Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Shinya, Hanashima"'
Autor:
Masamichi Nagae, Yasuhiko Kizuka, Emiko Mihara, Yu Kitago, Shinya Hanashima, Yukishige Ito, Junichi Takagi, Naoyuki Taniguchi, Yoshiki Yamaguchi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
The activity of glycosyltransferase GnT-V correlates with cancer malignancy and poor prognosis but its mechanism of action is poorly understood. Here, the authors solve crystal structures of free and substrate analog-bound GnT-V, providing insights i
Externí odkaz:
https://doaj.org/article/f1b4c8dd92254367b426de0599de41f5
Autor:
Tomokazu Yasuda, Hirofumi Watanabe, Koichiro M. Hirosawa, Kenichi G. N. Suzuki, Keishi Suga, Shinya Hanashima
Publikováno v:
Langmuir. 38:14695-14703
Exosomes are small extracellular vesicles (sEVs) involved in distal cell-cell communication and cancer migration by transferring functional cargo molecules. Membrane domains similar to lipid rafts are assumed to occur in exosome membranes and are inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06d60569a6abf42e158dfec53d9b1903
https://doi.org/10.1021/acs.langmuir.2c02258
https://doi.org/10.1021/acs.langmuir.2c02258
Publikováno v:
Membranes, Vol 11, Iss 11, p 823 (2021)
Membrane proteins reside in the lipid bilayer of biomembranes and the structure and function of these proteins are closely related to their interactions with lipid molecules. Structural analyses of interactions between membrane proteins and lipids or
Externí odkaz:
https://doaj.org/article/040cdbe8bc71420197f593d2859ddc3e
Autor:
Darcy Lacanilao Garza, Shinya Hanashima, Yuichi Umegawa, Michio Murata, Masanao Kinoshita, Nobuaki Matsumori, Peter Greimel
Publikováno v:
Langmuir. 38:10478-10491
The ginsenoside Rh2 (Rh2) is a saponin of medicinal ginseng, and it has attracted much attention for its pharmacological activities. In this study, we investigated the interaction of Rh2 with biological membranes using model membranes. We examined th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ea27455712b58e4eac5380b99ff1f5
https://doi.org/10.1021/acs.langmuir.2c01261
https://doi.org/10.1021/acs.langmuir.2c01261
Publikováno v:
Pure and Applied Chemistry.
Glycosphingolipids (GSLs) in the mammalian plasma membrane are essential for various biological events that occur on cell membranes by forming glycolipid-rich membrane domains, such as lipid rafts. Lactosylceramide (LacCer) forms a highly ordered pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8679998a7125f1b89c9e4d698302de80
https://doi.org/10.1515/pac-2023-0204
https://doi.org/10.1515/pac-2023-0204
Autor:
Shinya Hanashima, Ryuji Ikeda, Yuki Matsubara, Tomokazu Yasuda, Hiroshi Tsuchikawa, J. Peter Slotte, Michio Murata
Publikováno v:
Biophys J
Lactosylceramide (LacCer) in the plasma membranes of immune cells is an important lipid for signaling in innate immunity through the formation of LacCer-rich domains together with cholesterol (Cho). However, the properties of the LacCer domains forme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbcb31f8268dcd946bd0c38c0039f4e9
https://doi.org/10.1016/j.bpj.2022.02.037
https://doi.org/10.1016/j.bpj.2022.02.037
Publikováno v:
Organic & Biomolecular Chemistry. 20:6436-6444
S-Palmitoyl and N-myristoyl chains of Lyn cooperatively facilitate binding to the anionic lipids in membranes by extending the hydrocarbon chains deeper into the membrane interior.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52bb3ae29407552fba7e4248210a8404
https://doi.org/10.1039/d2ob01079h
https://doi.org/10.1039/d2ob01079h
Publikováno v:
Glycolipids ISBN: 9781071629093
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::241c4ad0ff3fa3c839a708f84f0ba0f4
https://doi.org/10.1007/978-1-0716-2910-9_19
https://doi.org/10.1007/978-1-0716-2910-9_19
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2613
Glycosphingolipids (GSLs) in the mammalian plasma membrane are essential for various biological events as they form glycolipid-rich membrane domains, such as lipid rafts. GSLs consist of a certain oligosaccharide head group and a ceramide tail with v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c14c043736aa4fa28a9338dfef2b5bfd
https://pubmed.ncbi.nlm.nih.gov/36587084
https://pubmed.ncbi.nlm.nih.gov/36587084
Effect of the number of sugar units on the interaction between diosgenyl saponin and membrane lipids
Autor:
Joan Candice Ondevilla, Shinya Hanashima, Akane Mukogawa, Darcy Garza Miyazato, Yuichi Umegawa, Michio Murata
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1865:184145
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c41c1edce3ce46e9e328d679d1ebbe
https://doi.org/10.1016/j.bbamem.2023.184145
https://doi.org/10.1016/j.bbamem.2023.184145