Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Shiran Lv"'
Autor:
Youqi Tao, Yunpeng Sun, Shiran Lv, Wencheng Xia, Kun Zhao, Qianhui Xu, Qinyue Zhao, Lin He, Weidong Le, Yong Wang, Cong Liu, Dan Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
The Cryo-EM structures reported in this work reveal how heparin incorporates into α-syn fibril formation to determine fibril polymorphs. This highlights the role of biological polymers in the conformational selection and neuropathological regulation
Externí odkaz:
https://doaj.org/article/124bce3298094585a4da044fd086b517
Autor:
Houfang Long, Kaiwen He, Cong Liu, Wencheng Xia, Shiran Lv, Yang Liu, Yunpeng Sun, Zhengtao Liu, Weitong Zheng, Zhenying Liu, Kun Zhao, Dan Li
Publikováno v:
Proc Natl Acad Sci U S A
Heterozygous point mutations of α-synuclein (α-syn) have been linked to the early onset and rapid progression of familial Parkinson's diseases (fPD). However, the interplay between hereditary mutant and wild-type (WT) α-syn and its role in the exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93aa20d21c102dc8279a3929701b95d8
https://doi.org/10.1073/pnas.2012435118
https://doi.org/10.1073/pnas.2012435118