Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Shinya Usui"'
Autor:
Shinya Usui, Qiunan Zhu, Hisakazu Komori, Yui Iwamoto, Takumi Nishiuchi, Yoshiyuki Shirasaka, Ikumi Tamai
Publikováno v:
Drug Metabolism and Pharmacokinetics. :100512
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b83c16269cf1e664d819bb8b26af420
https://doi.org/10.1016/j.dmpk.2023.100512
https://doi.org/10.1016/j.dmpk.2023.100512
Publikováno v:
Netsu Bussei. 27:69-76
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55352ec31aa75f758b2936b7c78f5c8e
https://doi.org/10.2963/jjtp.27.69
https://doi.org/10.2963/jjtp.27.69
Autor:
Norio Fujiwara, Yoshiharu Uruno, Shinya Usui, Atsushi Suwa, Akio Tanaka, Kazuki Hashimoto, Kentaro Takai, Wataru Katoda, Yasuko Konishi, Takaaki Sumiyoshi, Yasunao Inoue
Publikováno v:
Tetrahedron. 69:9675-9681
N , N -Dimethylcarbamoylation of the anilinic nitrogen atom N(1) on the spiro 7-azaindoline consists of two steps. The first step is N , N -dimethylcarbamoylation of the pyridyl nitrogen atom N(7), leading to the formation of an isolable intermediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28cfdcc779cdfb6f31d9d5d853a53a73
https://doi.org/10.1016/j.tet.2013.09.024
https://doi.org/10.1016/j.tet.2013.09.024
Autor:
Yotaro Matsumoto, Ryo Takita, Masanobu Uchiyama, Andrew E. H. Wheatley, Shinya Usui, Keiichi Hirano, Joanna Haywood, Shinsuke Komagawa, Philip J. Harford
Publikováno v:
Angewandte Chemie International Edition. 51:12081-12085
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60ad3cc360aa70bfe84f5281c01d268b
https://doi.org/10.1002/anie.201204923
https://doi.org/10.1002/anie.201204923
Autor:
Masanobu Uchiyama, Yoshihisa Tanaka, Manabu Sami, Daiki Honma, Toyokazu Yokota, Motoyuki Tagashira, Masanobu Kirita, Mari Maeda-Yamamoto, Tomomasa Kanda, Shinya Usui, Toshihiko Shoji, Atsuya Muranaka
Publikováno v:
Journal of Agricultural and Food Chemistry. 58:7196-7201
The gene of a novel O-methyltransferase was isolated from tea cultivars (Camellia sinensis L.). Using the recombinant enzyme, O-methylated (-)-epigallocatechin-3-O-gallate (EGCG) in all cases were synthesized. EGCG and the synthesized O-methylated EG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838aabf79c7f4b2e300116d764ea79ea
https://doi.org/10.1021/jf100493s
https://doi.org/10.1021/jf100493s
Autor:
Hidehiko Nakagawa, Hiroki Fujieda, Shinya Usui, Makoto Makishima, Takayoshi Suzuki, Naoki Miyata, Michitaka Ogura
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:4351-4357
To find novel PPARdelta-selective agonists, we designed and synthesized phenylpropanoic acid derivatives bearing 6-substituted benzothiazoles. Optimization of this series led to the identification of a potent and selective PPARdelta agonist 17. Molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945cf4d2430154b7076b4c5b4485595b
https://doi.org/10.1016/j.bmcl.2007.05.017
https://doi.org/10.1016/j.bmcl.2007.05.017
Publikováno v:
Advanced Synthesis & Catalysis. 349:595-600
Theoretical studies on the chemo- and regioselective ortho-oxidation reaction of phenols mediated by a biomimetic μ-η:η 2 peroxo)dicopper(II) complex were performed using unrestricted hybrid density functional theory (UB3LYP) calculations, with th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1bd9e7e27fc1558fb8449c1cd7ce14c
https://doi.org/10.1002/adsc.200600557
https://doi.org/10.1002/adsc.200600557
Publikováno v:
Angewandte Chemie International Edition. 46:926-929
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cf21ee3c681f6903870493760a4d08
https://doi.org/10.1002/anie.200602664
https://doi.org/10.1002/anie.200602664
Autor:
Shinya Usui, Naoaki Yoshida, Takayoshi Suzuki, Naoki Miyata, Hiroki Fujieda, Hidehiko Nakagawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:3249-3254
To develop novel PPARalpha ligands, we designed and synthesized several 3-{3-[2-(nonylpyridin-2-ylamino)ethoxy]phenyl}propanoic acid derivatives. Compound 10, the meta isomer of a PPARgamma agonist 1, has been identified as a PPARalpha ligand. The in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eadea86f1db3c9c7dd46c6d405f48ebf
https://doi.org/10.1016/j.bmcl.2006.03.031
https://doi.org/10.1016/j.bmcl.2006.03.031
Autor:
Kazuma Etoh, Hiroki Fujieda, Masayoshi Imagawa, Yoshifumi Hattori, Takayoshi Suzuki, Kohfuku Kohda, Naoki Miyata, Hidehiko Nakagawa, Shinya Usui, Makoto Nishizuka
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1547-1551
To develop novel PPARγ ligands, we synthesized thirteen 3-{4-(2-aminoethoxy)phenyl}propanoic acid derivatives, which are designed based on the structures of rosiglitazone and 15d-PGJ2. Among these compounds, compound 9 was found to be as potent as r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf6135d017fa984c2ec1f560a0e3e0c
https://doi.org/10.1016/j.bmcl.2005.01.074
https://doi.org/10.1016/j.bmcl.2005.01.074