Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shirdi E. Schmiel"'
Autor:
Christine Robinson, Carly Baehr, Shirdi E. Schmiel, Claudia Accetturo, Daniel L. Mueller, Marco Pravetoni
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 15, Iss 4, Pp 909-917 (2019)
Opioid use disorders (OUD) and fatal overdoses are a national emergency in the United States. Therapeutic vaccines offer a promising strategy to treat OUD and reduce the incidence of overdose. Immunization with opioid-based haptens conjugated to immu
Externí odkaz:
https://doaj.org/article/1b30b28fd85c4879a92a06ee87143378
Autor:
Londyn J. Robinson, Shirdi E. Schmiel, Na Zhang, Thomas W. Blankespoor, Lokesh A. Kalekar, Daniel L. Mueller
Publikováno v:
Arthritis & Rheumatology. 71:773-783
Objective CD4 germinal center (GC)-follicular helper T (Tfh) cells are important in the pathogenesis of autoimmune arthritis. Previous studies have shown that adenosine 2a receptor (A2aR; Adora2a) signaling can divert CD4 T cells away from the GC-Tfh
Autor:
Marco Pravetoni, Daniel L. Mueller, Shirdi E. Schmiel, Carly Baehr, Claudia Accetturo, Christine Robinson
Publikováno v:
Human vaccinesimmunotherapeutics. 15(4)
Opioid use disorders (OUD) and fatal overdoses are a national emergency in the United States. Therapeutic vaccines offer a promising strategy to treat OUD and reduce the incidence of overdose. Immunization with opioid-based haptens conjugated to immu
Autor:
Sarada L. Nandiwada, Deepali Malhotra, M. Gerard O'Sullivan, Marc K. Jenkins, Shirdi E. Schmiel, Lokesh A. Kalekar, Daniel L. Mueller, Kristin A. Hogquist, Gretta L. Stritesky, Laura O. Barsness, Brian T. Fife, Na Zhang, Wing Y Lam, Kristen E. Pauken, Jonathan L. Linehan
Publikováno v:
Nature immunology
The role of anergy, an acquired state of T cell functional unresponsiveness, in natural peripheral tolerance remains unclear. In this study, we found that anergy was selectively induced in fetal antigen-specific maternal CD4(+) T cells during pregnan
Publikováno v:
The Journal of Immunology. 202:50.5-50.5
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) encodes a lymphoid tyrosine phosphatase adaptor molecule involved in many biological pathways. Studies have shown an association with the minor allelic variant of PTPN22, R620W, and increased
Publikováno v:
The Journal of Immunology. 189:2537-2544
Recent studies have shed light on the connection between elevated erythropoetin production/spleen erythropoiesis and increased susceptibility to Salmonella infection. In this article, we provide another mouse model, the SIRPα-deficient (Sirpα−/
Publikováno v:
The Journal of Immunology. 200:100.2-100.2
Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) encodes lymphoid tyrosine phosphatase (Lyp) adaptor molecule that is involved in numerous biochemical pathways in hematopoietic cells. Studies have shown an association with the minor allelic
Publikováno v:
The Journal of Immunology. 200:181.20-181.20
Heroin and prescription opioid abuse and overdose have been declared a national emergency in the United States. Compared to current medications, vaccines provide a complementary long-lasting, safe and cost-effective therapeutic strategy. Since the ef
Publikováno v:
The Journal of Immunology. 196:210.5-210.5
Enhanced production of high affinity class-switched autoantibodies contributes to pathological symptoms of autoimmune diseases. Full penetrance of autoantibody production appears to rely on help from germinal center follicular helper T cells (GC TFH