Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Shintaro Kawai"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/1d6ef515e75d4e74b87677f1c8c9f0d5
Autor:
Senichiro Yanagawa, Hiroyuki Tahara, Takayuki Shirouzu, Shintaro Kawai, Yuka Tanaka, Kentaro Ide, Shuji Akimoto, Hideki Ohdan
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0236614 (2021)
In organ transplantation, human leukocyte antigen (HLA)-mismatch grafts not only induce the activation of cellular mediated immune response but also the development of chronic antibody-mediated rejection due to the donor-specific anti-HLA antibody (D
Externí odkaz:
https://doaj.org/article/1e9cce66a4db422e8f54e382392cbbd2
Autor:
Shinobu Tamura, Takahiro Kaki, Mayako Niwa, Yukiko Yamano, Shintaro Kawai, Yusuke Yamashita, Harumi Tanaka, Yoshinobu Saito, Yoshinori Kajimoto, Yusuke Koizumi, Hiroki Yamaue, Naoyuki Nakao, Takako Nojiri, Masaya Hironishi
Publikováno v:
Medicina, Vol 58, Iss 1, p 118 (2022)
Background and Objectives: The incidence of coronavirus disease 2019 (COVID-19) has increased in Wakayama, Japan, due to the spread of the highly infectious B.1.1.7 variant. Before this event, the medical systems were almost unaffected. We aimed to a
Externí odkaz:
https://doaj.org/article/9ac4bbd5c0fc4bbabee88e4907439403
Autor:
Ken Takeshima, Hiroyuki Ariyasu, Tatsuya Ishibashi, Shintaro Kawai, Shinsuke Uraki, Jinsoo Koh, Hidefumi Ito, Takashi Akamizu
Publikováno v:
Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-6 (2018)
Myotonic dystrophy type 1 (DM1) is an autosomal dominant multisystem disease affecting muscles, the eyes and the endocrine organs. Diabetes mellitus and primary hypogonadism are endocrine manifestations typically seen in patients with DM1. Abnormalit
Externí odkaz:
https://doaj.org/article/694453ff4ccb41d6b5405291d07d2636
Autor:
Takuro Uchida, Yuji Teraoka, Michio Imamura, Hiromi Abe‐Chayama, Grace Naswa Makokha, Clair Nelson Hayes, Hiroshi Aikata, Satoko Hamamura, Yuji Ishida, Chise Tateno, Takayuki Shirouzu, Shintaro Kawai, Yuka Tanaka, Hideki Ohdan, Seiji Okada, Kazuaki Chayama
Publikováno v:
Journal of Viral Hepatitis. 30:262-272
Autor:
Takuro, Uchida, Teraoka, Yuji, Michio, Imamura, Hiromi, Abe-Chayama, Grace Naswa, Makokha, C Nelson, Hayes, Hiroshi, Aikata, Satoko, Hamamura, Yuji, Ishida, Chise, Tateno, Takayuki, Shirouzu, Shintaro, Kawai, Yuka, Tanaka, Hideki, Ohdan, Seiji, Okada, Kazuaki, Chayama
Publikováno v:
Journal of viral hepatitis.
Although human hepatocyte-transplanted immunodeficient mice support infection with hepatitis viruses, these mice fail to develop viral hepatitis due to the lack of an adaptive immune system. In this study, we generated new immunodeficiency cDNA-uroki
Publikováno v:
Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.
Publikováno v:
Cell Biochemistry and Function. 38:392-400
The circumventricular organs (CVOs) are the brain regions that lack the blood-brain barrier and allow free entry of blood-derived molecules, offering specialized niche to initiate rapid and early neuroinflammatory responses in the brain. Complement c
Autor:
Hiromi Abe-Chayama, Daiki Miki, C. Nelson Hayes, Yuka Tanaka, Seiji Okada, Chise Tateno, Takayuki Shirouzu, Yuji Ishida, Takashi Nakahara, Kazuaki Chayama, Grace Naswa Makokha, Shintaro Kawai, Tomokazu Kawaoka, Hatsue Fujino, Hideki Ohdan, Eisuke Murakami, Atsushi Ono, Masami Yamauchi, Satoko Hamamura, Michio Imamura, Takuro Uchida, Yuji Teraoka, Hiroshi Aikata
The humanized mouse is a widely used in vivo model for the investigation of pathogenesis and drug development. In this study, we generated new immunodeficiency cDNA-urokinase-type plasminogen activator (uPA)/SCID/Rag2-/-/Jak3-/- mice and established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2858743026c98688a78dc645a138d68f
https://doi.org/10.21203/rs.3.rs-712014/v1
https://doi.org/10.21203/rs.3.rs-712014/v1
Autor:
Tsukasa Nakamura, Takayuki Shirouzu, Ryusuke Sugimoto, Shumpei Harada, Mikiko Yoshikawa, Shuji Nobori, Hidetaka Ushigome, Shintaro Kawai
Publikováno v:
Transplantation proceedings. 54(2)
There is no doubt that antibody-mediated rejection (AMR) due to donor-specific anti-HLA antibodies (DSA) brings a poor outcome for liver transplant recipients. However, the relationship between intragraft DSA (g-DSA), complement-binding abilities, an