Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shinta Kobayashi"'
Autor:
Evan Vosburgh, Yi-Chieh Nancy Du, Tanupriya Contractor, Shinta Kobayashi, Laura H. Tang, Chris R. Harris, Richard Clausen
Publikováno v:
Oncogenesis, Vol 8, Iss 3, Pp 1-13 (2019)
Oncogenesis
Oncogenesis
The two most common types of pancreatic neuroendocrine tumors (PanNETs) are insulinomas and nonfunctioning PanNETs (NF-PanNETs). Insulinomas are small, rarely metastatic tumors that secrete high amounts of insulin, and nonfunctioning PanNETs are larg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15862f9be37d32e537d430bd00698309
https://doi.org/10.1038/s41389-019-0127-1
https://doi.org/10.1038/s41389-019-0127-1
Autor:
Shinta Kobayashi, Laura H. Tang, Evan Vosburgh, Richard Clausen, Arnold J. Levine, Chang S. Chan, Tanupriya Contractor, Chris R. Harris, Edaise M da Silva
Publikováno v:
Oncotarget
In a mouse model for neuroendocrine tumors of the pancreas (PanNETs), liver metastasis occurred at a higher frequency in males. Male mice also had higher serum and intratumoral levels of the innate immunity protein complement C5. In mice that lost th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aba636e4b862826214c48ac7720326ca
https://doi.org/10.18632/oncotarget.8874
https://doi.org/10.18632/oncotarget.8874
Publikováno v:
Experimental Cell Research. 313:1675-1686
Dynamin-like protein 1 (DLP1) and Pex11p{beta} function in morphogenesis of peroxisomes. In the present work, we investigated whether Fis1 is involved in fission of peroxisomes. Endogenous Fis1 was morphologically detected in peroxisomes as well as m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7e8471a670023b447f05899123eb30
https://doi.org/10.1016/j.yexcr.2007.02.028
https://doi.org/10.1016/j.yexcr.2007.02.028
Publikováno v:
Experimental Cell Research. 312:1671-1684
We earlier isolated a Chinese hamster ovary cell line ZP121 showing morphologically abnormal, tubular peroxisomes, and apparent dysmorphogenesis of mitochondria. Here, we identified an inactivating point-mutation in dynamin-like protein 1 gene, DLP1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fcaea0386cb29fbb907bf5a5f5afd78
https://doi.org/10.1016/j.yexcr.2006.01.028
https://doi.org/10.1016/j.yexcr.2006.01.028
Publikováno v:
Cancer Research. 77:2260-2260
Neuroendocrine tumors are the most common tumors of the small intestine. Very little is known about genetic changes that cause SI-NETs, which have a very low frequency of mutations. SI-NETs are highly metastatic to the liver, and patients with liver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bedadeb1b4b19f687e2ecbdb261deb02
https://doi.org/10.1158/1538-7445.am2017-2260
https://doi.org/10.1158/1538-7445.am2017-2260
Autor:
Tanupriya Contractor, Shinta Kobayashi, Edaise M da Silva, Laura H. Tang, Chang S. Chan, Richard Clausen, Chris R. Harris
Publikováno v:
Cancer Research. 76:478-478
Pancreatic neuroendocrine tumors are generally classified as functioning or nonfunctioning. Patients with functioning tumors can have severe hypoglycemia because their tumors express high amounts of insulin as well as chromogranin A; fortunately, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8c0525d9e05a7a6d1ea2c2d238635c3
https://doi.org/10.1158/1538-7445.am2016-478
https://doi.org/10.1158/1538-7445.am2016-478
Autor:
Masami Suzuki, Hironori Mutoh, Kenji Yoshida, Yu Jau Chen, Takashi Yoshikubo, Shinichi Funahashi, Shinta Kobayashi, Arnold J. Levine, Atsuhiko Kato, Hisafumi Yamada-Okabe, Takahiro Ochiya, Osamu Natori, Norikazu Tamaoki, Takeshi Watanabe, Yamazaki Tatsumi, Chie Kato, Masahiko Kuroda, Eri Hashimoto, Masaki Yamazaki, Motooki Ashihara, Koichi Matsubara, Yoshinori Watanabe
Publikováno v:
Stem cells (Dayton, Ohio). 30(12)
The cancer stem cell (CSC) concept has been proposed as an attractive theory to explain cancer development, and CSCs themselves have been considered as targets for the development of diagnostics and therapeutics. However, many unanswered questions co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ea5eb02867036f9389cbbc3d1f387bf
https://pubmed.ncbi.nlm.nih.gov/23081779
https://pubmed.ncbi.nlm.nih.gov/23081779
Autor:
Arnold J. Levine, Edaise M da Silva, Evan Vosburgh, Laura H. Tang, Chang S. Chan, Yvonne Sun, Shinta Kobayashi, Chris R. Harris, Tanupriya Contractor, Richard Clausen
Publikováno v:
Cancer Research. 75:3185-3185
Among patients with neuroendocrine tumors, males are more likely than females to develop liver metastatic disease. We show that this male bias toward liver metastasis is also observed in a mouse model for pancreatic neuroendocrine tumorigenesis (PanN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07342ac74cb1f54774719297e840672d
https://doi.org/10.1158/1538-7445.am2015-3185
https://doi.org/10.1158/1538-7445.am2015-3185