Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shiou-Shiow Farn"'
Autor:
Yi-Hsiu Chung, Yi-Pei Ho, Shiou-Shiow Farn, Wei-Cheng Tsai, Zhi-Xiang Li, Tzou-Yien Lin, Chi-Chang Weng
Publikováno v:
Biomedical Journal, Vol 47, Iss 5, Pp 100721- (2024)
Extracellular vesicles derived from human umbilical cord-derived mesenchymal stem cells (UCMSC-EVs) have been postulated to have therapeutic potential for various diseases. However, the biodistribution and pharmacokinetics of these vesicles are still
Externí odkaz:
https://doaj.org/article/36a5aa49e2f34c42b77a8e407cdceb0a
Autor:
Wei-Hsi Chen, Chuang-Hsin Chiu, Shiou-Shiow Farn, Kai-Hung Cheng, Yuan-Ruei Huang, Shih-Ying Lee, Yao-Ching Fang, Yu-Hua Lin, Kang-Wei Chang
Publikováno v:
Pharmaceuticals, Vol 16, Iss 5, p 764 (2023)
Studies of the neurobiological causes of anxiety disorders have suggested that the γ-aminobutyric acid (GABA) system increases synaptic concentrations and enhances the affinity of GABAA (type A) receptors for benzodiazepine ligands. Flumazenil antag
Externí odkaz:
https://doaj.org/article/be684bcb4a89482d8ebfec1dc5fd3d9a
Autor:
Shiou-Shiow Farn, Kai-Hung Cheng, Yuan-Ruei Huang, Shih-Ying Lee, Jenn-Tzong Chen, Kang-Wei Chang
Publikováno v:
Pharmaceuticals, Vol 16, Iss 3, p 417 (2023)
Clinical studies have demonstrated that the γ-aminobutyric acid type A (GABAA) receptor complex plays a central role in the modulation of anxiety. Conditioned fear and anxiety-like behaviors have many similarities at the neuroanatomical and pharmaco
Externí odkaz:
https://doaj.org/article/a36f6f5cfafc4200b8e7992501b6332d
Autor:
Shiou-Shiow Farn, Yen-Buo Lai, Kuo-Fong Hua, Hsiang-Ping Chen, Tzu-Yi Yu, Sheng-Nan Lo, Li-Hsin Shen, Rong-Jiun Sheu, Chung-Shan Yu
Publikováno v:
Molecules, Vol 27, Iss 9, p 2850 (2022)
A small fenbufen library comprising 18 compounds was prepared via Suzuki Miyara coupling. The five-step preparations deliver 9–17% biphenyl compounds in total yield. These fenbufen analogs exert insignificant activity against the IL-1 release as we
Externí odkaz:
https://doaj.org/article/c93630b883974535a6ea985b0ad20773
Autor:
Wei-Hsi Chen, Chuang-Hsin Chiu, Shiou-Shiow Farn, Kai-Hung Cheng, Yuan-Ruei Huang, SHIH-YING LEE, Yao-Ching Fang, Yu-Hua Lin, Kang-Wei Chang
Studies on the neurobiological causes of anxiety disorders suggest that the GABA system in-creases synaptic concentration and enhances the affinity of GABAA (type A) receptors for ben-zo-diazepine ligands. Flumazenil antagonizes the benzodiazepine bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0faef7fb7ce37e8e6c7ab8412f891d7b
https://doi.org/10.20944/preprints202304.0515.v1
https://doi.org/10.20944/preprints202304.0515.v1
Autor:
Yu-Chin Tseng, Kun-Liang Lin, Wan-Chi Lin, Chung-Shan Yu, Wuu-Jyh Lin, Hung-Man Yu, Shiou-Shiow Farn, Yu Chang, Kang-Wei Chang
Publikováno v:
Drug Design, Development and Therapy.
Shiou-Shiow Farn,1,2 Kang-Wei Chang,3 Wan-Chi Lin,1 Hung-Man Yu,1 Kun-Liang Lin,1 Yu-Chin Tseng,1 Yu Chang,1 Chung-Shan Yu,2,4 Wuu-Jyh Lin1 1Isotope Application Division, Institute of Nuclear Energy Research, Taoyuan, 32546, Taiwan; 2Department of Bi
Autor:
Shiou-Shiow, Farn, Kang-Wei, Chang, Wan-Chi, Lin, Hung-Man, Yu, Kun-Liang, Lin, Yu-Chin, Tseng, Yu, Chang, Chung-Shan, Yu, Wuu-Jyh, Lin
Publikováno v:
Drug Design, Development and Therapy
Introduction Novel radiotracer development for imaging dopamine transporters is a subject of interest because although [99mTc]TRODAT-1, [123I]β-CIT, and [123I]FP-CIT are commercially available; 99Mo/99mTc generator is in short supply and 123I produc
Autor:
Yi-Hsiu Chung, Chun-Nan Yeh, Shi-Wei Tien, Chung-Shan Yu, Yong-Ren Chen, Shiou-Shiow Farn, Tsung-Wen Chen, Ying-Cheng Huang, Chi-Wei Chang
Publikováno v:
Drug Design, Development and Therapy. 12:1467-1478
Background An 18F-tagged NSAID analog was prepared for use as a probe for COX-2 expression, which is associated with tumor development. Methods The in vivo uptake of celecoxib was monitored with ortho-[18F]fluorocelecoxib using positron emission tomo
Autor:
Chun-Nan Yeh, Chi-Wei Chang, Chung-Shan Yu, Tsong-Wen Chen, Shiou-Shiow Farn, Yi-Hsiu Chung, Yo-Cheng Chou, Wen-Sheng Huang, Ying-Cheng Huang
Publikováno v:
Journal of the Chinese Chemical Society. 65:780-792
Autor:
Yuen-Han Yeh, Shiou-Shiow Farn, Wuu-Jyh Lin, Chung-Shan Yu, Jenn-Tzong Chen, Ching-Shiuann Yang, Chang-Chin Li
Publikováno v:
Applied Radiation and Isotopes. 127:61-67
[123I]IBZM is used widely for in vivo imaging of D2 receptors in human brain and shows relatively fast kinetics and a greater susceptibility to synaptic dopamine release than other single-photon emission computed tomography (SPECT) radioligands. A re