Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Shinwoo Kang"'
Autor:
Shinwoo Kang, Jeyeon Lee, Dina N. Ali, Sun Choi, Jarred Nesbitt, Paul H. Min, Eugenia Trushina, Doo-Sup Choi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Alcohol use disorder has been associated with the development of neurodegenerative diseases, including Alzheimer’s disease (AD). However, recent studies demonstrate that moderate alcohol consumption may be protective against dementia and c
Externí odkaz:
https://doaj.org/article/4b6408f843ce404fba7d1d66cd3f7a9b
Publikováno v:
Cells, Vol 13, Iss 4, p 318 (2024)
Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the central nervous system (CNS). Most GABAergic neurons synthesize GABA from glutamate and release it in the synaptic cleft in the CNS. However, astrocytes can also synthesiz
Externí odkaz:
https://doaj.org/article/c100a2be20ea446f81ee161544eb6159
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 16, p 13010 (2023)
Alzheimer’s disease (AD) is one representative dementia characterized by the accumulation of amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain, resulting in cognitive decline and memory loss. AD is associated with neuropsyc
Externí odkaz:
https://doaj.org/article/0b731ae1cdec4150906448314b08ff8c
Autor:
Gowoon Son, Seung-Jun Yoo, Shinwoo Kang, Ameer Rasheed, Da Hae Jung, Hyunjun Park, Bongki Cho, Harry W. M. Steinbusch, Keun-A Chang, Yoo-Hun Suh, Cheil Moon
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-20 (2021)
Abstract Background Hyposmia in Alzheimer’s disease (AD) is a typical early symptom according to numerous previous clinical studies. Although amyloid-β (Aβ), which is one of the toxic factors upregulated early in AD, has been identified in many s
Externí odkaz:
https://doaj.org/article/a75572e81f3d46138b6947724da05a40
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Alzheimer’s disease (AD) is mainly characterized by the deposition of extracellular amyloid plaques and intracellular accumulation of neurofibrillary tangles (NFTs). While the recent 5xFAD AD mouse model exhibits many AD-related phenotypes
Externí odkaz:
https://doaj.org/article/a3e932f78e3d4ee3a5d25253f2715d22
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 15 (2022)
Mitochondria are essential organelles central to various cellular functions such as energy production, metabolic pathways, signaling transduction, lipid biogenesis, and apoptosis. In the central nervous system, neurons depend on mitochondria for ener
Externí odkaz:
https://doaj.org/article/3830ad6cf0ac4fd2bdd3740252839923
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10602 (2022)
Alzheimer’s disease (AD) is a form of dementia associated with abnormal glucose metabolism resulting from amyloid-beta (Aβ) plaques and intracellular neurofibrillary tau protein tangles. In a previous study, we confirmed that carboxy-dehydroevodia
Externí odkaz:
https://doaj.org/article/165efb38ab214f889d55962c8c39c97b
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5485 (2022)
Alzheimer’s disease (AD) is characterized by the deposition of extracellular amyloid plaques and intracellular accumulation of neurofibrillary tangles (NFT). Amyloid beta (Aβ) and tau imaging are widely used for diagnosing and monitoring AD in cli
Externí odkaz:
https://doaj.org/article/f399995cbbad4f8496131111c54955fc
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Polygala tenuifolia Willdenow is a herb known for its therapeutic effects in insomnia, depression, disorientation, and memory impairment. In Alzheimer’s disease (AD) animal model, there has been no report on the effects of memory and cognitive impa
Externí odkaz:
https://doaj.org/article/cf1d53086083490cbea31712c460913f
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Carboxy-dehydroevodiamine·HCl (cx-DHED) is a derivative of DHED, which improves memory impairment. Carboxyl modification increases solubility in water, indicating that its bioavailability is higher than that of DHED. Cx-DHED is expected to have bett
Externí odkaz:
https://doaj.org/article/b2374ab9529b4f6aadf89158b49320c5