Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Shinzaburo Minami"'
Publikováno v:
Journal of Infection and Chemotherapy. 9:144-150
The therapeutic efficacy of amphotericin B (AmB), imipenem/cilastatin (IPM/CS), pazufloxacin (PZFX) mesilate, and combinations of these, was evaluated using an experimental pulmonary superinfection model in mice caused by Pseudomonas aeruginosa and A
Autor:
Yukihiko Oishi, Masahiro Takahata, Satoshi Ameyama, Shoichi Onodera, Nobuko Maki, Shinzaburo Minami, Katsuhisa Endo, Hiroo Suzuki, Hirokazu Goto
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:3744-3749
Neisseria gonorrhoeae strains with reduced susceptibility to cefixime (MICs, 0.25 to 0.5 μg/ml) were isolated from male urethritis patients in Tokyo, Japan, in 2000 and 2001. The resistance to cephems including cefixime and penicillin was transferre
Autor:
Hiroyuki Egawa, Yasuo Watanabe, Kazumi Takahashi, Shinzaburo Minami, Kyo Kozaki, M. Kuno, Kimiyasu Shiraki, Yoshiko Fukuda, T. Kamiyama, Nobuhiko Nomura, Yousuke Furuta, H. Narita
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:977-981
T-705 (6-fluoro-3-hydroxy-2-pyrazinecarboxamide) has been found to have potent and selective inhibitory activity against influenza virus. In an in vitro plaque reduction assay, T-705 showed potent inhibitory activity against influenza A, B, and C vir
Autor:
Naoko Ogake, Harumi Araki, Ikumi Tamai, Reiko Tsuneda, Shinzaburo Minami, Akira Tsuji, Yasuo Watanabe
Publikováno v:
Drug Metabolism and Pharmacokinetics. 17:237-244
The purpose of this study was to evaluate the distribution of three fluoroquinolones (pazufloxacin, ciprofloxacin and ofloxacin) and a beta-lactam, ceftazidime in the tissue interstitial and intracellular spaces after a single intravenous administrat
Publikováno v:
Journal of Antimicrobial Chemotherapy. 45:311-314
The therapeutic effects of parenteral beta-lactam antibiotics were evaluated in experimental acute otitis media caused by penicillin-resistant Streptococcus pneumoniae (PRSP) in guinea-pigs. Cefotaxime, ceftriaxone and piperacillin significantly redu
Autor:
Harumi Araki, Yozo Todo, Yasuo Watanabe, Shinzaburo Minami, Masahiro Takahata, Minoru Yonezawa, Yoshiko Yamashiro, Junichi Mitsuyama, Hirokazu Narita
Publikováno v:
Antimicrobial Agents and Chemotherapy. 43:1077-1084
The in vitro and in vivo activities of T-3811ME, a novel des-F(6)-quinolone, were evaluated in comparison with those of some fluoroquinolones, including a newly developed one, trovafloxacin. T-3811, a free base of T-3811ME, showed a wide range of ant
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:176-179
Genes for two group 1 β-lactamases, SRT-1 and SST-1, were sequenced. These β-lactamases were produced by clinical isolates of Serratia marcescens , isolates GN16694 and GN19450, respectively. The resulting enzymes were 96% identical. SRT-1 hydrolyz
Autor:
J Maehana, Hisashi Yamada, Y Todo, S Kurose, Hirokazu Narita, Junichi Mitsuyama, Yasuo Watanabe, Shinzaburo Minami, Yoshiko Fukuda
Publikováno v:
Journal of Antimicrobial Chemotherapy. 39:697-705
Exposure of Staphylococcus aureus to 1 x MIC of the quinolone antibiotic pazufloxacin for 24 h, followed by plating on drug-free media, led to the emergence of small colony variants (SCVs) in addition to large colony variants (LCVs). However, followi
Publikováno v:
Journal of Infection & Chemotherapy (Springer Science & Business Media B.V.); Apr2003, Vol. 9 Issue 2, p144-150, 7p
Publikováno v:
Journal of Antimicrobial Chemotherapy. 39:31-34
The in-vitro activity of T-5575, 2-carboxypenam, a new parenteral antibiotic and its stability to beta-lactamases were compared with those of ceftazidime and imipenem. The activity of T-5575 was equal or superior to that of ceftazidime or imipenem ag