.H., Schalkwijk, Casper G., Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje F.
Publikováno v:
Science Translational Medicine, 14(633):eabj0264. AMER ASSOC ADVANCEMENT SCIENCE
Science Translational Medicine, 14(633):eabj0264. American Association for the Advancement of Science
Hop, P J, Zwamborn, R A J, Hannon, E, Shireby, G L, Nabais, M F, Walker, E M, van Rheenen, W, van Vugt, J J F A, Dekker, A M, Westeneng, H J, Tazelaar, G H P, van Eijk, K R, Moisse, M, Baird, D, Al Khleifat, A, Iacoangeli, A, Ticozzi, N, Ratti, A, Cooper-Knock, J, Morrison, K E, Shaw, P J, Basak, A N, Chiò, A, Calvo, A, Moglia, C, Canosa, A, Brunetti, M, Grassano, M, Gotkine, M, Lerner, Y, Zabari, M, Vourc'H, P, Corcia, P, Couratier, P, Mora Pardina, J S, Salas, T, Dion, P, Ross, J P, Henderson, R D, Mathers, S, McCombe, P A, Needham, M, Nicholson, G, Rowe, D B, Pamphlett, R, Mather, K A, Sachdev, P S & Furlong, S & Shaw, C E & Al-Chalabi, A 2022, ' Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS ', Science Translational Medicine, vol. 14, no. 633, eabj0264 . https://doi.org/10.1126/scitranslmed.abj0264
Science Translational Medicine, 14633
BIOS Consortium 2022, ' Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS ', Science Translational Medicine, vol. 14, no. 633, eabj0264, pp. eabj0264 . https://doi.org/10.1126/scitranslmed.abj0264
Sci Transl Med
Science Translational Medicine, 14(633):eabj0264. American Association for the Advancement of Science
Hop, P J, Zwamborn, R A J, Hannon, E, Shireby, G L, Nabais, M F, Walker, E M, van Rheenen, W, van Vugt, J J F A, Dekker, A M, Westeneng, H J, Tazelaar, G H P, van Eijk, K R, Moisse, M, Baird, D, Al Khleifat, A, Iacoangeli, A, Ticozzi, N, Ratti, A, Cooper-Knock, J, Morrison, K E, Shaw, P J, Basak, A N, Chiò, A, Calvo, A, Moglia, C, Canosa, A, Brunetti, M, Grassano, M, Gotkine, M, Lerner, Y, Zabari, M, Vourc'H, P, Corcia, P, Couratier, P, Mora Pardina, J S, Salas, T, Dion, P, Ross, J P, Henderson, R D, Mathers, S, McCombe, P A, Needham, M, Nicholson, G, Rowe, D B, Pamphlett, R, Mather, K A, Sachdev, P S & Furlong, S & Shaw, C E & Al-Chalabi, A 2022, ' Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS ', Science Translational Medicine, vol. 14, no. 633, eabj0264 . https://doi.org/10.1126/scitranslmed.abj0264
Science Translational Medicine, 14633
BIOS Consortium 2022, ' Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS ', Science Translational Medicine, vol. 14, no. 633, eabj0264, pp. eabj0264 . https://doi.org/10.1126/scitranslmed.abj0264
Sci Transl Med
Copyright © 2022 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease wit
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease wit
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, Hannon, Eilis
Additional file 3: Fig. S1. Histogram of age distribution. Chronological age of the fetal samples measured in days post-conception in A) training data, B) testing data and C) validation data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d9f9281e77f40fa6ae738248193572
Autor:
Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, Hannon, Eilis
Additional file 1: Table S1. Summary of fetal, adult and cellular datasets.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31cc2111bb5bb9b00c409ab473e8ce8e
Autor:
Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, Hannon, Eilis
Additional file 2: Table S2. Intercept and coefficients of the Fetal Brain Clock.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09593d6cd56f538159ad622c8ba35951
Autor:
Steg, Leonard C., Shireby, Gemma L., Imm, Jennifer, Davies, Jonathan P., Franklin, Alice, Flynn, Robert, Namboori, Seema C., Bhinge, Akshay, Jeffries, Aaron R., Burrage, Joe, Neilson, Grant W. A., Walker, Emma M., Perfect, Leo W., Price, Jack, McAlonan, Grainne, Srivastava, Deepak P., Bray, Nicholas J., Cope, Emma L., Jones, Kimberley M., Allen, Nicholas D., Pishva, Ehsan, Dempster, Emma L., Lunnon, Katie, Mill, Jonathan, Hannon, Eilis
Additional file 4: Fig. S2. Comparison of predictions from the four DNAm clocks in the training data (n = 193). Shown are scatterplots comparing chronological age (x-axis; days post-conception) against predicted epigenetic age (y-axis; days post-conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4adca98a6667bb029bfd225bbd6909e1
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Hannon E; College of Medicine and Health, University of Exeter, Exeter, Devon, EX2 5DW, UK., Shireby GL; College of Medicine and Health, University of Exeter, Exeter, Devon, EX2 5DW, UK., Brookes K; School of Science & Technology, Nottingham Trent University, Nottingham, NG11 8NF, UK., Attems J; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK., Sims R; Division of Psychological Medicine and Clinical Neurosciences, School of Medicine, Cardiff University, Cardiff, CF24 4HQ, UK., Cairns NJ; College of Medicine and Health, University of Exeter, Exeter, Devon, EX2 5DW, UK., Love S; Bristol Medical School (THS), University of Bristol, Bristol, BS2 8DZ, UK., Thomas AJ; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE1 7RU, UK., Morgan K; Human Genetics Group, School of Life Sciences, University of Nottingham, Nottingham, NG7 2RD, UK., Francis PT; College of Medicine and Health, University of Exeter, Exeter, Devon, EX2 5DW, UK., Mill J; College of Medicine and Health, University of Exeter, Exeter, Devon, EX2 5DW, UK.
Publikováno v:
Brain communications [Brain Commun] 2020 Oct 12; Vol. 2 (2), pp. fcaa167. Date of Electronic Publication: 2020 Oct 12 (Print Publication: 2020).