Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Shiona M. Laing"'
Autor:
Shaun G. Goodman, Elliott C. Norry, Shiona M. Laing, Robert P. Giugliano, Mikael Dellborg, Tara C. Barker, Kathryn Starzyk, P. Gabriel Steg, Jill E. Abell
Publikováno v:
European Heart Journal - Cardiovascular Pharmacotherapy. 3:214-220
Aim This retrospective chart review was designed to evaluate physician adherence to the prescribing information for fondaparinux regarding adjunctive anticoagulant use during percutaneous coronary intervention (PCI) in patients with an acute coronary
Autor:
Michael E. Parsons, Leach Colin Andrew, Kenneth Wiggall, David J. Keeling, Thomas Henry Brown, Carolyn A. Price, Shiona M. Laing, Robert John Ife
Publikováno v:
Journal of Medicinal Chemistry. 35:1845-1852
Further work on compounds 1 has identified the 4-position as a site where substantial modifications are tolerated, leading to analogues which are more potent and less toxic than those described previously. The best compound in the series is 13a (SK&F
Publikováno v:
Biochemical Pharmacology. 39:1799-1806
The mechanism by which the substituted benzimidazole sulphoxide BY 1023/SKF 96022 inhibited the (H+ + K+)-ATPase, the enzyme responsible for hydrogen ion secretion in the stomach, was studied in a variety of in vitro preparations. In gastric preparat
Autor:
Dominique P. Germain, Fatih Süheyl Ezgü, Sheela Sitaraman, Claudio Feliciani, Pol Boudes, Rosemary Schroyer, Suma P. Shankar, Alexander Bragat, Salim Janmohamed, Kathy Nicholls, Shiona M. Laing
Publikováno v:
Molecular Genetics and Metabolism. 108:S70
Autor:
Shiona M. Laing, Janice Pogue, Shamir R. Mehta, Sunil V. Rao, Susan Chrolavicius, Jose Lopez-Sendon, Hans-Juergen Rupprecht, Christopher B. Granger, Philippe Gabriel Steg, Salim Yusuf, Denis Xavier, Sanjit S. Jolly
Publikováno v:
American Heart Journal. 160:1029-1034.e1
Background There is uncertainty regarding the optimal adjunctive unfractionated heparin (UFH) regimen for percutaneous coronary intervention (PCI) in patients with non–ST-segment elevation acute coronary syndrome (NSTE-ACS) treated with fondaparinu
Autor:
Leach Colin Andrew, Kenneth Wiggall, David R. Reavill, David J. Keeling, Shiona M. Laing, Thomas Henry Brown, Robert John Ife, Michael E. Parsons, Carolyn A. Price
Publikováno v:
Journal of medicinal chemistry. 33(2)
The 4-(arylamino)quinoline 4, previously described as an antiulcer compound, is shown to be an inhibitor of the gastric (H+/K+)-ATPase. It is postulated that 1-arylpyrrolo[3,2-c]quinolines 6 act as conformationally restrained analogues of 4. A series
Publikováno v:
Biochemical pharmacology. 37(11)
SCH 28080 (2-methyl-8-(phenylmethoxy)imidazo[1,2-a]pyridine-3-acetonitrile) is an effective inhibitor of acid secretion in vivo and is a reversible, K+-competitive inhibitor of the gastric (H+ + K+)-ATPase in vitro. The actions of SCH 28080 have been
Autor:
David J. Keeling, Shiona M. Laing
Publikováno v:
Biochemical Society Transactions. 15:1139-1140
Publikováno v:
Biochemical Society Transactions. 15:693-694
Publikováno v:
Biochemical Society Transactions. 15:694-695