Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Shinya Takahata"'
Autor:
Shinya Takahata, Yota Murakami
Publikováno v:
Biomolecules, Vol 13, Iss 2, p 377 (2023)
DNA is stored in the nucleus of a cell in a folded state; however, only the necessary genetic information is extracted from the required group of genes. The key to extracting genetic information is chromatin ambivalence. Depending on the chromosomal
Externí odkaz:
https://doaj.org/article/09dbdcc63bd148169e08f456ed5ecbb9
Autor:
Masato Sorida, Takahiro Hirauchi, Hiroaki Ishizaki, Wataru Kaito, Atsushi Shimada, Chie Mori, Yuji Chikashige, Yasushi Hiraoka, Yutaka Suzuki, Yasuyuki Ohkawa, Hiroaki Kato, Shinya Takahata, Yota Murakami
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008129 (2019)
H3K9 methylation (H3K9me) is a conserved marker of heterochromatin, a transcriptionally silent chromatin structure. Knowledge of the mechanisms for regulating heterochromatin distribution is limited. The fission yeast JmjC domain-containing protein E
Externí odkaz:
https://doaj.org/article/2099b0449c92434ba6b2b5851b91df00
Autor:
Warren P Voth, Shinya Takahata, Joy L Nishikawa, Benjamin M Metcalfe, Anders M Näär, David J Stillman
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e84092 (2014)
Xenobiotic drugs induce Pleiotropic Drug Resistance (PDR) genes via the orthologous Pdr1/Pdr3 transcription activators. We previously identified the Mediator transcription co-activator complex as a key target of Pdr1 orthologs and demonstrated that P
Externí odkaz:
https://doaj.org/article/1fd3f81dca21407fba51ebbd85ca3e7e
Publikováno v:
Genes to Cells. 27:93-112
H2A.Z, an evolutionally well-conserved histone H2A variant, is involved in many biological processes. Although the function of H2A.Z in euchromatic gene regulation is well known, its function and deposition mechanism in heterochromatin are still uncl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f463202dbf1f8efaa2c13576fddce312
https://doi.org/10.1111/gtc.12911
https://doi.org/10.1111/gtc.12911
Autor:
Motoyoshi Ando, Shinya Takahata, Atsushi Shimada, Yota Murakami, Hiroki Yu, Tomoka Hashizaki, Mai Tsuchida
Publikováno v:
Genes to Cells. 26:203-218
In fission yeast, siRNA generated by RNA interference (RNAi) factors plays critical roles in establishment and maintenance of heterochromatin. To achieve efficient siRNA synthesis, RNAi factors assemble on heterochromatin via association with Swi6, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07362fc53cc69479d65799a19220ae7a
https://doi.org/10.1111/gtc.12833
https://doi.org/10.1111/gtc.12833
Publikováno v:
Yeast. 38:251-261
Gene expression vectors are useful and important tools that are commonly used in a variety of experiments, including expression of foreign genes, functional analysis of genes of interest and complementation experiments. In this study, a hybrid promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f48f7fa1e44f4ce5da3c2b2f01a181
https://doi.org/10.1002/yea.3539
https://doi.org/10.1002/yea.3539
Publikováno v:
Genes & Genetic Systems. 94:51-59
Transcription factor II D (TFIID), a multiprotein complex consisting of TATA-binding protein (TBP) and 13-14 TBP-associated factors (Tafs), plays a central role in transcription and regulates nearly all class II genes. The N-terminal domain of Taf1p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8bebfa59f45b5be3cc4bed062b18a36b
https://doi.org/10.1266/ggs.19-00001
https://doi.org/10.1266/ggs.19-00001
Publikováno v:
Cell Reports. 36:109540
FACT (facilitate chromatin transcription) is involved in heterochromatic silencing, but its mechanisms and function remain unclear. We reveal that the Spt16 recruitment mechanism operates in two distinct ways in heterochromatin. First, Pob3 mediates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a75219cc97a0851154f1d8ac149f72a
https://doi.org/10.1016/j.celrep.2021.109540
https://doi.org/10.1016/j.celrep.2021.109540
Autor:
Shinya Takahata, Hiroaki Kato, Yasuyuki Ohkawa, Atsushi Shimada, Yasushi Hiraoka, Yuji Chikashige, Hiroaki Ishizaki, Yutaka Suzuki, Yota Murakami, Masato Sorida, Takahiro Hirauchi, Chie Mori, Wataru Kaito
Publikováno v:
PLoS Genetics, Vol 15, Iss 6, p e1008129 (2019)
PLoS Genetics
PLoS Genetics
H3K9 methylation (H3K9me) is a conserved marker of heterochromatin, a transcriptionally silent chromatin structure. Knowledge of the mechanisms for regulating heterochromatin distribution is limited. The fission yeast JmjC domain-containing protein E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc71eb9a5ed1826a661c1259b3e52a7
http://ir.lib.shimane-u.ac.jp/52582
http://ir.lib.shimane-u.ac.jp/52582
Publikováno v:
Transcription. 8:26-31
Epigenetic marks determine cell fate via numerous reader proteins. H3K36 methylation is a common epigenetic mark that is thought to be associated with the activities of the RNA polymerase 2 C-terminal domain. We discuss a novel silencing mechanism re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37bb0b0897b3245a65bf938c87b0bbd
https://doi.org/10.1080/21541264.2016.1246076
https://doi.org/10.1080/21541264.2016.1246076