Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shiqun Wang"'
Autor:
Jie Dong, Lingkai Kong, Shiqun Wang, Mao Xia, Yenan Zhang, Jingyi Wu, Fuming Yang, Shuguang Zuo, Jiwu Wei
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-23 (2024)
Abstract Background Dysregulation of cholesterol metabolism is associated with the metastasis of triple-negative breast cancer (TNBC). Apolipoprotein A1 (ApoA1) is widely recognized for its pivotal role in regulating cholesterol efflux and maintainin
Externí odkaz:
https://doaj.org/article/461caec5fead425fad0d4e72172eac98
Autor:
Shiqun Wang, Wei Yan, Lingkai Kong, Shuguang Zuo, Jingyi Wu, Chunxiao Zhu, Huaping Huang, Bohao He, Jie Dong, Jiwu Wei
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract The codependency of cholesterol metabolism sustains the malignant progression of glioblastoma (GBM) and effective therapeutics remain scarce. In orthotopic GBM models in male mice, we identify that codependent cholesterol metabolism in tumor
Externí odkaz:
https://doaj.org/article/fcb79dc350dd4119b18f767f89cfcceb
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundAlthough isocitrate dehydrogenase (IDH) mutation serves as a prognostic signature for routine clinical management of glioma, nearly 90% of glioblastomas (GBM) patients have a wild-type IDH genotype (IDHWT) and lack reliable signatures to id
Externí odkaz:
https://doaj.org/article/b6666ddfdc914da7a234710f4f82531f
Autor:
Shuguang Zuo, Min Wei, Bohao He, Anxian Chen, Shiqun Wang, Lingkai Kong, Yenan Zhang, Gang Meng, Tiancheng Xu, Jingyi Wu, Fuming Yang, Hailin Zhang, Shibing Wang, Ciliang Guo, Junhua Wu, Jie Dong, Jiwu Wei
Publikováno v:
EBioMedicine, Vol 64, Iss , Pp 103240- (2021)
Background: Oncolytic virotherapy with vaccinia virus (VV) can lead to effective anti-tumor immunity by turning “cold” tumors into “hot” tumors. However, its therapeutic potential is affected by the tumor's local immunosuppressive tumor micro
Externí odkaz:
https://doaj.org/article/aba81ca101b24c53b5393f2441481244
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: The tumor microenvironment (TME) consists of heterogeneous cell populations, including malignant cells and nonmalignant cells that support tumor proliferation, invasion, and metastasis through extensive cross talk. The intra-tumor immune
Externí odkaz:
https://doaj.org/article/d66bd580d0544780aca18978d90bc2a1
Publikováno v:
Translational Pediatrics. 11:229-238
Autor:
Shiqun Wang, Jiwu Wei
Publikováno v:
International journal of cancerREFERENCES. 151(10)
Oncolytic viruses (OVs) represent a class of cancer immunotherapies that rely on hijacking the host cell factory for replicative oncolysis and eliciting immune responses for tumor clearance. An increasing evidence suggests that the metabolic state of
Autor:
Shuguang Zuo, Min Wei, Tiancheng Xu, Lingkai Kong, Bohao He, Shiqun Wang, Shibing Wang, Junhua Wu, Jie Dong, Jiwu Wei
Publikováno v:
Journal for Immunotherapy of Cancer
BackgroundIn addition to directly lysing tumors, oncolytic viruses also induce antitumor immunity by recruiting and activating immune cells in the local tumor microenvironment. However, the activation of the immune cells induced by oncolytic viruses
Autor:
Xuexia Pang, Xiyao Geng, Shiqun Wang, Jinbin Cao, Zechao Deng, Pingguang Duan, Xuechen Li, Pengying Jia, Longfei Xu
Publikováno v:
The Astrophysical Journal. 940:120
We, using the Cluster data from 2001 to 2010, studied spatial distribution of the ion polytropic index in the magnetosheath, and the modulation of polytropic process by the low-frequency disturbances (4–18 mHz). The total of 30,3283 samples is divi
Publikováno v:
Dynamic Systems and Applications. 30