Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shinya Sehata"'
Publikováno v:
International Journal of Molecular Sciences, Vol 9, Iss 11, Pp 2146-2158 (2008)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
T-2 toxin is a cytotoxic secondary fungal metabolite that belongs to the trichothecene mycotoxin family. This mycotoxin is a well known inhibitor of protein synthesis through its high binding affinity to peptidyl transferase, which is an integral par
Autor:
Kazuyoshi Kumagai, Sunao Manabe, Munehiro Teranishi, Takanori Maejima, Shinya Sehata, Makoto Shirai, Toshihiko Makino
Publikováno v:
Journal of Toxicologic Pathology. 21:109-113
A pulmonary mass was observed in a 16-year-old beagle dog. In the histopathology, a well-circumscribed mass composed of cuboidal to low or tall columnar neoplastic cells proliferating in a papillary, acinar or solid pattern and abundant cholesterin d
Autor:
Fusako Atsumi, Munehiro Teranishi, Makoto Shirai, Yoko Suzuki, Shinya Sehata, Isao Igarashi, Takanori Maejima, Sunao Manabe
Publikováno v:
Journal of Toxicologic Pathology. 19:151-154
Connexin32 (Cx32), one of the components of gap junction intercellular communication, is commonly detected by the fluorescent antibody method, although this method has some defects when conducting detailed histopathological investigations. In order t
Autor:
Hiroyuki Nakayama, Takashi Yamoto, Naoki Kiyosawa, Kunio Doi, Koji Uetsuka, Munehiro Teranishi, Kyoko Sakuma, Shinya Sehata, Kazumi Ito
Publikováno v:
Experimental and Toxicologic Pathology. 55:357-366
Summary Pregnant rats on day 13 of gestation were treated orally with T-2 toxin at a single dose of 2 mg/kg and sacrificed at 24 hours after treatment. Histopathologically, apoptosis was increased in the liver, placenta and fetal liver. Microarray an
Autor:
Masaya Takaoka, Shinya Sehata, Takanori Maejima, Toshio Imai, Mikinori Torii, Hiroshi Satoh, Kaoru Toyosawa, Zen-yo Tanakamaru, Tamiko Adachi, Shigeru Hisada, Makoto Ueda, Hiroyuki Ogasawara, Masahiro Matsumoto, Kiyoshi Kobayashi, Mamoru Mutai, Toshimi Usui
Publikováno v:
Toxicologic Pathology. 31:191-199
Publikováno v:
Mycotoxins. 2003:33-39
Autor:
Toshihiko Makino, Mayumi Watanabe, Takanori Maejima, Sunao Manabe, Shinya Sehata, Isao Igarashi, Munehiro Teranishi, Seiya Ogata
Publikováno v:
Journal of Toxicologic Pathology. 16:113-116
Osteosarcomas were found in the lung of a 62-week-old ICR female mouse having malignant systemic lymphoma. Macroscopically, the firm white nodules were located in all lobes of the lungs. Microscopically, the multiple nodules were mainly composed of i
Publikováno v:
Journal of Toxicologic Pathology. 16:59-65
Autor:
Kohji Tanaka, Yoshiro Tani, Shinya Sehata, Takashi Yamoto, Junichiro Fukushige, Tsunemichi Hosokawa, Toshihiko Makino, Naoyuki Maeda, Etsuji Matsumoto, Sunao Manabe, Hideki Yamamoto, Satoko Sato, Mayumi Watanabe, Kazuo Endo, Munehiro Teranishi, Seiya Ogata, Masaya Takaoka
Publikováno v:
Journal of Toxicologic Pathology. 12:119-129
Mini rats, a Wistar-derived transgenic rat strain harboring a rat growth hormone (GH) antisense gene, show lower plasma GH levels than Wistar rats. In our previous study, Mini rats showed a smaller femur size with lower mineral density and a reductio
Autor:
Munehiro Teranishi, Seiya Ogata, Isao Igarashi, Toshihiko Makino, Hideki Yamamoto, Sunao Manabe, Kohji Tanaka, Shinya Sehata, Masaya Takaoka, Naoyuki Maeda, Takashi Yamoto, Kazuo Endo, Tsunemichi Hosokawa, Satoko Sato, Etsuji Matsumoto, Yoshiro Tani, Junichiro Fukushige, Mayumi Watanabe
Publikováno v:
Journal of Toxicologic Pathology. 12:131-140
Growth hormone (GH) plays an important role in longitudinal bone growth, and hypophysectomized rats have generally been used as a model for GH deficiency in humans. Recently, researchers have bred Mini rats, a Wistar-derived transgenic rat strain har