Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shiqi, Long"'
Autor:
Heyong Luo, Jing Zhang, Anqing Yang, Weiwei Ouyang, Shiqi Long, Xiaojin Lin, Na Yang, Zhiru Yang, Yingchun Zhang, Yang Wei, Qiyuan Che, Yuxin Yang, Ting Guo, Xing Zhao
Publikováno v:
Bio-Protocol, Vol 13, Iss 11 (2023)
Exosomes are lipid bilayer–enclosed vesicles, actively secreted by cells, containing proteins, lipids, nucleic acids, and other substances with multiple biological functions after entering target cells. Exosomes derived from NK cells have been show
Externí odkaz:
https://doaj.org/article/1be3ff50868448b7b03b564abdb78e8f
Autor:
Heyong Luo, Yanhua Zhou, Jing Zhang, Yingchun Zhang, Shiqi Long, Xiaojin Lin, Anqing Yang, Jiangyao Duan, Na Yang, Zhiru Yang, Qiyuan Che, Yuxin Yang, Ting Guo, Dan Zi, Weiwei Ouyang, Wei Yang, Zhu Zeng, Xing Zhao
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Exosomes are membranous vesicles actively secreted by almost all cells and they deliver certain intracellular molecules, including nucleic acids, proteins, and lipids, to target cells. They are also considered to be good carriers for drug delivery du
Externí odkaz:
https://doaj.org/article/a2c56a052a3f4eebb65eebd27d52878e
Autor:
Shiqi Long, Yangzhuo Gu, Yuanyuan An, Xiaojin Lin, Xiaoqing Chen, Xianyao Wang, Chunxiang Liao, Weiwei Ouyang, Nianxue Wang, Zhixu He, Xing Zhao
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Abstract Background Cetuximab has been approved for use for first-line treatment of patients with wild-type KRAS metastatic colorectal cancer (CRC). However, treatment with cetuximab has shown limited efficacy as a CRC monotherapy. In addition, natur
Externí odkaz:
https://doaj.org/article/568cbc634d3e43c8ad84e59f27a2a9da
Autor:
Xuan Lin, Hedan Chen, Ying Xie, Xue Zhou, Yun Wang, Jing Zhou, Shiqi Long, Zuquan Hu, Shichao Zhang, Wei Qiu, Zhu Zeng, Lina Liu
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101298- (2022)
The immunosuppressive tumor microenvironment (TME) is the main reason for the failure of many immunotherapies that directly stimulate anti-tumor immune response. Anti-CTLA-4 antibody may reduce effector regulatory T (Treg) cell numbers and their supp
Externí odkaz:
https://doaj.org/article/1738c09355a74fafbf4f41324de7f28e
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0192090 (2018)
[This corrects the article DOI: 10.1371/journal.pone.0184816.].
Externí odkaz:
https://doaj.org/article/d015cb19845141b695fd0b7770c8578b
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184816 (2017)
Oncolytic viruses (OV) have recently emerged as a promising therapeutic modality in cancer treatment. OV selectively infect and kill tumor cells, while sparing untransformed cells. The direct cytotoxic effects combined with the capacity to trigger an
Externí odkaz:
https://doaj.org/article/9d14b2a5445642738f42a25155d3c8c7
Autor:
Jieheng Wu, Xinlei Liu, Jiangwei Wu, Chunju Lou, Qiaoling Zhang, Huiping Chen, Zeyang Yang, Shiqi Long, Yun Wang, Zhenling Shang, Zuquan Hu, Rui Zhang, Jian Zhang, Zhu Zeng
Publikováno v:
Biochimica et biophysica acta. Molecular basis of disease. 1868(11)
Nonsmall cell lung cancer (NSCLC) is among the most prevalent malignant tumours threatening human health. In the tumour microenvironment (TME), cancer-associated fibroblasts (CAFs) induce M2-polarized macrophages, which strongly regulate tumour progr
Autor:
Xuan Lin, Hedan Chen, Ying Xie, Xue Zhou, Yun Wang, Jing Zhou, Shiqi Long, Zuquan Hu, Shichao Zhang, Wei Qiu, Zhu Zeng, Lina Liu
Publikováno v:
Translational Oncology
Translational Oncology, Vol 15, Iss 1, Pp 101298-(2022)
Translational Oncology, Vol 15, Iss 1, Pp 101298-(2022)
Highlights • Combined therapy with MUC1 mRNA nanovaccine and anti-CTLA-4 mAb could reduce immunosuppressive TME, increase the infiltration of CD8+ T cells into tumor sites, and enhance anti-tumor cytotoxic T-lymphocyte activity when compared with e
Autor:
Chunxiang Liao, Xianyao Wang, Xiaoqing Chen, Zhixu He, Yangzhuo Gu, Xing Zhao, Yuanyuan An, Weiwei Ouyang, Nianxue Wang, Shiqi Long, Xiaojin Lin
Publikováno v:
Journal of Translational Medicine, Vol 19, Iss 1, Pp 1-14 (2021)
Journal of Translational Medicine
Journal of Translational Medicine
Background Cetuximab has been approved for use for first-line treatment of patients with wild-type KRAS metastatic colorectal cancer (CRC). However, treatment with cetuximab has shown limited efficacy as a CRC monotherapy. In addition, natural killer
Publikováno v:
Neurochemical Research. 43:736-744
Brain-derived neurotrophic factor (BDNF) is a crucial regulator to support synaptic plasticity and neuronal survival, its significant decrease is a pathophysiological hallmark in Alzheimer's disease (AD) brains and accounts for poor prognosis. MicroR