Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shira Sagie"'
Publikováno v:
PLoS ONE, Vol 18, Iss 9, p e0281561 (2023)
BackgroundCancer death rates are declining, in part due to smoking cessation, better detection and new treatments; nevertheless, a large fraction of metastatic cancer patients die soon after diagnosis. Few studies and interventions focus on these pat
Externí odkaz:
https://doaj.org/article/4d35cdac674a4e92a3fd736ae6224eed
Publikováno v:
International Journal for Equity in Health, Vol 20, Iss 1, Pp 1-10 (2021)
Abstract Background Inequalities in healthcare utilization exist across ethnic groups; however, the contributions of health-related knowledge and psychosocial factors to these inequalities remain unclear. We examined associations of social determinan
Externí odkaz:
https://doaj.org/article/9c49a8035afb4a30b31e43424aade366
Autor:
Shira Sagie, Shir Toubiana, Stella R. Hartono, Hagar Katzir, Aya Tzur-Gilat, Shany Havazelet, Claire Francastel, Guillaume Velasco, Frédéric Chédin, Sara Selig
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
ICF syndrome cells exhibit shortened telomeres and elevated levels of the noncoding RNA TERRA. Here the authors show this is associated with high levels of DNA damage, suggesting an increase in telomere dysfunction due to the formation of DNA: RNA hy
Externí odkaz:
https://doaj.org/article/a6ea7685f09c4013935240ad88a3e9f7
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215639 (2019)
BackgroundDisparities in non-communicable diseases (NCDs) may affect health care utilization. We compared the correlates of hospitalizations in internal medicine divisions, of adults with NCDs, between the main population groups in Israel.MethodsA cr
Externí odkaz:
https://doaj.org/article/05cc0e38418b41978752413283e2b11b
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 172
Despite major progress over the past decade in the field of lung cancer care, only mild advances have occurred in Small Cell Lung Cancer (SCLC), with prognosis remaining poor. Based on two randomized clinical trials (RCTs), two checkpoint-inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb9752871ab1ae26253d39ce3a81bd6
https://pubmed.ncbi.nlm.nih.gov/36087486
https://pubmed.ncbi.nlm.nih.gov/36087486
Autor:
Shir Toubiana, Omer Edni, Shira Sagie, Nirit Katzin, Joseph Weinberg, Tal Kozlovski, Tzviel Frostig, Irit Bar-Am, Sara Selig
Publikováno v:
Human Molecular Genetics. 26:4244-4256
Mutations in the de novo DNA methyltransferase DNMT3B lead to Immunodeficiency, Centromeric Instability and Facial anomalies (ICF) syndrome, type I. This syndrome is characterized, among other hypomethylated genomic loci, by severe subtelomeric hypom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b3187e3feb1d2a172f4ef582197c0a7
https://doi.org/10.1093/hmg/ddx313
https://doi.org/10.1093/hmg/ddx313
Autor:
Snezana Maljevic, Shira Sagie, Seo-Kyung Chung, Mark I. Rees, Dorit Lev, Keren Yosovich, Katja Detert, Tally Lerman-Sagie, Holger Lerche
Publikováno v:
Brain : a journal of neurology. 141(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d846963c41dd458b6995d5acc8652d3d
https://pubmed.ncbi.nlm.nih.gov/29846532
https://pubmed.ncbi.nlm.nih.gov/29846532
Autor:
Claire Francastel, Stella R. Hartono, Shany Havazelet, Guillaume Velasco, Shir Toubiana, Aya Tzur-Gilat, Sara Selig, Shira Sagie, Frédéric Chédin, Hagar Katzir
Publikováno v:
Nature Communications
Nature communications, vol 8, iss 1
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature communications, vol 8, iss 1
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
DNA:RNA hybrids, nucleic acid structures with diverse physiological functions, can disrupt genome integrity when dysregulated. Human telomeres were shown to form hybrids with the lncRNA TERRA, yet the formation and distribution of these hybrids among
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d2e6909dad8d62a2f523f245b4fbdd7
https://pubmed.ncbi.nlm.nih.gov/28117327
https://pubmed.ncbi.nlm.nih.gov/28117327
Autor:
Elena Ribakovsky, Keren Cesarkas, Elon Pras, Avishay Lahad, Atar Lev, Michalle Soudack, Noa Greenberg-Kushnir, Shulamit Katz, Iris Barshack, Yehuda Tzfati, Wadi Hazou, Galina Glousker, Batia Weiss, Michele Rhodes, Ninette Amariglio, Haifa A. Aqeilan, Ortal Barel, Gideon Rechavi, David L. Wiest, Amos J. Simon, Eran Eyal, Yong Zhang, Nitzan Kol, Anna Rylova, Hagar Katzir, Sara Selig, Raz Somech, Carlos Simon, Hana Poran, Shira Sagie, Haike Reznik-Wolf, Ginette Schiby, Yechezkel Sidi
Publikováno v:
The Journal of Experimental Medicine
Somech and colleagues identify two new mutations in STN1 that causes Coats plus syndrome and telomere abnormalities in human, recapitulated in a zebra fish model.
The analysis of individuals with telomere defects may shed light on the delicate i
The analysis of individuals with telomere defects may shed light on the delicate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab55f1b386f66be4d71d33e61fa246a
https://pubmed.ncbi.nlm.nih.gov/27432940
https://pubmed.ncbi.nlm.nih.gov/27432940
Autor:
Rony Shaked, Dan Geiger, Maty Tzukerman, Alaa Ghanayim, Shiran Yehezkel, Erika Ellran, Hagar Katzir, Sara Selig, Shira Sagie, Ilana Laevsky
Publikováno v:
Human molecular genetics. 23(14)
Human telomeric regions are packaged as constitutive heterochromatin, characterized by extensive subtelomeric DNA methylation and specific histone modifications. ICF (immunodeficiency, centromeric instability, facial anomalies) type I patients carry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647fe9be54c6469f6eb608adc60bd659
https://pubmed.ncbi.nlm.nih.gov/24549038
https://pubmed.ncbi.nlm.nih.gov/24549038