Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shinya Yari"'
Autor:
Kotaro Shimizu, Junichi Kikuta, Yumi Ohta, Yutaka Uchida, Yu Miyamoto, Akito Morimoto, Shinya Yari, Takashi Sato, Takefumi Kamakura, Kazuo Oshima, Ryusuke Imai, Yu-Chen Liu, Daisuke Okuzaki, Tetsuya Hara, Daisuke Motooka, Noriaki Emoto, Hidenori Inohara, Masaru Ishii
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Cholesteatoma, which potentially results from tympanic membrane retraction, is characterized by intractable local bone erosion and subsequent hearing loss and brain abscess formation. However, the pathophysiological mechanisms underlying bon
Externí odkaz:
https://doaj.org/article/c71521675c2341f09d2da9b81a447aaf
Autor:
Shinya Yari, Junichi Kikuta, Hotaka Shigyo, Yu Miyamoto, Daisuke Okuzaki, Yuki Furusawa, Masafumi Minoshima, Kazuya Kikuchi, Masaru Ishii
Publikováno v:
Inflammation and Regeneration, Vol 43, Iss 1, Pp 1-12 (2023)
Abstract Background Rheumatoid arthritis (RA) is characterized by chronic inflammation and resultant cartilage/bone destruction because of aberrantly activated osteoclasts. Recently, novel treatments with several Janus kinase (JAK) inhibitors have be
Externí odkaz:
https://doaj.org/article/51e5fbc3956d46cea4ef7601f6b0857c
Arthritis-associated osteoclastogenic macrophage, AtoM, as a key player in pathological bone erosion
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-6 (2022)
Abstract Osteoclasts are myeloid lineage cells with a unique bone-destroying ability that maintains bone homeostasis together with bone formation by osteoblasts. An advanced intravital imaging system using a two-photon microscopy has enabled the obse
Externí odkaz:
https://doaj.org/article/5b8b23aede3e443c9c7d1692da2e30a9
Publikováno v:
Immunological Medicine, Vol 45, Iss 1, Pp 22-26 (2022)
Rheumatoid arthritis is a chronic form of arthritis that causes bone destruction in joints such as the knees and fingers. Over the past two decades, the clinical outcomes of rheumatoid arthritis have improved substantially with the development of bio
Externí odkaz:
https://doaj.org/article/c315b6fe4b224f82b8909702e9a0b3ae
Autor:
Takuya Koike, Kentaro Fujii, Kohei Kometani, Noah S. Butler, Kenji Funakoshi, Shinya Yari, Junichi Kikuta, Masaru Ishii, Tomohiro Kurosaki, Wataru Ise
Publikováno v:
The Journal of experimental medicine. 220(2)
The longevity of plasma cells is dependent on their ability to access and reside in so-called niches that are predominantly located in the bone marrow. Here, by employing a traceable method to label recently generated plasma cells, we showed that hom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::241ad25bd825fd447aef61c52e83fe4b
https://pubmed.ncbi.nlm.nih.gov/36515679
https://pubmed.ncbi.nlm.nih.gov/36515679
Publikováno v:
Seibutsu Butsuri. 60:227-230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::988ce2367be81a79cd0d8c0623afafcf
https://doi.org/10.2142/biophys.60.227
https://doi.org/10.2142/biophys.60.227
Publikováno v:
Immunological Medicine, Vol 0, Iss 0, Pp 1-5 (2021)
Rheumatoid arthritis is a chronic form of arthritis that causes bone destruction in joints such as the knees and fingers. Over the past two decades, the clinical outcomes of rheumatoid arthritis have improved substantially with the development of bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42ba7fc62380f31c6410eef260a8b6ae
https://pubmed.ncbi.nlm.nih.gov/34187325
https://pubmed.ncbi.nlm.nih.gov/34187325
Autor:
Ryu Hashimoto, Masaru Ishii, Masafumi Minoshima, Junichi Kikuta, Steven D. Bull, Kazuya Kikuchi, Shinya Yari
Publikováno v:
Angewandte Chemie (International Ed. in English)
A rationally designed pH‐activatable fluorescent probe (pHocas‐RIS) has been used to measure localised pH levels in osteocytic lacunae in bone tissue. Conjugation of the moderate bone‐binding drug risedronate to a pH‐activatable BODIPY fluoro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebc4ca8d6b4a08859017d308a372f6c
https://pubmed.ncbi.nlm.nih.gov/32744428
https://pubmed.ncbi.nlm.nih.gov/32744428