Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Shinya Imada"'
Autor:
Renan Oliveira Corrêa, Pollyana Ribeiro Castro, José Luís Fachi, Vinícius Dias Nirello, Salma El-Sahhar, Shinya Imada, Gabriel Vasconcelos Pereira, Laís Passariello Pral, Nathália Vitoria Pereira Araújo, Mariane Font Fernandes, Valquíria Aparecida Matheus, Jaqueline de Souza Felipe, Arilson Bernardo dos Santos Pereira Gomes, Sarah de Oliveira, Vinícius de Rezende Rodovalho, Samantha Roberta Machado de Oliveira, Helder Carvalho de Assis, Sergio Costa Oliveira, Flaviano Dos Santos Martins, Eric Martens, Marco Colonna, Patrick Varga-Weisz, Marco Aurélio Ramirez Vinolo
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-25 (2023)
Abstract Background The continuous proliferation of intestinal stem cells followed by their tightly regulated differentiation to epithelial cells is essential for the maintenance of the gut epithelial barrier and its functions. How these processes ar
Externí odkaz:
https://doaj.org/article/8662c6ab735449e096273c702971b2ee
Autor:
Renan Oliveira Corrêa, Pollyana Ribeiro Castro, José Luís Fachi, Vinícius Dias Nirello, Salma El‑Sahhar, Shinya Imada, Gabriel Vasconcelos Pereira, Laís Passariello Pral, Nathália Vitoria Pereira Araújo, Mariane Font Fernandes, Valquíria Aparecida Matheus, Jaqueline de Souza Felipe, Arilson Bernardo dos Santos Pereira Gomes, Sarah de Oliveira, Vinícius de Rezende Rodovalho, Samantha Roberta Machado de Oliveira, Helder Carvalho de Assis, Sergio Costa Oliveira, Flaviano Dos Santos Martins, Eric Martens, Marco Colonna, Patrick Varga‑Weisz, Marco Aurélio Ramirez Vinolo
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/81de1b7174d54b62870cee45b83f85ad
Autor:
Tasuku Konno, Takenori Kotani, Jajar Setiawan, Yuka Nishigaito, Naoki Sawada, Shinya Imada, Yasuyuki Saito, Yoji Murata, Takashi Matozaki
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215255 (2019)
Intestinal epithelial cells (IECs) are regenerated continuously from intestinal stem cells (ISCs) near the base of intestinal crypts in order to maintain homeostasis and structural integrity of intestinal epithelium. Epidermal growth factor (EGF) is
Externí odkaz:
https://doaj.org/article/79f9ee7918c6429f9585682d2e650dc1
Autor:
Jung-Ha Park, Takenori Kotani, Tasuku Konno, Jajar Setiawan, Yasuaki Kitamura, Shinya Imada, Yutaro Usui, Naoya Hatano, Masakazu Shinohara, Yasuyuki Saito, Yoji Murata, Takashi Matozaki
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156334 (2016)
The life span of intestinal epithelial cells (IECs) is short (3-5 days), and its regulation is thought to be important for homeostasis of the intestinal epithelium. We have now investigated the role of commensal bacteria in regulation of IEC turnover
Externí odkaz:
https://doaj.org/article/5343b15015534880b56605503cdc2178
Autor:
Shinya Imada, Heaji Shin, Saleh Khawaled, Sven Meckelmann, Charles Whittaker, Renan Correa, Dikshant Pradhan, Gizem Calibasi, Luiza Nascentes Nascentes, Gabriele Allies, Pia Wittenhofer, Oliver Schmitz, Jatin Roper, Marco Vinolo, Chia-Wei Cheng, Alpaslan Tasdogan, Ömer Yilmaz
For more than a century, fasting regimens have improved health, lifespan, and tissue regeneration in diverse organisms, including humans. However, how fasting and post-fast refeeding impact adult stem cells and tumour formation has yet to be explored
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2856c3aeabeaba6fa8193971496dcac
https://doi.org/10.21203/rs.3.rs-2320717/v1
https://doi.org/10.21203/rs.3.rs-2320717/v1
Autor:
Inbal Avraham-Davidi, Simon Mages, Johanna Klughammer, Noa Moriel, Shinya Imada, Matan Hofree, Evan Murray, Jonathan Chen, Karin Pelka, Arnav Mehta, Genevieve M. Boland, Toni Delorey, Leah Caplan, Danielle Dionne, Itay Tirosh, Nir Hacohen, Fei Chen, Omer Yilmaz, Jatin Roper, Orit Rozenblatt-Rosen, Mor Nitzan, Aviv Regev
While advances in single cell genomics have helped to chart the cellular components of tumor ecosystems, it has been more challenging to characterize their specific spatial organization and functional interactions. Here, we combine single cell RNA-se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f29eadadcd40e1cf9e610726b6595443
https://doi.org/10.1101/2022.10.02.508492
https://doi.org/10.1101/2022.10.02.508492
Autor:
Shijie He, Peng Lei, Wenying Kang, Priscilla Cheung, Tao Xu, Miyeko Mana, Chan Young Park, Hongyan Wang, Shinya Imada, Jacquelyn O. Russell, Jianxun Wang, Ruizhi Wang, Ziheng Zhou, Kashish Chetal, Eric Stas, Vidisha Mohad, Peter Bruun-Rasmussen, Ruslan I. Sadreyev, Richard A. Hodin, Yanhang Zhang, David T. Breault, Fernando D. Camargo, Ömer H. Yilmaz, Jeffrey J. Fredberg, Nima Saeidi
Publikováno v:
Gastroenterology. 164:1137-1151.e15
Publikováno v:
Cancer Research. 83:1352-1352
Colorectal cancers (CRCs) are a leading cause of cancer-related death. Most CRCs are immune cold, and do not respond to checkpoint blockade therapy except for microsatellite-high CRCs harboring high mutational burdens. Deciphering the mechanism by wh
SUMMARYIntestinal stem cells (ISCs) depend on niche factors for their proper function. However, the source of these ISC niche factors and how they support ISCs remain controversial due to their redundant expression patterns. Here, we report that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::386cb7d10500f808aac0c277993c8143
https://doi.org/10.1101/2022.01.28.478205
https://doi.org/10.1101/2022.01.28.478205
Publikováno v:
Cell Stem Cell. 29:1246-1261.e6