Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Shintaro, Akiyama"'
Autor:
Shintaro Akiyama, Suguru Nishijima, Yasushi Kojima, Moto Kimura, Mitsuru Ohsugi, Kohjiro Ueki, Masashi Mizokami, Masahira Hattori, Kiichiro Tsuchiya, Naomi Uemura, Takashi Kawai, Peer Bork, Naoyoshi Nagata
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract The integrative multi-kingdom interaction of the gut microbiome in ulcerative colitis (UC) and Crohn’s disease (CD) remains underinvestigated. Here, we perform shotgun metagenomic sequencing of feces from patients with UC and CD, and healt
Externí odkaz:
https://doaj.org/article/b782f6491b704ca2898a64c94ecf9d47
Publikováno v:
Intestinal Research, Vol 22, Iss 4, Pp 389-396 (2024)
A therapeutic goal for patients with ulcerative colitis (UC) is deep remission including clinical remission and mucosal healing. Mucosal healing was previously defined by endoscopic appearance, but recent studies demonstrate that histological improve
Externí odkaz:
https://doaj.org/article/17f895b95a5547b38882c68277601ba0
Autor:
Shintaro Akiyama, Tsubasa Onoda, Shoko Moue, Noriaki Sakamoto, Taku Sakamoto, Hideo Suzuki, Tsuyoshi Enomoto, Daisuke Matsubara, Tatsuya Oda, Kiichiro Tsuchiya
Publikováno v:
Intestinal Research, Vol 22, Iss 1, Pp 92-103 (2024)
Background/Aims Mucosal adaptation of the ileum toward colonic epithelium has been reported in pouchitis in ulcerative colitis (UC); however, the clinical characteristics, endoscopic findings, and outcomes in patients with pouchitis with ileal mucosa
Externí odkaz:
https://doaj.org/article/6addfae59f0245699f0d71630a07af75
Autor:
Mariko Kobayashi, Shintaro Akiyama, Toshiaki Narasaka, Katsumasa Kobayashi, Atsushi Yamauchi, Atsuo Yamada, Jun Omori, Takashi Ikeya, Taiki Aoyama, Naoyuki Tominaga, Yoshinori Sato, Takaaki Kishino, Naoki Ishii, Tsunaki Sawada, Masaki Murata, Akinari Takao, Kazuhiro Mizukami, Ken Kinjo, Shunji Fujimori, Takahiro Uotani, Minoru Fujita, Hiroki Sato, Sho Suzuki, Junnosuke Hayasaka, Tomohiro Funabiki, Yuzuru Kinjo, Akira Mizuki, Shu Kiyotoki, Tatsuya Mikami, Ryosuke Gushima, Hiroyuki Fujii, Yuta Fuyuno, Naohiko Gunji, Yosuke Toya, Kazuyuki Narimatsu, Noriaki Manabe, Koji Nagaike, Tetsu Kinjo, Yorinobu Sumida, Sadahiro Funakoshi, Kiyonori Kobayashi, Tamotsu Matsuhashi, Yuga Komaki, Kiichiro Tsuchiya, Mitsuru Kaise, Naoyoshi Nagata
Publikováno v:
JGH Open, Vol 7, Iss 7, Pp 487-496 (2023)
Abstract Background and Aim While short and long attachment caps are available for colonoscopy, it is unclear which type is more appropriate for stigmata of recent hemorrhage (SRH) identification in acute hematochezia. This study aimed to compare the
Externí odkaz:
https://doaj.org/article/01f324aafe224b5790180e0b442ac48f
Autor:
Daichi Shigemizu, Shintaro Akiyama, Mutsumi Suganuma, Motoki Furutani, Akiko Yamakawa, Yukiko Nakano, Kouichi Ozaki, Shumpei Niida
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Late-onset Alzheimer’s disease (LOAD) is the most common multifactorial neurodegenerative disease among elderly people. LOAD is heterogeneous, and the symptoms vary among patients. Genome-wide association studies (GWAS) have identified gen
Externí odkaz:
https://doaj.org/article/9b2d5037243f473882505ff3825d9fb4
Autor:
Taku Sakamoto, Shintaro Akiyama, Toshiaki Narasaka, Hideo Suzuki, Shigeki Sekine, Yutaka Saito, Kiichiro Tsuchiya
Publikováno v:
Journal of the Anus, Rectum and Colon, Vol 6, Iss 2, Pp 92-99 (2022)
Anal squamous cell carcinoma (SCC) is rare, but it has been commonly detected as an invasive cancer. The standard treatment for anal SCC was surgical resection. However, recent medical advances have enabled the standard treatment to be chemoradiother
Externí odkaz:
https://doaj.org/article/bc3c4b50b3d14c06b207087983f6e9f5
Autor:
Yuya Asanomi, Daichi Shigemizu, Shintaro Akiyama, Takashi Sakurai, Kouichi Ozaki, Takahiro Ochiya, Shumpei Niida
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract There are many subtypes of dementia, and identification of diagnostic biomarkers that are minimally-invasive, low-cost, and efficient is desired. Circulating microRNAs (miRNAs) have recently gained attention as easily accessible and non-inva
Externí odkaz:
https://doaj.org/article/f17afa2b403d4008b85b2c5299309e06
Autor:
Akihiro Fujimoto, Jing Hao Wong, Yukiko Yoshii, Shintaro Akiyama, Azusa Tanaka, Hitomi Yagi, Daichi Shigemizu, Hidewaki Nakagawa, Masashi Mizokami, Mihoko Shimada
Publikováno v:
Genome Medicine, Vol 13, Iss 1, Pp 1-15 (2021)
Abstract Background Identification of germline variation and somatic mutations is a major issue in human genetics. However, due to the limitations of DNA sequencing technologies and computational algorithms, our understanding of genetic variation and
Externí odkaz:
https://doaj.org/article/bc8e6c29eecc44cf9b422cc28d4fda86
Autor:
Daichi Shigemizu, Risa Mitsumori, Shintaro Akiyama, Akinori Miyashita, Takashi Morizono, Sayuri Higaki, Yuya Asanomi, Norikazu Hara, Gen Tamiya, Kengo Kinoshita, Takeshi Ikeuchi, Shumpei Niida, Kouichi Ozaki
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Alzheimer’s disease (AD) has no cure, but early detection and risk prediction could allow earlier intervention. Genetic risk factors may differ between ethnic populations. To discover novel susceptibility loci of AD in the Japanese populat
Externí odkaz:
https://doaj.org/article/6883b0ed97624f228352830deaf10700
Publikováno v:
Intestinal Research, Vol 19, Iss 1, Pp 1-11 (2021)
Patients with inflammatory bowel disease (IBD) occasionally need a restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) because of medically refractory colitis or dysplasia/cancer. However, pouchitis may develop in up to 70% of patien
Externí odkaz:
https://doaj.org/article/e596223ea35a420bb4b02971bd19a30d