Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Shinwon Ha"'
Autor:
Kyung-Won Min, Myung Hyun Jo, Minseok Song, Ji Won Lee, Min Ji Shim, Kyungmin Kim, Hyun Bong Park, Shinwon Ha, Hyejin Mun, Ahsan Polash, Markus Hafner, Jung-Hyun Cho, Dongsan Kim, Ji-Hoon Jeong, Seungbeom Ko, Sungchul Hohng, Sung-Ung Kang, Je-Hyun Yoon
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 1-15 (2024)
ABSTRACTAlthough Argonaute (AGO) proteins have been the focus of microRNA (miRNA) studies, we observed AGO-free mature miRNAs directly interacting with RNA-binding proteins, implying the sophisticated nature of fine-tuning gene regulation by miRNAs.
Externí odkaz:
https://doaj.org/article/2031b122a0b248eea1c5236fa50038ff
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The transcriptional repressor called parkin interacting substrate (PARIS; ZNF746) was initially identified as a novel co-substrate of parkin and PINK1 that leads to Parkinson’s disease (PD) by disrupting mitochondrial biogenesis through pe
Externí odkaz:
https://doaj.org/article/b3049af49e7a40df8697aa04359b1412
Molecular Crosstalk Between Circadian Rhythmicity and the Development of Neurodegenerative Disorders
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Neurodegenerative disorders have been shown to exhibit substantial interconnectedness with circadian rhythmicity. Alzheimer’s patients exhibit high degradation of the suprachiasmatic nucleus (SCN), the central endogenous circadian timekeeper, and P
Externí odkaz:
https://doaj.org/article/68c5846f74cb40e4b2273daa72057428
Autor:
Ank Agarwal, Seongje Park, Shinwon Ha, Ji-Sun Kwon, Mohammed Repon Khan, Bong Gu Kang, Ted M Dawson, Valina L Dawson, Shaida A Andrabi, Sung-Ung Kang
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0231978 (2020)
Ischemic strokes result in the death of brain tissue and a wave of downstream effects, often leading to lifelong disabilities or death. However, the underlying mechanisms of ischemic damage and repair systems remain largely unknown. In order to bette
Externí odkaz:
https://doaj.org/article/9162d4a1f398472f920915525885425b
Autor:
Kyung-Won Min, Myung Hyun Jo, Minsuk Song, Seungbeom Ko, Ji Won Lee, Min Ji Shim, Kyungmin Kim, Hyun Bong Park, Shinwon Ha, Hyejin Mun, Ahsan Polash, Markus Hafner, Jung-Hyun Cho, Dong-San Kim, Sungchul Hohng, Sung-Ung Kang, Je-Hyun Yoon
Although Argonaute (AGO) proteins have been the focus of microRNA (miRNA) studies, we observed AGO-free mature miRNAs directly interacting with RNA-binding proteins, implying the sophisticated nature of fine-tuning gene regulation by miRNAs. To inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b96ffed687bcc4c4b2c87094c355d6c
https://doi.org/10.1101/2023.03.15.532749
https://doi.org/10.1101/2023.03.15.532749
Autor:
Fatih Akkentli, In kyu Jang, Yoonseop Choi, Dongyoon Yoo, Eric Joon-Hun Oh, Chan Hyun Na, Shinwon Ha, Sung-Ung Kang
The aggregation of α-synuclein in the nervous system leads to a class of neurodegenerative disorders termed α-synucleinopathies. A form of primary degenerative dementia called Lewy body dementia (LBD) often develops in the case these aggregations d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faa90a809b1e58aa651723b61701e88a
https://doi.org/10.1101/2022.10.10.511662
https://doi.org/10.1101/2022.10.10.511662
Autor:
Bong Gu Kang, Sung-Ung Kang, Jae Jin Kim, Ji-Sun Kwon, Jean-Philippe Gagné, Seo Yun Lee, Soyeon Kim, Karl L. Sangwon, Shinwon Ha, Jun Seop Jeong, Yun-Il Lee, Heng Zhu, Dongsan Kim, Guy G. Poirier, Ho Chul Kang, Valina L. Dawson, Ted M. Dawson
SUMMARYPoly(ADP-ribose) (PAR) plays a crucial role in intracellular signaling and scaffolding through covalent modification or non-covalent binding to target proteins. The non- covalent binding PARylome has not been extensively characterized. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07a7f16b4c21dbffac2052f89b1abc23
https://doi.org/10.1101/2022.06.06.494829
https://doi.org/10.1101/2022.06.06.494829
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 8289
Autophagy is a cellular catabolic process that degrades and recycles cellular materials. Autophagy is considered to be beneficial to the cell and organism by preventing the accumulation of toxic protein aggregates, removing damaged organelles, and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da091b00a1e04d197a473c57666cb7e0
https://doi.org/10.3390/ijms24098289
https://doi.org/10.3390/ijms24098289
Autor:
Dong Kyu Kim, Hyobin Jeong, Jingi Bae, Moon-Yong Cha, Moonkyung Kang, Dongjin Shin, Shinwon Ha, Seung Jae Hyeon, Hokeun Kim, Kyujin Suh, Mi-Sun Choi, Hoon Ryu, Seong-Woon Yu, Jong-Il Kim, Yeon-Soo Kim, Sang-Won Lee, Daehee Hwang, Inhee Mook-Jung
Publikováno v:
Experimentalmolecular medicine. 54(9)
Mitochondria in neural progenitors play a crucial role in adult hippocampal neurogenesis by being involved in fate decisions for differentiation. However, the molecular mechanisms by which mitochondria are related to the genetic regulation of neurona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dc2c9767cc4b0cc98f4a03fd70e11f
https://pubmed.ncbi.nlm.nih.gov/36056186
https://pubmed.ncbi.nlm.nih.gov/36056186
Autor:
Shinwon Ha, Moonkyung Kang, Inhee Mook-Jung, Hoon Ryu, Mi-Sun Choi, Dong-Kyu Kim, Hokeun Kim, Seong-Woon Yu, Kyujin Suh, Dongjin Shin, Sang Won Lee, Hyobin Jeong, Daehee Hwang, Yeonsoo Kim, Jong Il Kim, Moon-Yong Cha, Jingi Bae, Seung Jae Hyeon
Background Adult hippocampal neurogenesis (AHN) is a process of continuously generating functional mature neurons from neural stem cells in the dentate gyrus. In Alzheimer’s disease (AD) brains, amyloid pathology has deleterious effects on AHN, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86e6f9ff912fc08de0e6766892e004fd
https://doi.org/10.21203/rs.3.rs-114597/v1
https://doi.org/10.21203/rs.3.rs-114597/v1