Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shinya Tomita"'
Autor:
Yusuke Higuchi, Takehiro Ogata, Naohiko Nakanishi, Masahiro Nishi, Yumika Tsuji, Shinya Tomita, Simon J. Conway, Satoaki Matoba
Publikováno v:
ESC Heart Failure, Vol 11, Iss 1, Pp 167-178 (2024)
Abstract Aims Transforming growth factor β (TGF‐β) signalling is one of the critical pathways in fibroblast activation, and several drugs targeting the TGF‐β/Smad signalling pathway in heart failure with cardiac fibrosis are being tested in cl
Externí odkaz:
https://doaj.org/article/1f696defc25a4617be70ccf2ee9d82dd
Autor:
Shinya Tomita, Naohiko Nakanishi, Takehiro Ogata, Yusuke Higuchi, Akira Sakamoto, Yumika Tsuji, Takaomi Suga, Satoaki Matoba
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-15 (2024)
Abstract Caveolin-1 (CAV1) and Cavin-1 are components of caveolae, both of which interact with and influence the composition and stabilization of caveolae. CAV1 is associated with pulmonary arterial hypertension (PAH). Bone morphogenetic protein (BMP
Externí odkaz:
https://doaj.org/article/de8e1a3535fd491ba09fa170f43afce9
Autor:
Takeru Kasahara, Takehiro Ogata, Naohiko Nakanishi, Shinya Tomita, Yusuke Higuchi, Naoki Maruyama, Tetsuro Hamaoka, Satoaki Matoba
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17193- (2023)
Pulmonary hypertension (PH) is associated with a poor prognosis even in recent years. Caveolin-1 (CAV1), a caveolae-associated protein, is a causal gene in PH. Cavin-2, one of the other caveolae-associated proteins, forms protein complexes with CAV1
Externí odkaz:
https://doaj.org/article/44f34dc85fe046b5865fec0f97ed0922
Autor:
Masahiro Nishi, Takehiro Ogata, Ko Kobayakawa, Reiko Kobayakawa, Tomohiko Matsuo, Carlo Vittorio Cannistraci, Shinya Tomita, Shunta Taminishi, Takaomi Suga, Tomoya Kitani, Yusuke Higuchi, Akira Sakamoto, Yumika Tsuji, Tomoyoshi Soga, Satoaki Matoba
Publikováno v:
ESC Heart Failure, Vol 9, Iss 1, Pp 428-441 (2022)
Abstract Aims Cardiac ischaemia/reperfusion (I/R) injury remains a critical issue in the therapeutic management of ischaemic heart failure. Although mild hypothermia has a protective effect on cardiac I/R injury, more rapid and safe methods that can
Externí odkaz:
https://doaj.org/article/410d4334202946b9bf498e8531456aae
Requirement of Cavin-2 for the expression and stability of IRβ in adequate adipocyte differentiation
Autor:
Yusuke Higuchi, Takehiro Ogata, Naohiko Nakanishi, Masahiro Nishi, Akira Sakamoto, Yumika Tsuji, Shinya Tomita, Satoaki Matoba
Publikováno v:
Molecular Metabolism, Vol 55, Iss , Pp 101416- (2022)
Objective: Adipogenesis plays an essential role in maintaining energy and hormonal balance. Cavin-2, one of the caveolae-related proteins, is abundant in adipocytes, the leading site of adipogenesis. However, the details of the roles of Cavin-2 in ad
Externí odkaz:
https://doaj.org/article/9a853de239b54c09b1e17b0db118fd77
Autor:
Shinya Tomita, Naohiko Nakanishi, Takehiro Ogata, Yusuke Higuchi, Akira Sakamoto, Yumika Tsuji, Takaomi Suga, Satoaki Matoba
Caveolin-1 (CAV1) and Cavin-1 are components of caveolae, both of which interact with and influence the composition and stabilization of caveolae. CAV1 is associated with pulmonary arterial hypertension (PAH). Bone morphogenetic protein (BMP) type 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f08d130e65e3080acee8fc374ab4c407
https://doi.org/10.21203/rs.3.rs-2529507/v1
https://doi.org/10.21203/rs.3.rs-2529507/v1
Autor:
Satoaki Matoba, Yusuke Higuchi, Masahiro Nishi, Akira Sakamoto, Tomoyoshi Soga, Carlo Vittorio Cannistraci, Yumika Tsuji, Shunta Taminishi, Shinya Tomita, Tomoya Kitani, Takaomi Suga, Tomohiko Matsuo, Ko Kobayakawa, Reiko Kobayakawa, Takehiro Ogata
Publikováno v:
ESC Heart Failure
ESC Heart Failure, Vol 9, Iss 1, Pp 428-441 (2022)
ESC Heart Failure, Vol 9, Iss 1, Pp 428-441 (2022)
Aims Cardiac ischaemia/reperfusion (I/R) injury remains a critical issue in the therapeutic management of ischaemic heart failure. Although mild hypothermia has a protective effect on cardiac I/R injury, more rapid and safe methods that can obtain si
Autor:
Takehiro Ogata, Satoaki Matoba, Yumika Tsuji, Akira Sakamoto, Shinya Tomita, Yusuke Higuchi, Naohiko Nakanishi, Takaomi Suga
Publikováno v:
European Heart Journal. 42
Background Pulmonary hypertension (PH) is a progressive disease associated with poor outcomes. Caveolin-1 (Cav1) and Cavin-1 are components of caveolae, and Cav1 is identified as a related gene of pulmonary arterial hypertension (PAH). Gene mutations
Autor:
Yumika Tsuji, Yusuke Higuchi, Naohiko Nakanishi, Shinya Tomita, Takehiro Ogata, Satoaki Matoba, Akira Sakamoto
Publikováno v:
European Heart Journal. 41
Background Abdominal aortic aneurysm (AAA) is a common and life-threatening vascular disease. The initial phase of AAA progression is vascular inflammation. Inflammation sites present adhesion molecules, such as vascular cell adhesion molecule-1 (VCA
Autor:
Naohiko Nakanishi, Satoaki Matoba, Yusuke Higuchi, Takehiro Ogata, Yumika Tsuji, Shinya Tomita, Akira Sakamoto
Publikováno v:
Circulation Research. 127
Introduction: Heart failure (HF) is a progressive disease associated with high morbidity and mortality. A major cause of HF is the adverse tissue remodeling with interstitial fibrosis. Excessive extracellular matrix (ECM) accumulation is involved in