Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shiping Jiao"'
Autor:
Yanchuan Li, Huamei Li, Cheng Peng, Ge Meng, Yijun Lu, Honglin Liu, Li Cui, Huan Zhou, Zhu Xu, Lingyun Sun, Lihong Liu, Qing Xiong, Beicheng Sun, Shiping Jiao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract The structural components of the thymus are essential for guiding T cell development, but a thorough spatial view is still absent. Here we develop the TSO-his tool, designed to integrate multimodal data from single-cell and spatial transcrip
Externí odkaz:
https://doaj.org/article/25b35a0fc25f4fe490ab4c99bcd20474
Autor:
Huan Zhou, Hui Zheng, Yucai Peng, Yue Su, Xuya Yu, Weixiao Wang, Simin Li, Yuzhou Ding, Shiping Jiao, Ying Wang, Xingyu Zhu, Liping Luo, Ziyong Dong, Lu Liu, Fan Zhang, Qiang Wu, Jingxin Li, Fengcai Zhu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundWe aimed to evaluate the efficacy, safety, and immunogenicity of a SARS-CoV-2 mRNA vaccine (Omicron BA.5) LVRNA012 given as the booster in immunized but SARS-CoV-2 infection-free adults in China.MethodsThis is a single-center, randomized, d
Externí odkaz:
https://doaj.org/article/d31cc409d1d04930a4cac6989d63d08f
Autor:
Xueqi Yan, Yinghong Xie, Fan Yang, Yijia Hua, Tianyu Zeng, Chunxiao Sun, Mengzhu Yang, Xiang Huang, Hao Wu, Ziyi Fu, Wei Li, Shiping Jiao, Yongmei Yin
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-15 (2021)
Abstract Breast cancer is a heterogeneous disease with a complex microenvironment consisting of tumor cells, immune cells, fibroblasts and vascular cells. These cancer-associated cells shape the tumor microenvironment (TME) and influence the progress
Externí odkaz:
https://doaj.org/article/6ad4b17a1929406882eefd77c3e60a25
Autor:
Tong Liu, Beicheng Sun, Zhenhuang Yang, Cheng Peng, Da Pang, Shiping Jiao, Qing Xiong, Meisi Yan, Xiaolu Zhan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/e60b12ee5585499c9684afe221847977
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92172 (2014)
Our previous studies showed that BikDD, a constitutively active mutant form of Bik, exhibited powerful antitumor effects in preclinical pancreatic, lung and breast cancer models. Howerver, the antitumor activity of BikDD in triple-negative breast can
Externí odkaz:
https://doaj.org/article/e817e068951b47648d5c61d1e6df1234
Autor:
Mien-Chie Hung, Gabriel N. Hortobagyi, Banu Arun, Jennifer Litton, Shih-Shin Chang, Seung-Oe Lim, Chao-Kai Chou, Chia-Wei Li, Heng-Huan Lee, Yi Du, Wen-Hsuan Yu, Jennifer L. Hsu, Jung-Mao Hsu, Mei-Kuang Chen, Yongkun Wei, Hirohito Yamaguchi, Weiya Xia, Shiping Jiao
Supplementary Figure S1. PARPi upregulates PD-L1 in a dose-dependent manner in MD-MB-231 cells. Supplementary Figure S2. Downregulation of BRCA1 or BRCA2 has no effect on PARPi-induced PD-L1 upregulation. Supplementary Figure S3. PARPi inactivates GS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::517e1e5dc12168ae6507aec2a27442ca
https://doi.org/10.1158/1078-0432.22467021
https://doi.org/10.1158/1078-0432.22467021
Autor:
Mien-Chie Hung, Gabriel N. Hortobagyi, Banu Arun, Jennifer Litton, Shih-Shin Chang, Seung-Oe Lim, Chao-Kai Chou, Chia-Wei Li, Heng-Huan Lee, Yi Du, Wen-Hsuan Yu, Jennifer L. Hsu, Jung-Mao Hsu, Mei-Kuang Chen, Yongkun Wei, Hirohito Yamaguchi, Weiya Xia, Shiping Jiao
PARPi treatment enhances resistance to activated T-cell killing. Time-lapse video of 231 (Nuc-RFP) cells with olaparib treatment co-cultured with activated PBMCs taken using the IncuCyte Zoom microscope.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1241a409b2222359298bb0321d2ebb12
https://doi.org/10.1158/1078-0432.22467009
https://doi.org/10.1158/1078-0432.22467009
Publikováno v:
Cancer Research. 83:6665-6665
Cellular heterogeneity in the tumor immune microenvironment (TIME) of gastric cancer (GC) is progressively molded in pre- and early-malignant lesions and has a profound impact on disease progression and responses to therapeutics, in particular those
Autor:
Shiping Jiao, Qing Xiong, Meisi Yan, Xiaolu Zhan, Zhenhuang Yang, Cheng Peng, Beicheng Sun, Da Pang, Tong Liu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundSentinel lymph nodes (LNs) are regarded as key immune surveillance sites in cancer wherein mature dendritic cells present tumor-derived antigens to prime and activate T cells, which then migrate to the tumor site. However, it is unclear whe
Publikováno v:
Signal Transduction and Targeted Therapy
Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development, interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of pandemic control measures. Using HLA class I and II predicted peptide "megapools," c