Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Shinya Aramaki"'
Autor:
Shinya Aramaki, Borami Shin, Saya Kagiwada, Karin Hübner, Hans R. Schöler, Guangming Wu, Jeffrey L. Wrana, Kenjiro Adachi, David Obridge, Eva Kutejova
Publikováno v:
Development (Cambridge, England)
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The germ cell lineage in mammals is induced by the stimulation of pluripotent epiblast cells by signaling molecules. Previous studies have suggested that the germ cell differentiation competence or responsiveness of epiblast cells to signaling molecu
Autor:
David Obridge, Heiko Lickert, Hans R. Schöler, Eva Kutejova, Saya Kagiwada, Karin Hübner, Shinya Aramaki, Kenjiro Adachi, Guangming Wu
Publikováno v:
EMBO Reports
EMBO Rep.:e52553 (2021)
EMBO Rep.:e52553 (2021)
Fine‐tuned dissolution of pluripotency is critical for proper cell differentiation. Here we show that the mesodermal transcription factor, T, globally affects the properties of pluripotency through binding to Oct4 and to the loci of other pluripote
Autor:
Kagiwada, Saya, Shinya Aramaki, Guangming Wu, Borami Shin, Kutejova, Eva, Obridge, David, Adachi, Kenjiro, Wrana, Jeffrey L., Hūbner, Karin, Schöler, Hans R.
Publikováno v:
Development (09501991); 10/15/2021, Vol. 148 Issue 20, p1-12, 12p
Publikováno v:
Cell. 146:519-532
SummaryThe generation of properly functioning gametes in vitro requires reconstitution of the multistepped pathway of germ cell development. We demonstrate here the generation of primordial germ cell-like cells (PGCLCs) in mice with robust capacity f
Publikováno v:
Journal of Reproduction and Development. 56:341-346
The Deleted in Azoospermia-Like (DAZL) protein coded by Dazl gene is a germline-specific RNA-binding protein essential for gametogenesis in vertebrates, and the chicken Dazl gene has also been identified in primordial germ cells (PGCs). However, the
Autor:
Masa-aki Hattori, Shinya Aramaki, Masatoshi Kurokawa, Tomoki Soh, Nobuhiko Yamauchi, Fuminori Sato
Publikováno v:
Molecular and Cellular Biochemistry. 331:193-199
Myogenesis is regulated through the proliferation and differentiation of myoblasts expressing myostatin which functions as a negative regulator by generating Smad signals. Here, we monitored the autocrine action of myostatin in quiescent chicken myob
Publikováno v:
Journal of Reproduction and Development. 55:214-218
The dead end gene, coding an RNA binding protein, is predominantly expressed in the germ cells of vertebrates. Recently, we cloned chicken dead end homologue (CDH) and showed that expression of CDH mRNA is highly specific to primordial germ cells (PG
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 148:550-555
The skeletal muscle of mammals is known to express myostatin (GDF-8) that acts as a potent negative regulator of skeletal muscle growth. However, the function of GDF-8 is not limited to skeletal muscle, because of its ubiquitous expression in fish. H
Autor:
Shinya Aramaki, S. Okuno, Nobuhiko Yamauchi, K. Yamada, Tomoki Soh, Masa-aki Hattori, N. Shibuya
Publikováno v:
Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology. 147:928-933
A primary role of P-glycoprotein (P-gp), encoded by the multidrug resistance type I gene, is to protect against naturally occurring xenotoxics. Recently, the preferential expression of chicken multidrug resistance type I (Cmdr1) was identified in the
Autor:
Ikuhiro Okamoto, Tomonori Nakamura, Kiyotoshi Sekiguchi, Kazuki Kurimoto, Yukihiro Yabuta, Takuya Yamamoto, Shihori Yokobayashi, Mitinori Saitou, Shinya Aramaki, Masato Nakagawa
Publikováno v:
Nucleic Acids Research
Tomonori Nakamura, Yukihiro Yabuta, Ikuhiro Okamoto, Shinya Aramaki, Shihori Yokobayashi. Kazuki Kurimoto, Kiyotoshi Sekiguchi, Masato Nakagawa, Takuya Yamamoto, and Mitinori Saitou, "SC3-seq: a method for highly parallel and quantitative measurement