Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Shinya Tsurusaki"'
Autor:
Yuichi Tsuchiya, Takao Seki, Kenta Kobayashi, Sachiko Komazawa-Sakon, Shigeyuki Shichino, Takashi Nishina, Kyoko Fukuhara, Kenichi Ikejima, Hidenari Nagai, Yoshinori Igarashi, Satoshi Ueha, Akira Oikawa, Shinya Tsurusaki, Soh Yamazaki, Chiharu Nishiyama, Tetuo Mikami, Hideo Yagita, Ko Okumura, Taketomo Kido, Atsushi Miyajima, Kouji Matsushima, Mai Imasaka, Kimi Araki, Toru Imamura, Masaki Ohmuraya, Minoru Tanaka, Hiroyasu Nakano
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Liver fibrosis results from chronic liver injury triggered by factors such as viral infection, excess alcohol intake, and lipid accumulation. However, the mechanisms underlying liver fibrosis are not fully understood. Here, we demonstrate th
Externí odkaz:
https://doaj.org/article/634090b816f84d4c88ef880ddf06cc84
Autor:
Cindy Y. Kok, Shinya Tsurusaki, Marti Cabanes-Creus, Sindhu Igoor, Renuka Rao, Rhys Skelton, Sophia H.Y. Liao, Samantha L. Ginn, Maddison Knight, Suzanne Scott, Mario Mietzsch, Rebecca Fitzsimmons, Jessica Miller, Tamer M.A. Mohamed, Robert McKenna, James J.H. Chong, Adam P. Hill, James E. Hudson, Ian E. Alexander, Leszek Lisowski, Eddy Kizana
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 30, Iss , Pp 459-473 (2023)
Recombinant adeno-associated viruses (rAAVs) have emerged as one of the most promising gene therapy vectors that have been successfully used in pre-clinical models of heart disease. However, this has not translated well to humans due to species diffe
Externí odkaz:
https://doaj.org/article/0a04499d5cb345478b523f2075186f26
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1397 (2023)
Lentiviral vectors are a robust gene delivery tool for inducing transgene expression in a variety of cells. They are well suited to facilitate the testing of therapeutic candidate genes in vitro, due to relative ease of packaging and ability to trans
Externí odkaz:
https://doaj.org/article/f5793444a29442c0a773f4acf2110ede
Autor:
Yasushi Miura, Satoshi Matsui, Naoko Miyata, Kenichi Harada, Yamato Kikkawa, Masaki Ohmuraya, Kimi Araki, Shinya Tsurusaki, Hitoshi Okochi, Nobuhito Goda, Atsushi Miyajima, Minoru Tanaka
Publikováno v:
eLife, Vol 7 (2018)
Under chronic or severe liver injury, liver progenitor cells (LPCs) of biliary origin are known to expand and contribute to the regeneration of hepatocytes and cholangiocytes. This regeneration process is called ductular reaction (DR), which is accom
Externí odkaz:
https://doaj.org/article/5679f347df954026b77abb2e1e3c6b47
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2455
Nonalcoholic steatohepatitis (NASH) is a metabolic liver disease that progresses from simple steatosis to the disease states such as chronic inflammation and fibrosis. In most liver diseases, immunological responses caused by tissue damages or viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a08c0c3ef98edec5a0d60a6ead17ffa
https://pubmed.ncbi.nlm.nih.gov/35213001
https://pubmed.ncbi.nlm.nih.gov/35213001
Publikováno v:
Methods in Molecular Biology ISBN: 9781071621271
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19e23fcde5b59e97d1eb8be11a15fd0c
https://doi.org/10.1007/978-1-0716-2128-8_21
https://doi.org/10.1007/978-1-0716-2128-8_21
Autor:
Eiko Saijou, Michitaka Matsuda, Minoru Tanaka, Hitoshi Okochi, Atsushi Miyajima, Naoko Miyata, Shinya Tsurusaki
Publikováno v:
Hepatology. 67:296-312
Fibrosis is an important wound-healing process in injured tissues, but excessive fibrosis is often observed in patients with chronic inflammation. Although oncostatin M (OSM) has been reported to play crucial roles for recovery from acute liver injur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66317fdf214bfec3c6b6e3eb0874a85
https://doi.org/10.1002/hep.29421
https://doi.org/10.1002/hep.29421
Autor:
Shinya Tsurusaki, Mehwish Khaliq, Minoru Tanaka, Tae-Young Choi, Didier Y.R. Stainier, Nikolay Ninov, Donghun Shin
Publikováno v:
Hepatology. 66:1616-1630
Upon mild liver injury, new hepatocytes originate from pre-existing hepatocytes. However, if hepatocyte proliferation is impaired, a manifestation of severe liver injury, biliary epithelial cells (BECs) contribute to new hepatocytes through BEC dedif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e09f25d8b9e0a06c4284094d13ae769c
https://doi.org/10.1002/hep.29309
https://doi.org/10.1002/hep.29309
Autor:
Hitoshi Okochi, Hiroyasu Nakano, Cindy Kok, Masaki Matsuoka, Taro Sakamoto, Shinya Tsurusaki, Minoru Tanaka, Misaki Nakasone, Atsushi Miyajima, Tomoko Koumura, Yuichi Tsuchiya, Hirotaka Imai
Publikováno v:
Cell Death and Disease, Vol 10, Iss 6, Pp 1-14 (2019)
Cell Death & Disease
Cell Death & Disease
Nonalcoholic steatohepatitis (NASH) is a metabolic liver disease that progresses from simple steatosis to the disease state of inflammation and fibrosis. Previous studies suggest that apoptosis and necroptosis may contribute to the pathogenesis of NA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309a5bc8b4a818ccf38f9c9856ede74b
https://doi.org/10.1038/s41419-019-1678-y
https://doi.org/10.1038/s41419-019-1678-y
Autor:
Kimi Araki, Hitoshi Okochi, Minoru Tanaka, Nobuhito Goda, Masaki Ohmuraya, Satoshi Matsui, Shinya Tsurusaki, Naoko Miyata, Kenichi Harada, Atsushi Miyajima, Yasushi Miura, Yamato Kikkawa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a35edaa26b7aab1c9c7705a27978c6c
https://doi.org/10.7554/elife.36572.033
https://doi.org/10.7554/elife.36572.033