Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shinya H, Kimura"'
Autor:
Shiho Kitaoka, Ayaka Tomohiro, Shinya Ukeshima, Keyue Liu, Hidenori Wake, Shinya H. Kimura, Yasuhiko Yamamoto, Masahiro Nishibori, Tomoyuki Furuyashiki
Publikováno v:
Cells, Vol 12, Iss 13, p 1789 (2023)
Inflammation has been associated with depression, and innate immune receptors, such as the Toll-like receptor (TLR) 2/4 in the medial prefrontal cortex (mPFC), are crucial for chronic stress-induced depression-related behaviors in mice. HMGB1, a puta
Externí odkaz:
https://doaj.org/article/27c69ea5ac844b8faec9d5a817a4dca8
Autor:
Furuyashiki, Shiho Kitaoka, Ayaka Tomohiro, Shinya Ukeshima, Keyue Liu, Hidenori Wake, Shinya H. Kimura, Yasuhiko Yamamoto, Masahiro Nishibori, Tomoyuki
Publikováno v:
Cells; Volume 12; Issue 13; Pages: 1789
Inflammation has been associated with depression, and innate immune receptors, such as the Toll-like receptor (TLR) 2/4 in the medial prefrontal cortex (mPFC), are crucial for chronic stress-induced depression-related behaviors in mice. HMGB1, a puta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::40c3769bc672495305fc6516a941ae61
Autor:
Takayuki, Nagano, Naohiko, Tsuda, Kenichi, Fujimura, Yuji, Ikezawa, Yuki, Higashi, Shinya H, Kimura
Publikováno v:
Journal of neuroimmunology. 361
Prostaglandin E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebf1241892fc2735881d86b05a9b9b8d
https://pubmed.ncbi.nlm.nih.gov/34610503
https://pubmed.ncbi.nlm.nih.gov/34610503
Autor:
Takayuki Nagano, Yuki Higashi, Yuji Ikezawa, Kenichi Fujimura, Shinya H. Kimura, Naohiko Tsuda
Publikováno v:
Journal of Neuroimmunology. 361:577724
Prostaglandin E2 (PGE2) plays pivotal roles in controlling microglial activation with the EP2 receptor, a PGE2 receptor subtype. Activated microglia are often reported to increase cyclooxygenase (COX)-2 expression, followed by PGE2 production, but it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b45a39e31d666bc8fadfc28dc141d6e8
https://doi.org/10.1016/j.jneuroim.2021.577724
https://doi.org/10.1016/j.jneuroim.2021.577724
Autor:
Daisuke Yamanaka, Ryo Nishiyama, Satoshi Kishimoto, Yukiko Mutaguchi, Takayuki Nagano, Hirohisa Umeki, Anna Ioku, Ayaka Sanada, Shinya H. Kimura, Motohiko Takemura
Publikováno v:
Journal of Neurochemistry. 140:605-612
Prostaglandin E2 (PGE2 ) plays crucial roles in managing microglial activation through the prostanoid EP2 receptor, a PGE2 receptor subtype. In this study, we report that PGE2 enhances interferon-γ (IFN-γ)-induced nitric oxide production in microgl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f028f1b23a1c1acb49c287fbb9330f5
https://doi.org/10.1111/jnc.13926
https://doi.org/10.1111/jnc.13926
Autor:
Shinya H. Kimura, Yuji Ikezawa, Naohiko Tsuda, Motohiko Takemura, Takayuki Nagano, Kenichi Fujimura, Yuki Higashi
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 93:3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5a4e8090b804f61ba23bf4750fe176c
https://doi.org/10.1254/jpssuppl.93.0_3-p-270
https://doi.org/10.1254/jpssuppl.93.0_3-p-270
Publikováno v:
Brain Research. 1568:1-9
Prostaglandin E2 (PGE2) plays a critical role in the modulation of microglial function including migration and phagocytosis through EP2, which increases intracellular cyclic adenosine monophosphate (AMP) concentration. In the present study, we found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d581260846e3e2ed90666c0bf5b37e9
https://doi.org/10.1016/j.brainres.2014.05.011
https://doi.org/10.1016/j.brainres.2014.05.011
Autor:
Takayuki, Nagano, Ryo, Nishiyama, Ayaka, Sanada, Yukiko, Mutaguchi, Anna, Ioku, Hirohisa, Umeki, Satoshi, Kishimoto, Daisuke, Yamanaka, Shinya H, Kimura, Motohiko, Takemura
Publikováno v:
Journal of neurochemistry. 140(4)
Prostaglandin E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e2e6b690dba0ff19a3f51ee46bd5b37
https://pubmed.ncbi.nlm.nih.gov/27973680
https://pubmed.ncbi.nlm.nih.gov/27973680
Autor:
Hiroshi Nojima, Shinya H. Kimura
Publikováno v:
Genes to Cells. 7:869-880
Background: Cyclin G1 is a transcriptional target of p53 and is induced by DNA damage in a p53 dependent manner. Analysis of cyclin G1 disrupted mice demonstrated that cyclin G1 is involved in many of the functions regulated by p53 such as apoptosis,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00a362282262d78e6e0583a3492d8e29
https://doi.org/10.1046/j.1365-2443.2002.00564.x
https://doi.org/10.1046/j.1365-2443.2002.00564.x
Publikováno v:
Oncogene. 20:3290-3300
Cyclin G1 is one of the target genes of the transcription factor p53, and is induced in a p53-dependent manner in response to DNA damage. Although cyclin G1 has been implicated in a range of biological phenomena, its precise function remains unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4cc9fd6c1dee1dc0c1baf0bbf6090f8
https://doi.org/10.1038/sj.onc.1204270
https://doi.org/10.1038/sj.onc.1204270